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Aliases for MIR30C1 Gene

Subcategory (RNA class) for MIR30C1 Gene


Quality Score for this RNA gene is


Aliases for MIR30C1 Gene

  • MicroRNA 30c-1 2 3 5
  • Hsa-Mir-30c-1 3
  • Mir-30c-1 3
  • MIRN30C1 3
  • MiR-30c 3

External Ids for MIR30C1 Gene

ORGUL Members for MIR30C1 Gene

Previous HGNC Symbols for MIR30C1 Gene

  • MIRN30C1

Previous GeneCards Identifiers for MIR30C1 Gene

  • GC01P040996
  • GC01P041222

Summaries for MIR30C1 Gene

Entrez Gene Summary for MIR30C1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR30C1 Gene

MIR30C1 (MicroRNA 30c-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR30C1 Gene

Genomics for MIR30C1 Gene

Regulatory Elements for MIR30C1 Gene

Enhancers for MIR30C1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F040708 1.4 FANTOM5 ENCODE 11.2 -46.0 -46046 6.1 PKNOX1 ARNT WRNIP1 ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 ZNF143 RIMS3 LOC105378674 EXO5 MIR30E MIR30C1 RLF LOC101929901 ZFP69 NFYC KCNQ4
GH01F040698 1.4 FANTOM5 Ensembl ENCODE 11.2 -55.4 -55384 7.4 HDGF TBP HDAC1 CBX3 ATF1 ZNF121 CBX5 FOS CREM ZNF362 RIMS3 LOC105378674 MIR30E MIR30C1 NFYC ZNF684 ZFP69 LOC105378672 KCNQ4 EXO5
GH01F040690 1.2 ENCODE 11.1 -64.6 -64583 4.4 CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF263 SP3 NFYC TBX21 MEF2D RIMS3 EXO5 LOC105378674 LOC105378672 ENSG00000235358 MIR30C1 MIR30E ZFP69 KCNQ4 NFYC-AS1
GH01F040801 1.2 Ensembl ENCODE 11.1 +45.4 45417 3.0 HDGF ATF1 ARNT GLIS2 ZNF207 DEK ZNF263 SP3 NCOA1 REST MIR30C1 MIR30E NFYC KCNQ4 NFYC-AS1 GC01M040775
GH01F040943 1.2 Ensembl ENCODE 11 +188.1 188097 2.9 ELF3 RAD21 RARA RFX5 YY1 ZNF366 RCOR1 FOS DEK MIXL1 CITED4 ENSG00000229528 CTPS1 MIR30E MIR30C1 NFYC EXO5 ENSG00000235358 GC01P040947 UBE2V1P8
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR30C1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR30C1 Gene

40,757,284 bp from pter
40,757,372 bp from pter
89 bases
Plus strand

Genomic View for MIR30C1 Gene

Genes around MIR30C1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR30C1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR30C1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR30C1 Gene

Proteins for MIR30C1 Gene

Post-translational modifications for MIR30C1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR30C1 Gene

Domains & Families for MIR30C1 Gene

Gene Families for MIR30C1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR30C1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR30C1 Gene

Function for MIR30C1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR30C1 Gene

Localization for MIR30C1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR30C1 Gene

Pathways & Interactions for MIR30C1 Gene

SuperPathways for MIR30C1 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR30C1: view

Pathways by source for MIR30C1 Gene

1 KEGG pathway for MIR30C1 Gene

Interacting Proteins for MIR30C1 Gene

Gene Ontology (GO) - Biological Process for MIR30C1 Gene


No data available for SIGNOR curated interactions for MIR30C1 Gene

Transcripts for MIR30C1 Gene

mRNA/cDNA for MIR30C1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR30C1 Gene

No ASD Table

Relevant External Links for MIR30C1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR30C1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR30C1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR30C1 Gene:

genes like me logo Genes that share expression patterns with MIR30C1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR30C1 Gene

Orthologs for MIR30C1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR30C1 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia cfa-mir-30c-1 35
  • 100 (a)
(Pan troglodytes)
Mammalia ptr-mir-30c-1 35
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-mir-30c-2 35
  • 99 (a)
(Mus musculus)
Mammalia Mir30c-1 35
  • 99 (a)
(Bos Taurus)
Mammalia bta-mir-30c 35
  • 83 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-30c-1 35
  • 82 (a)
(Gallus gallus)
Aves gga-mir-30c-1 35
  • 92 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 85 (a)
(Danio rerio)
Actinopterygii dre-mir-30c 35
  • 70 (a)
Species where no ortholog for MIR30C1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR30C1 Gene

Gene Tree for MIR30C1 (if available)
Gene Tree for MIR30C1 (if available)

Paralogs for MIR30C1 Gene

No data available for Paralogs for MIR30C1 Gene

Variants for MIR30C1 Gene

Sequence variations from dbSNP and Humsavar for MIR30C1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs113261605 -- 40,757,413(+) CAGAT(C/G/T)GGACA intron-variant, downstream-variant-500B
rs113620251 -- 40,756,704(+) GTTGG(C/G)TTTAA intron-variant, upstream-variant-2KB
rs114367126 -- 40,756,191(+) GGCTT(C/T)TGTTT intron-variant, upstream-variant-2KB
rs116112475 -- 40,756,486(+) TGGCT(A/G)TCAAG intron-variant, upstream-variant-2KB
rs116590100 -- 40,756,708(+) GGTTT(A/G)AGAGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR30C1 Gene

Variant ID Type Subtype PubMed ID
esv3577821 CNV loss 25503493

Relevant External Links for MIR30C1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR30C1 Gene

Disorders for MIR30C1 Gene

Relevant External Links for MIR30C1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR30C1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR30C1 Gene

Publications for MIR30C1 Gene

  1. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J. … Wu X. (Mol. Carcinog. 2010) 3 46 64
  2. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. (PMID: 20732906) Lin J. … Wu X. (Carcinogenesis 2010) 3 46 64
  3. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 46 64
  4. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PMID: 19138993) Ye Y. … Wu X. (Cancer Prev Res (Phila) 2008) 3 46 64
  5. Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR-30c in breast cancer. (PMID: 26707189) Yen M.C. … Kuo P.L. (Oncol. Rep. 2016) 3 64

Products for MIR30C1 Gene

Sources for MIR30C1 Gene

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