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Aliases for MIR29A Gene

Subcategory (RNA class) for MIR29A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR29A Gene

  • MicroRNA 29a 2 3
  • MicroRNA 29 2 3
  • Hsa-Mir-29a 3
  • Hsa-Mir-29 3
  • MiRNA29A 3
  • Mir-29a 3
  • MIRN29A 3
  • MIRN29 3

External Ids for MIR29A Gene

Previous HGNC Symbols for MIR29A Gene

  • MIRN29
  • MIRN29A

Previous GeneCards Identifiers for MIR29A Gene

  • GC07M130214
  • GC07M130561

Summaries for MIR29A Gene

Entrez Gene Summary for MIR29A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR29A Gene

MIR29A (MicroRNA 29a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR29A Gene

Genomics for MIR29A Gene

Genomic Location for MIR29A Gene

Chromosome:
7
Start:
130,876,735 bp from pter
End:
130,876,821 bp from pter
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR29A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR29A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR29A Gene

No data available for Regulatory Elements for MIR29A Gene

Proteins for MIR29A Gene

Post-translational modifications for MIR29A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR29A Gene

Domains & Families for MIR29A Gene

Gene Families for MIR29A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR29A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR29A Gene

Function for MIR29A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR29A Gene

Localization for MIR29A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR29A Gene

Pathways & Interactions for MIR29A Gene

genes like me logo Genes that share pathways with MIR29A: view

Pathways by source for MIR29A Gene

1 KEGG pathway for MIR29A Gene

Interacting Proteins for MIR29A Gene

Gene Ontology (GO) - Biological Process for MIR29A Gene

None

No data available for SIGNOR curated interactions for MIR29A Gene

Drugs & Compounds for MIR29A Gene

No Compound Related Data Available

Transcripts for MIR29A Gene

mRNA/cDNA for MIR29A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR29A Gene

No ASD Table

Relevant External Links for MIR29A Gene

GeneLoc Exon Structure for
MIR29A
ECgene alternative splicing isoforms for
MIR29A

Expression for MIR29A Gene

mRNA expression in normal human tissues for MIR29A Gene

genes like me logo Genes that share expression patterns with MIR29A: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR29A Gene

Orthologs for MIR29A Gene

Evolution for MIR29A Gene

ENSEMBL:
Gene Tree for MIR29A (if available)
TreeFam:
Gene Tree for MIR29A (if available)

No data available for Orthologs for MIR29A Gene

Paralogs for MIR29A Gene

No data available for Paralogs for MIR29A Gene

Variants for MIR29A Gene

Sequence variations from dbSNP and Humsavar for MIR29A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs12671082 -- 130,876,442(+) ATCAT(A/C)TAAGC downstream-variant-500B
rs57826832 -- 130,876,587(+) ACATG(A/C)AATTC downstream-variant-500B
rs61545969 -- 130,876,632(+) GAAAA(A/G)TCACC downstream-variant-500B
rs111826474 -- 130,876,841(+) GAGGG(C/T)TGGGA upstream-variant-2KB
rs113362016 -- 130,876,543(+) CATTC(A/G)TGATA downstream-variant-500B

Relevant External Links for MIR29A Gene

HapMap Linkage Disequilibrium report
MIR29A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR29A Gene

Disorders for MIR29A Gene

Relevant External Links for MIR29A

Genetic Association Database (GAD)
MIR29A
Human Genome Epidemiology (HuGE) Navigator
MIR29A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR29A
genes like me logo Genes that share disorders with MIR29A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR29A Gene

Publications for MIR29A Gene

  1. Tumour-suppressive microRNA-29s directly regulate LOXL2 expression and inhibit cancer cell migration and invasion in renal cell carcinoma. (PMID: 26096783) Nishikawa R. … Seki N. (FEBS Lett. 2015) 67
  2. The role of miR-29 in pulmonary fibrosis. (PMID: 25454218) Cushing L. … LA1 J. (Biochem. Cell Biol. 2015) 67
  3. Overexpression of blood microRNAs 103a, 30b, and 29a in L-dopa-treated patients with PD. (PMID: 25596505) Serafin A. … Schwienbacher C. (Neurology 2015) 67
  4. miR-29a promotes scavenger receptor A expression by targeting QKI (quaking) during monocyte-macrophage differentiation. (PMID: 26056009) Wang S. … Zhu J. (Biochem. Biophys. Res. Commun. 2015) 67
  5. CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth. (PMID: 25241894) Mathsyaraja H. … Ostrowski M.C. (Oncogene 2015) 67

Products for MIR29A Gene

Sources for MIR29A Gene

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