Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3074 Gene

Subcategory (RNA class) for MIR3074 Gene

miRNA

Quality Score for this RNA gene is

8.2

Aliases for MIR3074 Gene

  • MicroRNA 3074 2 3 5
  • Hsa-Mir-3074 3
  • Mir-3074 3

External Ids for MIR3074 Gene

Previous GeneCards Identifiers for MIR3074 Gene

  • GC09U901548
  • GC09M067457
  • GC09M097848

Summaries for MIR3074 Gene

Entrez Gene Summary for MIR3074 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3074 Gene

MIR3074 (MicroRNA 3074) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are DNA Damage Response and miRNAs involved in DNA damage response.

fRNAdb sequence ontologies for MIR3074 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR3074

Additional gene information for MIR3074 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR3074 Gene

Genomics for MIR3074 Gene

Regulatory Elements for MIR3074 Gene

Enhancers for MIR3074 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H095016 1.5 Ensembl ENCODE dbSUPER 12.2 +64.2 64247 10 PKNOX1 ATF1 FOXA2 ARID4B SIN3A DMAP1 YY1 FOS ATF7 NFYC MIR23B MIR27B MIR3074 C9orf3 MIR6081 LOC101928119
GH09H095053 1.3 Ensembl ENCODE dbSUPER 12.6 +29.2 29223 6 TAL1 JUN MAX FEZF1 RAD21 ZIC2 HIC1 ZFHX2 POLR2A PRDM10 MIR23B MIR27B MIR3074 MIR6081 LOC101928119
GH09H095060 1.1 ENCODE dbSUPER 13.7 +22.1 22127 5 FOXA2 ATF1 ARID4B RAD21 RARA YY1 CREM THAP11 SP5 USF2 MIR23B MIR27B MIR3074 C9orf3 MIR6081 LOC101928119
GH09H095106 0.7 ENCODE dbSUPER 12.7 -21.5 -21527 2 ZNF316 MAFK MIR23B MIR27B MIR3074 PIR48893 PIR51992
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3074 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3074 Gene

Chromosome:
9
Start:
95,086,014 bp from pter
End:
95,086,094 bp from pter
Size:
81 bases
Orientation:
Minus strand

Genomic View for MIR3074 Gene

Genes around MIR3074 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3074 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3074 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3074 Gene

ORGUL Member Location for MIR3074 Gene

ORGUL Member Location for MIR3074 gene

Proteins for MIR3074 Gene

Post-translational modifications for MIR3074 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3074 Gene

Domains & Families for MIR3074 Gene

Gene Families for MIR3074 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3074: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3074 Gene

Function for MIR3074 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3074
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3074 Gene

Localization for MIR3074 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3074 Gene

Pathways & Interactions for MIR3074 Gene

No data available for SIGNOR curated interactions for MIR3074 Gene

Drugs & Compounds for MIR3074 Gene

No Compound Related Data Available

Transcripts for MIR3074 Gene

fRNAdb Secondary structures for MIR3074 Gene

  • hsa-miR-3074-5p_MIMAT0019208_Homo_sapiens_miR-3074-5p_mature

mRNA/cDNA for MIR3074 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3074
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3074 Gene

No ASD Table

Relevant External Links for MIR3074 Gene

GeneLoc Exon Structure for
MIR3074
ECgene alternative splicing isoforms for
MIR3074

Expression for MIR3074 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3074 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3074 Gene:

MIR3074
genes like me logo Genes that share expression patterns with MIR3074: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3074 Gene

Orthologs for MIR3074 Gene

Evolution for MIR3074 Gene

ENSEMBL:
Gene Tree for MIR3074 (if available)
TreeFam:
Gene Tree for MIR3074 (if available)

No data available for Orthologs for MIR3074 Gene

Paralogs for MIR3074 Gene

No data available for Paralogs for MIR3074 Gene

Variants for MIR3074 Gene

Sequence variations from dbSNP and Humsavar for MIR3074 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000887918 -- 95,086,259(+) TAGAC(C/T)TGGAA intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs1001174130 -- 95,087,437(+) GAGAT(C/T)GCGCC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1001236818 -- 95,086,454(+) GTGTA(C/T)GCAAA intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs1001623597 -- 95,087,250(+) GAGGC(C/T)GAGGT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1006024541 -- 95,085,625(+) GGTGC(A/G)GAGCG intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR3074 Gene

Variant ID Type Subtype PubMed ID
nsv1038106 CNV gain 25217958
nsv1147999 OTHER inversion 26484159
nsv831656 CNV loss 17160897

Relevant External Links for MIR3074 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3074

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3074 Gene

Disorders for MIR3074 Gene

Relevant External Links for MIR3074

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3074

No disorders were found for MIR3074 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3074 Gene

Publications for MIR3074 Gene

  1. High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus. (PMID: 27835701) Navarro-Quiroz E … Aroca G (PloS one 2016) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 60
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR3074 Gene

Sources for MIR3074 Gene

Content
Loading form....