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Aliases for MIR30C1 Gene

Subcategory (RNA class) for MIR30C1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR30C1 Gene

  • MicroRNA 30c-1 2 3
  • Hsa-Mir-30c-1 3
  • MIRN30C1 3

External Ids for MIR30C1 Gene

ORGUL Members for MIR30C1 Gene

Previous Symbols for MIR30C1 Gene

  • MIRN30C1

Summaries for MIR30C1 Gene

Entrez Gene Summary for MIR30C1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR30C1 Gene

MIR30C1 (MicroRNA 30c-1) is an RNA Gene, and belongs to the miRNA class. Diseases associated with MIR30C1 include familial breast cancer and esophageal cancer. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR30C1 Gene

Genomics for MIR30C1 Gene

Genomic Location for MIR30C1 Gene

Start:
40,757,284 bp from pter
End:
40,757,372 bp from pter
Size:
89 bases
Orientation:
Plus strand

Genomic View for MIR30C1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR30C1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR30C1 Gene

No data available for Regulatory Elements for MIR30C1 Gene

Proteins for MIR30C1 Gene

Post-translational modifications for MIR30C1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR30C1 Gene

Domains for MIR30C1 Gene

Gene Families for MIR30C1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR30C1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR30C1 Gene

Function for MIR30C1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR30C1 Gene

Localization for MIR30C1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR30C1 Gene

Pathways for MIR30C1 Gene

SuperPathways for MIR30C1 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR30C1: view

Pathways by source for MIR30C1 Gene

1 KEGG pathway for MIR30C1 Gene

Interacting Proteins for MIR30C1 Gene

Gene Ontology (GO) - Biological Process for MIR30C1 Gene

None

Transcripts for MIR30C1 Gene

mRNA/cDNA for MIR30C1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR30C1 Gene

No ASD Table

Relevant External Links for MIR30C1 Gene

GeneLoc Exon Structure for
MIR30C1
ECgene alternative splicing isoforms for
MIR30C1

Expression for MIR30C1 Gene

mRNA expression in normal human tissues for MIR30C1 Gene

genes like me logo Genes that share expressions with MIR30C1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR30C1 Gene

Orthologs for MIR30C1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR30C1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-30c-1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-30c 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-30c-1 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir30c-1 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-30c-2 36
  • 99 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-30c-1 36
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-30c-1 36
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 85 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-30c 36
  • 70 (a)
OneToMany
Species with no ortholog for MIR30C1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR30C1 Gene

ENSEMBL:
Gene Tree for MIR30C1 (if available)
TreeFam:
Gene Tree for MIR30C1 (if available)

Paralogs for MIR30C1 Gene

No data available for Paralogs for MIR30C1 Gene

Variants for MIR30C1 Gene

Relevant External Links for MIR30C1 Gene

HapMap Linkage Disequilibrium report
MIR30C1
Human Gene Mutation Database (HGMD)
MIR30C1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR30C1 Gene

Disorders for MIR30C1 Gene

Relevant External Links for MIR30C1

Genetic Association Database (GAD)
MIR30C1
Human Genome Epidemiology (HuGE) Navigator
MIR30C1
genes like me logo Genes that share disorders with MIR30C1: view

No data available for UniProtKB/Swiss-Prot for MIR30C1 Gene

Publications for MIR30C1 Gene

  1. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 48
  2. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PMID: 19138993) Ye Y. … Wu X. (Cancer Prev Res (Phila) 2008) 3 48
  3. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J. … Wu X. (Mol. Carcinog. 2010) 3 48
  4. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. (PMID: 20732906) Lin J. … Wu X. (Carcinogenesis 2010) 3 48
  5. Genetic polymorphisms in the precursor MicroRNA flanking region and non-small cell lung cancer survival. (PMID: 20889907) Hu Z. … Shen H. (Am. J. Respir. Crit. Care Med. 2011) 3

Products for MIR30C1 Gene

Sources for MIR30C1 Gene

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