Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR29B1 Gene

Subcategory (RNA class) for MIR29B1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR29B1 Gene

  • MicroRNA 29b-1 2 3
  • Hsa-Mir-29b-1 3
  • MicroRNA 29a 5
  • MiRNA29B1 3
  • Mir-29b-1 3
  • MIRN29B1 3
  • MiR-29b 3
  • MIR29A 5

External Ids for MIR29B1 Gene

Previous HGNC Symbols for MIR29B1 Gene

  • MIRN29B1

Previous GeneCards Identifiers for MIR29B1 Gene

  • GC07M130215
  • GC07M130562

Summaries for MIR29B1 Gene

Entrez Gene Summary for MIR29B1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR29B1 Gene

MIR29B1 (MicroRNA 29b-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR29B1 Gene

Genomics for MIR29B1 Gene

Regulatory Elements for MIR29B1 Gene

Enhancers for MIR29B1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR29B1 on UCSC Golden Path with GeneCards custom track

Promoters for MIR29B1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MIR29B1 Gene

Chromosome:
7
Start:
130,876,747 bp from pter
End:
130,913,310 bp from pter
Size:
36,564 bases
Orientation:
Minus strand

Genomic View for MIR29B1 Gene

Genes around MIR29B1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR29B1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR29B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR29B1 Gene

ORGUL Member Location for MIR29B1 Gene

ORGUL Member Location for MIR29B1 gene

Proteins for MIR29B1 Gene

Post-translational modifications for MIR29B1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR29B1 Gene

Domains & Families for MIR29B1 Gene

Gene Families for MIR29B1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR29B1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR29B1 Gene

Function for MIR29B1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR29B1 Gene

Localization for MIR29B1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR29B1 Gene

Pathways & Interactions for MIR29B1 Gene

genes like me logo Genes that share pathways with MIR29B1: view

Pathways by source for MIR29B1 Gene

1 BioSystems pathway for MIR29B1 Gene
1 KEGG pathway for MIR29B1 Gene

Interacting Proteins for MIR29B1 Gene

Gene Ontology (GO) - Biological Process for MIR29B1 Gene

None

No data available for SIGNOR curated interactions for MIR29B1 Gene

Drugs & Compounds for MIR29B1 Gene

No Compound Related Data Available

Transcripts for MIR29B1 Gene

mRNA/cDNA for MIR29B1 Gene

(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR29B1 Gene

No ASD Table

Relevant External Links for MIR29B1 Gene

GeneLoc Exon Structure for
MIR29B1
ECgene alternative splicing isoforms for
MIR29B1

Expression for MIR29B1 Gene

mRNA expression in normal human tissues for MIR29B1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR29B1 Gene:

MIR29B1
genes like me logo Genes that share expression patterns with MIR29B1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR29B1 Gene

Orthologs for MIR29B1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR29B1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-29a 35
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-29a 35
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-29a-1 35
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir29a 35
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-29a-1 35
  • 59 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-29a 35
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-29a 35
  • 82 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-29a-1 35
  • 56 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CR749762.2 35
  • 62 (a)
OneToOne
Species where no ortholog for MIR29B1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR29B1 Gene

ENSEMBL:
Gene Tree for MIR29B1 (if available)
TreeFam:
Gene Tree for MIR29B1 (if available)

Paralogs for MIR29B1 Gene

No data available for Paralogs for MIR29B1 Gene

Variants for MIR29B1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR29B1 Gene

Variant ID Type Subtype PubMed ID
nsv608422 CNV gain 21841781

Relevant External Links for MIR29B1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR29B1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR29B1 Gene

Disorders for MIR29B1 Gene

Relevant External Links for MIR29B1

Genetic Association Database (GAD)
MIR29B1
Human Genome Epidemiology (HuGE) Navigator
MIR29B1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR29B1

No disorders were found for MIR29B1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR29B1 Gene

Publications for MIR29B1 Gene

  1. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 46 65
  2. Activated mineralocorticoid receptor regulates micro-RNA-29b in vascular smooth muscle cells. (PMID: 26728178) Bretschneider M. … Grossmann C. (FASEB J. 2016) 3 65
  3. c-Myc suppresses microRNA-29b to promote tumor aggressiveness and poor outcomes in non-small cell lung cancer by targeting FHIT. (PMID: 24909176) Wu D.W. … Lee H. (Oncogene 2015) 3 65
  4. MiR-29b replacement inhibits proteasomes and disrupts aggresome+autophagosome formation to enhance the antimyeloma benefit of bortezomib. (PMID: 25234165) Jagannathan S. … Driscoll J.J. (Leukemia 2015) 3 65
  5. MicroRNA 29 targets nuclear factor-I_B-repressing factor and Claudin 1 to increase intestinal permeability. (PMID: 25277410) Zhou Q. … Verne G.N. (Gastroenterology 2015) 3 65

Products for MIR29B1 Gene

Sources for MIR29B1 Gene

Content
Loading form....