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Aliases for MIR299 Gene

Subcategory (RNA class) for MIR299 Gene

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Quality Score for this RNA gene is

3

Aliases for MIR299 Gene

  • MicroRNA 299 2 3
  • Hsa-Mir-299 3
  • Mir-299 3
  • MIRN299 3

External Ids for MIR299 Gene

ORGUL Members for MIR299 Gene

Previous HGNC Symbols for MIR299 Gene

  • MIRN299

Previous GeneCards Identifiers for MIR299 Gene

  • GC14P100813
  • GC14P100905
  • GC14P101490
  • GC14P101232

Summaries for MIR299 Gene

Entrez Gene Summary for MIR299 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR299 Gene

MIR299 (MicroRNA 299) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR299 Gene

Genomics for MIR299 Gene

Genomic Location for MIR299 Gene

Chromosome:
14
Start:
101,023,780 bp from pter
End:
101,023,890 bp from pter
Size:
111 bases
Orientation:
Plus strand

Genomic View for MIR299 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR299 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR299 Gene

No data available for Regulatory Elements for MIR299 Gene

Proteins for MIR299 Gene

Post-translational modifications for MIR299 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR299 Gene

Domains & Families for MIR299 Gene

Gene Families for MIR299 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR299: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR299 Gene

Function for MIR299 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR299 Gene

Localization for MIR299 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR299 Gene

Pathways & Interactions for MIR299 Gene

SuperPathways for MIR299 Gene

No Data Available

Interacting Proteins for MIR299 Gene

Gene Ontology (GO) - Biological Process for MIR299 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR299 Gene

Drugs & Compounds for MIR299 Gene

No Compound Related Data Available

Transcripts for MIR299 Gene

mRNA/cDNA for MIR299 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR299 Gene

No ASD Table

Relevant External Links for MIR299 Gene

GeneLoc Exon Structure for
MIR299
ECgene alternative splicing isoforms for
MIR299

Expression for MIR299 Gene

mRNA expression in normal human tissues for MIR299 Gene

genes like me logo Genes that share expression patterns with MIR299: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR299 Gene

Orthologs for MIR299 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR299 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-299 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-299 36
  • 58 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25400 36
  • 55 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-299 36
  • 99 (a)
OneToOne
Species with no ortholog for MIR299:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR299 Gene

ENSEMBL:
Gene Tree for MIR299 (if available)
TreeFam:
Gene Tree for MIR299 (if available)

Paralogs for MIR299 Gene

No data available for Paralogs for MIR299 Gene

Variants for MIR299 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR299 Gene

Variant ID Type Subtype PubMed ID
nsv1426 CNV Insertion 18451855

Relevant External Links for MIR299 Gene

HapMap Linkage Disequilibrium report
MIR299

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR299 Gene

Disorders for MIR299 Gene

Relevant External Links for MIR299

Human Genome Epidemiology (HuGE) Navigator
MIR299
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR299
genes like me logo Genes that share disorders with MIR299: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR299 Gene

Publications for MIR299 Gene

  1. MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells. (PMID: 24166498) Formosa A. … Candi E. (Oncogene 2014) 67
  2. MicroRNA 299-3p modulates replicative senescence in endothelial cells. (PMID: 23362143) Jong H.L. … Wong P.F. (Physiol. Genomics 2013) 67
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 67
  4. Genetic polymorphisms in the precursor MicroRNA flanking region and non-small cell lung cancer survival. (PMID: 20889907) Hu Z. … Shen H. (Am. J. Respir. Crit. Care Med. 2011) 67
  5. Integrated analysis of microRNA and mRNA expression profiles in physiological myelopoiesis: role of hsa-mir-299-5p in CD34+ progenitor cells commitment. (PMID: 21364636) Tenedini E. … Ferrari S. (Cell Death Dis 2010) 67

Products for MIR299 Gene

Sources for MIR299 Gene

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