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Aliases for MIR302C Gene

Subcategory (RNA class) for MIR302C Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR302C Gene

  • MicroRNA 302c 2 3 5
  • Hsa-Mir-302c 3
  • Mir-302c 3
  • MIRN302C 3

External Ids for MIR302C Gene

Previous HGNC Symbols for MIR302C Gene

  • MIRN302C

Previous GeneCards Identifiers for MIR302C Gene

  • GC04M113798
  • GC04M113572
  • GC04M113576
  • GC04M113585

Summaries for MIR302C Gene

Entrez Gene Summary for MIR302C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR302C Gene

MIR302C (MicroRNA 302c) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR302C Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR302C

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR302C Gene

Genomics for MIR302C Gene

Regulatory Elements for MIR302C Gene


Promoters for MIR302C Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR302C on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR302C Gene

Chromosome:
4
Start:
112,648,363 bp from pter
End:
112,648,430 bp from pter
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR302C Gene

Genes around MIR302C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR302C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR302C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR302C Gene

ORGUL Member Location for MIR302C Gene

ORGUL Member Location for MIR302C gene

Proteins for MIR302C Gene

Post-translational modifications for MIR302C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR302C Gene

Domains & Families for MIR302C Gene

Gene Families for MIR302C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR302C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR302C Gene

Function for MIR302C Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR302C Gene

Localization for MIR302C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR302C Gene

Pathways & Interactions for MIR302C Gene

SuperPathways for MIR302C Gene

No Data Available

Interacting Proteins for MIR302C Gene

Gene Ontology (GO) - Biological Process for MIR302C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR302C Gene

Drugs & Compounds for MIR302C Gene

No Compound Related Data Available

Transcripts for MIR302C Gene

fRNAdb Secondary structures for MIR302C Gene

  • FR041335
  • hsa-mir-302c_MI0000773_Homo_sapiens_miR-302c_stem-loop_hairpin

mRNA/cDNA for MIR302C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR302C Gene

No ASD Table

Relevant External Links for MIR302C Gene

GeneLoc Exon Structure for
MIR302C
ECgene alternative splicing isoforms for
MIR302C

Expression for MIR302C Gene

mRNA expression in normal human tissues for MIR302C Gene

genes like me logo Genes that share expression patterns with MIR302C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR302C Gene

Orthologs for MIR302C Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR302C Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-302c 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-302c 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-302c 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir302c 36
  • 93 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 95 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-302c 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-302c 36
  • 89 (a)
OneToOne
Species with no ortholog for MIR302C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR302C Gene

ENSEMBL:
Gene Tree for MIR302C (if available)
TreeFam:
Gene Tree for MIR302C (if available)

Paralogs for MIR302C Gene

No data available for Paralogs for MIR302C Gene

Variants for MIR302C Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR302C Gene

Variant ID Type Subtype PubMed ID
nsv525715 CNV Loss 19592680

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR302C Gene

Disorders for MIR302C Gene

Relevant External Links for MIR302C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR302C

No disorders were found for MIR302C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR302C Gene

Publications for MIR302C Gene

  1. Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop. (PMID: 26199092) Chen L. … Gu J. (Cancer Res. 2015) 3 67
  2. Human embryonic stem cells express a unique set of microRNAs. (PMID: 15183728) Suh M.R. … Kim K.S. (Dev. Biol. 2004) 1 3
  3. MiR-302c inhibits tumor growth of hepatocellular carcinoma by suppressing the endothelial-mesenchymal transition of endothelial cells. (PMID: 25027009) Zhu K. … Zhou J. (Sci Rep 2014) 3
  4. MicroRNA-302 induces proliferation and inhibits oxidant-induced cell death in human adipose tissue-derived mesenchymal stem cells. (PMID: 25144720) Kim J.Y. … Jung J.S. (Cell Death Dis 2014) 3
  5. MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells. (PMID: 22511267) Dolezalova D. … Hampl A. (Stem Cells 2012) 3

Products for MIR302C Gene

Sources for MIR302C Gene

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