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Aliases for MIR29B1 Gene

Subcategory (RNA class) for MIR29B1 Gene

lncRNA

Quality Score for this RNA gene is

3

Aliases for MIR29B1 Gene

  • MicroRNA 29b-1 2 3
  • MIRN29B1 3 6
  • Hsa-Mir-29b-1 3
  • MiRNA29B1 3

External Ids for MIR29B1 Gene

ORGUL Members for MIR29B1 Gene

Previous HGNC Symbols for MIR29B1 Gene

  • MIRN29B1

Previous GeneCards Identifiers for MIR29B1 Gene

  • GC07M130215
  • GC07M130562

Summaries for MIR29B1 Gene

Entrez Gene Summary for MIR29B1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR29B1 Gene

MIR29B1 (MicroRNA 29b-1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with MIR29B1 include familial breast cancer and multiple myeloma. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR29B1 Gene

Genomics for MIR29B1 Gene

Genomic Location for MIR29B1 Gene

Start:
130,877,459 bp from pter
End:
130,877,539 bp from pter
Size:
81 bases
Orientation:
Minus strand

Genomic View for MIR29B1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR29B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR29B1 Gene

No data available for Regulatory Elements for MIR29B1 Gene

Proteins for MIR29B1 Gene

Post-translational modifications for MIR29B1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR29B1 Gene

Domains for MIR29B1 Gene

Gene Families for MIR29B1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR29B1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR29B1 Gene

Function for MIR29B1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR29B1 Gene

Localization for MIR29B1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR29B1 Gene

Pathways for MIR29B1 Gene

genes like me logo Genes that share pathways with MIR29B1: view

Pathways by source for MIR29B1 Gene

1 BioSystems pathway for MIR29B1 Gene
1 KEGG pathway for MIR29B1 Gene

Interacting Proteins for MIR29B1 Gene

Gene Ontology (GO) - Biological Process for MIR29B1 Gene

None

Transcripts for MIR29B1 Gene

mRNA/cDNA for MIR29B1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR29B1 Gene

No ASD Table

Relevant External Links for MIR29B1 Gene

GeneLoc Exon Structure for
MIR29B1
ECgene alternative splicing isoforms for
MIR29B1

Expression for MIR29B1 Gene

mRNA expression in normal human tissues for MIR29B1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with MIR29B1: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR29B1 Gene

Orthologs for MIR29B1 Gene

Evolution for MIR29B1 Gene

ENSEMBL:
Gene Tree for MIR29B1 (if available)
TreeFam:
Gene Tree for MIR29B1 (if available)

No data available for Orthologs for MIR29B1 Gene

Paralogs for MIR29B1 Gene

No data available for Paralogs for MIR29B1 Gene

Variants for MIR29B1 Gene

Relevant External Links for MIR29B1 Gene

HapMap Linkage Disequilibrium report
MIR29B1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR29B1 Gene

Disorders for MIR29B1 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for MIR29B1 Gene in MalaCards »

(2) Diseases for MIR29B1 Gene including...

Relevant External Links for MIR29B1

Genetic Association Database (GAD)
MIR29B1
Human Genome Epidemiology (HuGE) Navigator
MIR29B1
genes like me logo Genes that share disorders with MIR29B1: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR29B1 Gene

Publications for MIR29B1 Gene

  1. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 48
  2. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. (PMID: 19211935) Garzon R. … Marcucci G. (Blood 2009) 3
  3. Role of miR-29b on the regulation of the extracellular matrix in human trabecular meshwork cells under chronic oxidative stress. (PMID: 19956414) Luna C. … Gonzalez P. (Mol. Vis. 2009) 3
  4. Epstein-Barr virus encoded LMP1 downregulates TCL1 oncogene through miR-29b. (PMID: 19966860) Anastasiadou E. … Trivedi P. (Oncogene 2010) 3
  5. MicroRNA-29b regulates the expression level of human progranulin, a secreted glycoprotein implicated in frontotemporal dementia. (PMID: 20479936) Jiao J. … Gao F.B. (PLoS ONE 2010) 3

Products for MIR29B1 Gene

Sources for MIR29B1 Gene

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