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Aliases for MIR29C Gene

Subcategory (RNA class) for MIR29C Gene

miRNA

Quality Score for this RNA gene is

10.2

Aliases for MIR29C Gene

  • MicroRNA 29c 2 3 5
  • Hsa-Mir-29c 3
  • MiRNA29C 3
  • Mir-29c 3
  • MIRN29C 3

External Ids for MIR29C Gene

Previous HGNC Symbols for MIR29C Gene

  • MIRN29C

Previous GeneCards Identifiers for MIR29C Gene

  • GC01M206043
  • GC01M207975

Summaries for MIR29C Gene

Entrez Gene Summary for MIR29C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR29C Gene

MIR29C (MicroRNA 29c) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

fRNAdb sequence ontologies for MIR29C Gene - the ORGUL cluster for this gene includes several descriptions:

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR29C

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR29C Gene

Genomics for MIR29C Gene

Genomic Location for MIR29C Gene

Chromosome:
1
Start:
207,801,845 bp from pter
End:
207,801,956 bp from pter
Size:
112 bases
Orientation:
Minus strand

Genomic View for MIR29C Gene

Genes around MIR29C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR29C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR29C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR29C Gene

ORGUL Member Location for MIR29C Gene

ORGUL Member Location for MIR29C gene

No data available for Regulatory Elements for MIR29C Gene

Proteins for MIR29C Gene

Post-translational modifications for MIR29C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR29C Gene

Domains & Families for MIR29C Gene

Gene Families for MIR29C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR29C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR29C Gene

Function for MIR29C Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR29C Gene

Localization for MIR29C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR29C Gene

Pathways & Interactions for MIR29C Gene

genes like me logo Genes that share pathways with MIR29C: view

Pathways by source for MIR29C Gene

1 BioSystems pathway for MIR29C Gene
1 KEGG pathway for MIR29C Gene

Interacting Proteins for MIR29C Gene

Gene Ontology (GO) - Biological Process for MIR29C Gene

None

No data available for SIGNOR curated interactions for MIR29C Gene

Drugs & Compounds for MIR29C Gene

No Compound Related Data Available

Transcripts for MIR29C Gene

fRNAdb Secondary structures for MIR29C Gene

  • FR390016
  • FR185304

mRNA/cDNA for MIR29C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR29C Gene

No ASD Table

Relevant External Links for MIR29C Gene

GeneLoc Exon Structure for
MIR29C
ECgene alternative splicing isoforms for
MIR29C

Expression for MIR29C Gene

mRNA expression in normal human tissues for MIR29C Gene

genes like me logo Genes that share expression patterns with MIR29C: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR29C Gene

Orthologs for MIR29C Gene

Evolution for MIR29C Gene

ENSEMBL:
Gene Tree for MIR29C (if available)
TreeFam:
Gene Tree for MIR29C (if available)

No data available for Orthologs for MIR29C Gene

Paralogs for MIR29C Gene

No data available for Paralogs for MIR29C Gene

Variants for MIR29C Gene

Relevant External Links for MIR29C Gene

HapMap Linkage Disequilibrium report
MIR29C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR29C Gene

Disorders for MIR29C Gene

Relevant External Links for MIR29C

Human Genome Epidemiology (HuGE) Navigator
MIR29C
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR29C

No disorders were found for MIR29C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR29C Gene

Publications for MIR29C Gene

  1. MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1. (PMID: 24870620) Han T.S. … Yang H.K. (Gut 2015) 3
  2. miR-29c suppresses pancreatic cancer liver metastasis in an orthotopic implantation model in nude mice and affects survival in pancreatic cancer patients. (PMID: 25863127) Zou Y. … Chen J. (Carcinogenesis 2015) 3
  3. MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma. (PMID: 23728341) Bae H.J. … Nam S.W. (Oncogene 2014) 3
  4. Dysregulation of microRNA expression drives aberrant DNA hypermethylation in basal-like breast cancer. (PMID: 24297604) Sandhu R. … Coleman W.B. (Int. J. Oncol. 2014) 3
  5. Expression of miR-29c, miR-93, and miR-429 as potential biomarkers for detection of early stage non-small lung cancer. (PMID: 24523873) Zhu W. … Le H. (PLoS ONE 2014) 3

Products for MIR29C Gene

Sources for MIR29C Gene

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