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Aliases for MIR29C Gene

Subcategory (RNA class) for MIR29C Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR29C Gene

  • MicroRNA 29c 2 3
  • Chromosome 1 Open Reading Frame 132 5
  • Hsa-Mir-29c 3
  • C1orf132 5
  • MiRNA29C 3
  • Mir-29c 3
  • MIRN29C 3

External Ids for MIR29C Gene

Previous HGNC Symbols for MIR29C Gene

  • MIRN29C

Previous GeneCards Identifiers for MIR29C Gene

  • GC01M206043
  • GC01M207975

Summaries for MIR29C Gene

Entrez Gene Summary for MIR29C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR29C Gene

MIR29C (MicroRNA 29c) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR29C Gene

Genomics for MIR29C Gene

Regulatory Elements for MIR29C Gene

Enhancers for MIR29C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F207816 1.8 FANTOM5 Ensembl ENCODE 12 +56.2 56223 12.5 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF302 CD46 MIR29B2 MIR29C C1orf132 CD34 CR1 PLXNA2 CR1L PIR33548 GC01P207829
GH01F207846 1.6 FANTOM5 Ensembl ENCODE 12.9 +28.5 28501 7.6 PKNOX1 ARNT CREB3L1 SIN3A ZNF2 ZNF302 FOS DEK ZNF263 MCM3 CD46 LINC01717 MIR29B2 C1orf132 MIR29C CD34 CR1L PLXNA2 CR1 PIR33548
GH01F207747 1.7 FANTOM5 Ensembl ENCODE 11.6 +128.0 127961 6.8 HDGF PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 YBX1 ZNF2 YY1 CD46 MIR29C MIR29B2 C1orf132 CR1L GC01P207741
GH01F207941 1.3 FANTOM5 Ensembl ENCODE 10.7 -63.1 -63139 1.9 SAP130 JUN ZMYM3 MAX THRB TEAD3 RARA ZFHX2 POLR2A NR2F6 CD34 MIR29C MIR29B2 C1orf132 PLXNA2 LOC105372883
GH01F207649 1.4 FANTOM5 ENCODE 9.4 +229.1 229148 1.8 HDGF PKNOX1 ARNT SIN3A DMAP1 FEZF1 YY1 ZNF302 ZNF143 ZNF207 CR1L CDCA4P4 C4BPA MIR29B2 MIR29C C1orf132 CR2 CDCA4P3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR29C on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR29C Gene

Chromosome:
1
Start:
207,801,518 bp from pter
End:
207,879,096 bp from pter
Size:
77,579 bases
Orientation:
Minus strand

Genomic View for MIR29C Gene

Genes around MIR29C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR29C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR29C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR29C Gene

Proteins for MIR29C Gene

Post-translational modifications for MIR29C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR29C Gene

Domains & Families for MIR29C Gene

Gene Families for MIR29C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR29C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR29C Gene

Function for MIR29C Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR29C Gene

Localization for MIR29C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR29C Gene

Pathways & Interactions for MIR29C Gene

SuperPathways for MIR29C Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR29C: view

Pathways by source for MIR29C Gene

1 KEGG pathway for MIR29C Gene

Interacting Proteins for MIR29C Gene

Gene Ontology (GO) - Biological Process for MIR29C Gene

None

No data available for SIGNOR curated interactions for MIR29C Gene

Transcripts for MIR29C Gene

mRNA/cDNA for MIR29C Gene

(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR29C Gene

No ASD Table

Relevant External Links for MIR29C Gene

GeneLoc Exon Structure for
MIR29C
ECgene alternative splicing isoforms for
MIR29C

Expression for MIR29C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR29C Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR29C Gene:

MIR29C
genes like me logo Genes that share expression patterns with MIR29C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR29C Gene

Orthologs for MIR29C Gene

Evolution for MIR29C Gene

ENSEMBL:
Gene Tree for MIR29C (if available)
TreeFam:
Gene Tree for MIR29C (if available)

No data available for Orthologs for MIR29C Gene

Paralogs for MIR29C Gene

No data available for Paralogs for MIR29C Gene

Variants for MIR29C Gene

Sequence variations from dbSNP and Humsavar for MIR29C Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111835874 -- 207,801,780(+) CTCTG(C/T)CCATC nc-transcript-variant, downstream-variant-500B
rs112843452 -- 207,802,093(+) ACTGC(C/T)CTCTC nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB
rs112946570 -- 207,803,733(+) ACTAC(A/G)TAACA intron-variant, upstream-variant-2KB
rs113264076 -- 207,801,622(+) CAGCA(C/T)TACAT nc-transcript-variant, downstream-variant-500B
rs113405911 -- 207,803,763(+) CAGGA(A/G)CATCA intron-variant, upstream-variant-2KB

Relevant External Links for MIR29C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR29C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR29C Gene

Disorders for MIR29C Gene

Relevant External Links for MIR29C

Human Genome Epidemiology (HuGE) Navigator
MIR29C
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR29C

No disorders were found for MIR29C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR29C Gene

Publications for MIR29C Gene

  1. Cell-derived microvesicles mediate the delivery of miR-29a/c to suppress angiogenesis in gastric carcinoma. (PMID: 27000664) Zhang H. … Ba Y. (Cancer Lett. 2016) 3 64
  2. miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53-p21 and p16-pRB pathways. (PMID: 26792405) Shang J. … Zhou Y. (Biochim. Biophys. Acta 2016) 3 64
  3. MiR-29c regulates the expression of miR-34c and miR-449a by targeting DNA methyltransferase 3a and 3b in nasopharyngeal carcinoma. (PMID: 26975503) Niu M. … Peng S. (BMC Cancer 2016) 3 64
  4. Neuro-Epigenetic Indications of Acute Stress Response in Humans: The Case of MicroRNA-29c. (PMID: 26730965) Vaisvaser S. … Hendler T. (PLoS ONE 2016) 3 64
  5. Downregulated miR-29c correlates with increased BACE1 expression in sporadic Alzheimer's disease. (PMID: 25973041) Lei X. … Cheng Y. (Int J Clin Exp Pathol 2015) 3 64

Products for MIR29C Gene

Sources for MIR29C Gene

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