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Aliases for MIR302B Gene

Subcategory (RNA class) for MIR302B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR302B Gene

  • MicroRNA 302b 2 3 5
  • Hsa-Mir-302b 3
  • Mir-302b 3
  • MIRN302B 3

External Ids for MIR302B Gene

Previous HGNC Symbols for MIR302B Gene

  • MIRN302B

Previous GeneCards Identifiers for MIR302B Gene

  • GC04M113799
  • GC04M113573
  • GC04M113577
  • GC04M113568
  • GC04M112651
  • GC04M112655

Summaries for MIR302B Gene

Entrez Gene Summary for MIR302B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR302B Gene

MIR302B (MicroRNA 302b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR302B Gene

Genomics for MIR302B Gene

Regulatory Elements for MIR302B Gene

Enhancers for MIR302B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F112704 0.5 Ensembl ENCODE 24.9 -56.0 -55983 2.9 PKNOX1 ZNF76 KLF17 FEZF1 ZNF2 GLIS2 ZNF366 SCRT2 KLF7 ZNF391 MIR302B MIR302A MIR302C MIR302D MIR367 LARP7 RPL7AP30 ZGRF1 ENSG00000250046 WRBP1
GH04F113546 1.3 Ensembl ENCODE 12.5 -897.8 -897839 2.1 PKNOX1 WRNIP1 ARID4B SIN3A FEZF1 ZNF2 YY1 CBX5 ZNF143 ZNF207 MIR302B GC04M113521 GC04P113443 PIR57694
GH04F112746 0.7 ENCODE 11.1 -100.2 -100207 7.2 BRD4 CTCF TEAD4 ZNF101 ETS1 ZNF316 GATA3 ZBTB48 POLR2A FOS ZGRF1 LOC105377371 LARP7 MIR302A MIR302C MIR302D MIR367 MIR302B GC04M112739 ENSG00000202536
GH04F112100 0.5 ENCODE 10.5 +550.0 549982 0.1 CTCF ARNT SAP130 ZNF384 RAD21 ZNF2 FOXK2 SCRT2 MIXL1 SCRT1 C4orf32 MIR302B RPS12P8 TUBB8P3
GH04F112099 0.4 ENCODE 10.5 +550.2 550202 0.1 CTCF ARNT SAP130 ZNF384 ZNF2 RAD21 FOXK2 SCRT2 SMC3 MIXL1 C4orf32 MIR302B RPS12P8 TUBB8P3
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR302B on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR302B Gene

Chromosome:
4
Start:
112,646,476 bp from pter
End:
112,650,051 bp from pter
Size:
3,576 bases
Orientation:
Minus strand

Genomic View for MIR302B Gene

Genes around MIR302B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR302B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR302B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR302B Gene

Proteins for MIR302B Gene

Post-translational modifications for MIR302B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR302B Gene

Domains & Families for MIR302B Gene

Gene Families for MIR302B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR302B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR302B Gene

Function for MIR302B Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR302B Gene

Localization for MIR302B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR302B Gene

Pathways & Interactions for MIR302B Gene

SuperPathways for MIR302B Gene

No Data Available

Interacting Proteins for MIR302B Gene

Gene Ontology (GO) - Biological Process for MIR302B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR302B Gene

Transcripts for MIR302B Gene

mRNA/cDNA for MIR302B Gene

(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR302B Gene

No ASD Table

Relevant External Links for MIR302B Gene

GeneLoc Exon Structure for
MIR302B
ECgene alternative splicing isoforms for
MIR302B

Expression for MIR302B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR302B Gene:

MIR302B
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR302B Gene

Orthologs for MIR302B Gene

Evolution for MIR302B Gene

ENSEMBL:
Gene Tree for MIR302B (if available)
TreeFam:
Gene Tree for MIR302B (if available)

No data available for Orthologs for MIR302B Gene

Paralogs for MIR302B Gene

No data available for Paralogs for MIR302B Gene

Variants for MIR302B Gene

Sequence variations from dbSNP and Humsavar for MIR302B Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs111474331 -- 112,650,347(+) AAATA(C/T)GTTTT intron-variant, upstream-variant-2KB
rs112220956 -- 112,649,884(+) TTTAA(A/C)ACAAT intron-variant, upstream-variant-2KB
rs114318553 -- 112,648,539(+) TTCCA(G/T)GTTAA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs115879346 -- 112,648,075(+) GGGGG(C/T)CCCTT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs118095673 -- 112,649,722(+) ATAAT(A/G)TACTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR302B Gene

Variant ID Type Subtype PubMed ID
nsv1006030 CNV gain 25217958
nsv1014926 CNV gain 25217958
nsv525715 CNV loss 19592680

Relevant External Links for MIR302B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR302B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR302B Gene

Disorders for MIR302B Gene

Relevant External Links for MIR302B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR302B

No disorders were found for MIR302B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR302B Gene

Publications for MIR302B Gene

  1. miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response. (PMID: 26623722) Cataldo A. … Croce C.M. (Oncotarget 2016) 3 64
  2. MicroRNA-302 induces proliferation and inhibits oxidant-induced cell death in human adipose tissue-derived mesenchymal stem cells. (PMID: 25144720) Kim J.Y. … Jung J.S. (Cell Death Dis 2014) 3 64
  3. miR-302b is a potential molecular marker of esophageal squamous cell carcinoma and functions as a tumor suppressor by targeting ErbB4. (PMID: 24438167) Zhang M. … Wang J. (J. Exp. Clin. Cancer Res. 2014) 3 64
  4. Increased sensitivity to chemotherapy induced by CpG-ODN treatment is mediated by microRNA modulation. (PMID: 23484053) De Cecco L. … Balsari A. (PLoS ONE 2013) 3 64
  5. MicroRNA-302b suppresses cell proliferation by targeting EGFR in human hepatocellular carcinoma SMMC-7721 cells. (PMID: 24083596) Wang L. … Huang C. (BMC Cancer 2013) 3 64

Products for MIR302B Gene

Sources for MIR302B Gene

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