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Aliases for MIR302B Gene

Subcategory (RNA class) for MIR302B Gene

miRNA

Quality Score for this RNA gene is

8.2

Aliases for MIR302B Gene

  • MicroRNA 302b 2 3
  • Hsa-Mir-302b 3
  • MIRN302B 3

External Ids for MIR302B Gene

Previous Symbols for MIR302B Gene

  • MIRN302B

Summaries for MIR302B Gene

Entrez Gene Summary for MIR302B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR302B Gene

MIR302B (MicroRNA 302b) is a RNA Gene, and belongs to miRNA RNA class.

fRNAdb sequence ontologies for MIR302B Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR302B

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR302B Gene

Genomics for MIR302B Gene

Genomic Location for MIR302B Gene

Start:
112,648,485 bp from pter
End:
112,648,557 bp from pter
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR302B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR302B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR302B Gene

ORGUL Member Location for MIR302B Gene

ORGUL Member Location for MIR302B gene

No data available for Regulatory Elements for MIR302B Gene

Proteins for MIR302B Gene

Post-translational modifications for MIR302B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR302B Gene

Domains for MIR302B Gene

Gene Families for MIR302B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR302B: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR302B Gene

Function for MIR302B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR302B Gene

Localization for MIR302B Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR302B Gene

Pathways for MIR302B Gene

SuperPathways for MIR302B Gene

No Data Available

Interacting Proteins for MIR302B Gene

Gene Ontology (GO) - Biological Process for MIR302B Gene

None

No data available for Pathways by source for MIR302B Gene

Transcripts for MIR302B Gene

fRNAdb Secondary structures for MIR302B Gene

  • hsa-miR-302b-3p_MIMAT0000715_Homo_sapiens_miR-302b-3p_mature

mRNA/cDNA for MIR302B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR302B Gene

No ASD Table

Relevant External Links for MIR302B Gene

GeneLoc Exon Structure for
MIR302B
ECgene alternative splicing isoforms for
MIR302B

Expression for MIR302B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with MIR302B: view

Orthologs for MIR302B Gene

Evolution for MIR302B Gene

ENSEMBL:
Gene Tree for MIR302B (if available)
TreeFam:
Gene Tree for MIR302B (if available)

No data available for Orthologs for MIR302B Gene

Paralogs for MIR302B Gene

No data available for Paralogs for MIR302B Gene

Variants for MIR302B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR302B Gene

Variant ID Type Subtype PubMed ID
nsv525715 CNV Loss 19592680

Relevant External Links for MIR302B Gene

HapMap Linkage Disequilibrium report
MIR302B

No data available for Sequence variations from dbSNP and Humsavar for MIR302B Gene

Disorders for MIR302B Gene

No disorders were found for MIR302B Gene.

No data available for UniProtKB/Swiss-Prot for MIR302B Gene

Publications for MIR302B Gene

  1. Human embryonic stem cells express a unique set of microRNAs. (PMID: 15183728) Suh M.R. … Kim K.S. (Dev. Biol. 2004) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression. (PMID: 18930031) Lee N.S. … Kim K.S. (Biochem. Biophys. Res. Commun. 2008) 3
  5. miR-497 and miR-302b regulate ethanol-induced neuronal cell death through BCL2 protein and cyclin D2. (PMID: 21878650) Yadav S. … Parmar D. (J. Biol. Chem. 2011) 3

Products for MIR302B Gene

Sources for MIR302B Gene

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