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Aliases for MIR29B2 Gene

Subcategory (RNA class) for MIR29B2 Gene


Quality Score for this RNA gene is


Aliases for MIR29B2 Gene

  • MicroRNA 29b-2 2 3
  • Chromosome 1 Open Reading Frame 132 5
  • Hsa-Mir-29b-2 3
  • Mir-29b-2 3
  • MIRN29B2 3
  • C1orf132 5
  • MiR-29b 3

External Ids for MIR29B2 Gene

Previous HGNC Symbols for MIR29B2 Gene

  • MIRN29B2

Previous GeneCards Identifiers for MIR29B2 Gene

  • GC01M206044
  • GC01M207976
  • GC01M207977
  • GC01M207984

Summaries for MIR29B2 Gene

Entrez Gene Summary for MIR29B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR29B2 Gene

MIR29B2 (MicroRNA 29b-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR29B2 Gene

Genomics for MIR29B2 Gene

Regulatory Elements for MIR29B2 Gene

Enhancers for MIR29B2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F207816 1.8 FANTOM5 Ensembl ENCODE 12 +56.2 56223 12.5 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF302 CD46 C1orf132 MIR29B2 MIR29C CD34 CR1 PLXNA2 CR1L GC01P207829 PIR33548
GH01F207846 1.6 FANTOM5 Ensembl ENCODE 12.9 +28.5 28501 7.6 PKNOX1 ARNT CREB3L1 SIN3A ZNF2 ZNF302 FOS DEK ZNF263 MCM3 CD46 LINC01717 C1orf132 MIR29C MIR29B2 CD34 CR1L PLXNA2 CR1 PIR33548
GH01F207747 1.7 FANTOM5 Ensembl ENCODE 10.4 +128.0 127961 6.8 HDGF PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 YBX1 ZNF2 YY1 CD46 MIR29C MIR29B2 C1orf132 CR1L GC01P207741
GH01F207941 1.3 FANTOM5 Ensembl ENCODE 10.3 -63.1 -63139 1.9 SAP130 JUN ZMYM3 MAX THRB TEAD3 RARA ZFHX2 POLR2A NR2F6 CD34 MIR29C MIR29B2 C1orf132 PLXNA2 LOC105372883
GH01F207649 1.4 FANTOM5 ENCODE 9.4 +229.1 229148 1.8 HDGF PKNOX1 ARNT SIN3A DMAP1 FEZF1 YY1 ZNF302 ZNF143 ZNF207 CR1L CDCA4P4 C4BPA MIR29B2 MIR29C C1orf132 CR2 CDCA4P3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR29B2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR29B2 Gene

207,801,518 bp from pter
207,879,096 bp from pter
77,579 bases
Minus strand

Genomic View for MIR29B2 Gene

Genes around MIR29B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR29B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR29B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR29B2 Gene

Proteins for MIR29B2 Gene

Post-translational modifications for MIR29B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR29B2 Gene

Domains & Families for MIR29B2 Gene

Gene Families for MIR29B2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR29B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR29B2 Gene

Function for MIR29B2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR29B2 Gene

Localization for MIR29B2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR29B2 Gene

Pathways & Interactions for MIR29B2 Gene

SuperPathways for MIR29B2 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR29B2: view

Pathways by source for MIR29B2 Gene

1 KEGG pathway for MIR29B2 Gene

Interacting Proteins for MIR29B2 Gene

Gene Ontology (GO) - Biological Process for MIR29B2 Gene


No data available for SIGNOR curated interactions for MIR29B2 Gene

Transcripts for MIR29B2 Gene

mRNA/cDNA for MIR29B2 Gene

(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR29B2 Gene

No ASD Table

Relevant External Links for MIR29B2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR29B2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR29B2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR29B2 Gene:

genes like me logo Genes that share expression patterns with MIR29B2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR29B2 Gene

Orthologs for MIR29B2 Gene

Evolution for MIR29B2 Gene

Gene Tree for MIR29B2 (if available)
Gene Tree for MIR29B2 (if available)

No data available for Orthologs for MIR29B2 Gene

Paralogs for MIR29B2 Gene

No data available for Paralogs for MIR29B2 Gene

Variants for MIR29B2 Gene

Sequence variations from dbSNP and Humsavar for MIR29B2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs112843452 -- 207,802,093(+) ACTGC(C/T)CTCTC nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB
rs112946570 -- 207,803,733(+) ACTAC(A/G)TAACA intron-variant, upstream-variant-2KB
rs113405911 -- 207,803,763(+) CAGGA(A/G)CATCA intron-variant, upstream-variant-2KB
rs114724166 -- 207,803,732(+) GACTA(A/C)ATAAC intron-variant, upstream-variant-2KB
rs114790693 -- 207,802,623(+) TGACA(C/T)AGTGC nc-transcript-variant, upstream-variant-2KB

Relevant External Links for MIR29B2 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR29B2 Gene

Disorders for MIR29B2 Gene

Relevant External Links for MIR29B2

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR29B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR29B2 Gene

Publications for MIR29B2 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 46 64
  2. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 46 64
  3. MicroRNA 29 targets nuclear factor-I_B-repressing factor and Claudin 1 to increase intestinal permeability. (PMID: 25277410) Zhou Q. … Verne G.N. (Gastroenterology 2015) 3 64
  4. Expression and functional role of miR-29b in renal cell carcinoma. (PMID: 26823729) Xu Y. … Tong Y. (Int J Clin Exp Pathol 2015) 3 64
  5. microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway. (PMID: 25356754) Wang J. … Yu J. (Oncotarget 2015) 3 64

Products for MIR29B2 Gene

Sources for MIR29B2 Gene

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