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Aliases for MIR3074 Gene

Subcategory (RNA class) for MIR3074 Gene

miRNA

Quality Score for this RNA gene is

8.2

Aliases for MIR3074 Gene

  • MicroRNA 3074 2 3
  • Hsa-Mir-3074 3

External Ids for MIR3074 Gene

Previous GeneCards Identifiers for MIR3074 Gene

  • GC09U901548
  • GC09M067457
  • GC09M097848

Summaries for MIR3074 Gene

Entrez Gene Summary for MIR3074 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3074 Gene

MIR3074 (MicroRNA 3074) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are miRNAs involved in DDR.

fRNAdb sequence ontologies for MIR3074 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR3074

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR3074 Gene

Genomics for MIR3074 Gene

Genomic Location for MIR3074 Gene

Start:
95,086,012 bp from pter
End:
95,086,096 bp from pter
Size:
85 bases
Orientation:
Minus strand

Genomic View for MIR3074 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR3074 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3074 Gene

ORGUL Member Location for MIR3074 Gene

ORGUL Member Location for MIR3074 gene

No data available for Regulatory Elements for MIR3074 Gene

Proteins for MIR3074 Gene

Post-translational modifications for MIR3074 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3074 Gene

Domains for MIR3074 Gene

Gene Families for MIR3074 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3074: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3074 Gene

Function for MIR3074 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR3074 Gene

Localization for MIR3074 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3074 Gene

Pathways for MIR3074 Gene

SuperPathways for MIR3074 Gene

Superpath Contained pathways
1 miRNAs involved in DDR
genes like me logo Genes that share pathways with MIR3074: view

Pathways by source for MIR3074 Gene

1 BioSystems pathway for MIR3074 Gene

Interacting Proteins for MIR3074 Gene

Gene Ontology (GO) - Biological Process for MIR3074 Gene

None

Transcripts for MIR3074 Gene

fRNAdb Secondary structures for MIR3074 Gene

  • hsa-miR-3074-5p_MIMAT0019208_Homo_sapiens_miR-3074-5p_mature

mRNA/cDNA for MIR3074 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3074 Gene

No ASD Table

Relevant External Links for MIR3074 Gene

GeneLoc Exon Structure for
MIR3074
ECgene alternative splicing isoforms for
MIR3074

Expression for MIR3074 Gene

mRNA expression in normal human tissues for MIR3074 Gene

genes like me logo Genes that share expressions with MIR3074: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR3074 Gene

Orthologs for MIR3074 Gene

Evolution for MIR3074 Gene

ENSEMBL:
Gene Tree for MIR3074 (if available)
TreeFam:
Gene Tree for MIR3074 (if available)

No data available for Orthologs for MIR3074 Gene

Paralogs for MIR3074 Gene

No data available for Paralogs for MIR3074 Gene

Variants for MIR3074 Gene

Sequence variations from dbSNP and Humsavar for MIR3074 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs35322368 -- 95,087,845(+) CCAAG(C/T)TGGGC upstream-variant-2KB
rs73654514 -- 95,087,856(+) TGAGC(A/C)TGAGT upstream-variant-2KB
rs73654515 -- 95,087,985(+) GCCTT(C/G)GTCTC upstream-variant-2KB
rs148876344 -- 95,087,998(+) GAACT(C/G)TCTTT upstream-variant-2KB
rs183117783 -- 95,087,994(+) TCCAG(A/T)ACTCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3074 Gene

Variant ID Type Subtype PubMed ID
nsv831656 CNV Loss 17160897

Relevant External Links for MIR3074 Gene

HapMap Linkage Disequilibrium report
MIR3074

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR3074 Gene

Disorders for MIR3074 Gene

No disorders were found for MIR3074 Gene.

No data available for UniProtKB/Swiss-Prot for MIR3074 Gene

Publications for MIR3074 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR3074 Gene

Sources for MIR3074 Gene

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