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MIR298 Gene(RNA Gene)

MicroRNA 298

GCID:
GC20M058818
GIFtS:
17
Genes Participants
UDN Logo

Aliases for MIR298 Gene

Subcategory (RNA class) for MIR298 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR298 Gene

  • MicroRNA 298 2 3 5
  • Hsa-Mir-298 3
  • MIRN298 3

External Ids for MIR298 Gene

ORGUL Members for MIR298 Gene

Previous HGNC Symbols for MIR298 Gene

  • MIRN298

Previous GeneCards Identifiers for MIR298 Gene

  • GC20M056836
  • GC20M056837
  • GC20M057393

Summaries for MIR298 Gene

Entrez Gene Summary for MIR298 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR298 Gene

MIR298 (MicroRNA 298) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR298 Gene

Genomics for MIR298 Gene

Products:

  1. Regulatory Element

Regulatory Elements for MIR298 Gene

Enhancers for MIR298 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR298 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR298 Gene

Chromosome:
20
Start:
58,818,226 bp from pter
End:
58,818,313 bp from pter
Size:
88 bases
Orientation:
Minus strand

Genomic View for MIR298 Gene

Genes around MIR298 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR298 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR298 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR298 Gene

ORGUL Member Location for MIR298 Gene

ORGUL Member Location for MIR298 gene

Proteins for MIR298 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR298 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR298 Gene

Domains & Families for MIR298 Gene

Gene Families for MIR298 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR298: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR298 Gene

Function for MIR298 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR298 Gene

Localization for MIR298 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR298 Gene

Pathways & Interactions for MIR298 Gene

SuperPathways for MIR298 Gene

PathCards logoMore details on SuperPathways for MIR298
No Data Available

Interacting Proteins for MIR298 Gene

Gene Ontology (GO) - Biological Process for MIR298 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR298 Gene

Drugs & Compounds for MIR298 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR298 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MIR298 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR298 Gene

No ASD Table

Relevant External Links for MIR298 Gene

GeneLoc Exon Structure for
MIR298
ECgene alternative splicing isoforms for
MIR298

Expression for MIR298 Gene

Products:

  1. Primer

mRNA expression in normal human tissues for MIR298 Gene

mRNA expression in normal human tissues for MIR298 Gene
mRNA expression by GTEx for MIR298 Gene
genes like me logo Genes that share expression patterns with MIR298: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR298 Gene

Orthologs for MIR298 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for MIR298 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
 Mammalia Mir298 36
  • 72 (a)
 OneToOne
chimpanzee
(Pan troglodytes)
 Mammalia ptr-mir-298 36
  • 100 (a)
 OneToOne
Species with no ortholog for MIR298:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR298 Gene

ENSEMBL:
Gene Tree for MIR298 (if available)
TreeFam:
Gene Tree for MIR298 (if available)

Paralogs for MIR298 Gene

No data available for Paralogs for MIR298 Gene

Variants for MIR298 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR298 Gene

Variant ID Type Subtype PubMed ID
nsv912963 CNV Gain 21882294
nsv912964 CNV Loss 21882294

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR298 Gene

Disorders for MIR298 Gene

Relevant External Links for MIR298

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR298

No disorders were found for MIR298 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR298 Gene

Publications for MIR298 Gene

  1. Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298. (PMID: 22521303) Bao L. … Dash S. (Am. J. Pathol. 2012) 3 67
  2. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR298 Gene

Sources for MIR298 Gene

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