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Aliases for MIR2861 Gene

Subcategory (RNA class) for MIR2861 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR2861 Gene

  • MicroRNA 2861 2 3 5
  • Hsa-Mir-2861 3
  • MIRN2861 3
  • BMND15 3

External Ids for MIR2861 Gene

Previous GeneCards Identifiers for MIR2861 Gene

  • GC09U901547
  • GC09P130548

Summaries for MIR2861 Gene

Entrez Gene Summary for MIR2861 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of target mRNAs. This microRNA may play a role in osteoblast differentiation and a mutation in this gene is associated with osteoporosis. Altered expression of this microRNA has been observed in human cancers, with reduced expression seen in cervical cancer, while expression in papillary thyroid carcinoma (PTC) is increased. [provided by RefSeq, Mar 2017]

GeneCards Summary for MIR2861 Gene

MIR2861 (MicroRNA 2861) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR2861 include Toxocariasis. Among its related pathways are HIV Life Cycle and Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2861 Gene

Genomics for MIR2861 Gene

Regulatory Elements for MIR2861 Gene


Promoters for MIR2861 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000337888 82 2401 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for MIR2861 Gene

Chromosome:
9
Start:
127,785,918 bp from pter
End:
127,786,007 bp from pter
Size:
90 bases
Orientation:
Plus strand

Genomic View for MIR2861 Gene

Genes around MIR2861 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2861 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2861 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2861 Gene

Proteins for MIR2861 Gene

Post-translational modifications for MIR2861 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2861 Gene

Domains & Families for MIR2861 Gene

Gene Families for MIR2861 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2861: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2861 Gene

Function for MIR2861 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2861 Gene

Localization for MIR2861 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2861 Gene

Pathways & Interactions for MIR2861 Gene

genes like me logo Genes that share pathways with MIR2861: view

Interacting Proteins for MIR2861 Gene

Gene Ontology (GO) - Biological Process for MIR2861 Gene

None

No data available for SIGNOR curated interactions for MIR2861 Gene

Drugs & Compounds for MIR2861 Gene

No Compound Related Data Available

Transcripts for MIR2861 Gene

mRNA/cDNA for MIR2861 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2861 Gene

No ASD Table

Relevant External Links for MIR2861 Gene

GeneLoc Exon Structure for
MIR2861
ECgene alternative splicing isoforms for
MIR2861

Expression for MIR2861 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2861 Gene:

MIR2861
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR2861 Gene

Orthologs for MIR2861 Gene

Evolution for MIR2861 Gene

ENSEMBL:
Gene Tree for MIR2861 (if available)
TreeFam:
Gene Tree for MIR2861 (if available)

No data available for Orthologs for MIR2861 Gene

Paralogs for MIR2861 Gene

No data available for Paralogs for MIR2861 Gene

Variants for MIR2861 Gene

Sequence variations from dbSNP and Humsavar for MIR2861 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs794728003 other 127,785,950(+) GGCCT(C/G)TCGGG nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB
rs1000622607 -- 127,784,616(+) GGAGG(G/T)GGAAT intron-variant, upstream-variant-2KB
rs1000911478 -- 127,784,670(+) CGCGA(G/T)GGGGG intron-variant, upstream-variant-2KB
rs1000925389 -- 127,784,697(+) TGAAC(C/G)GTGAG intron-variant, upstream-variant-2KB
rs1002805270 -- 127,785,314(+) GTGGG(A/G)GTAAA downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2861 Gene

Variant ID Type Subtype PubMed ID
dgv12879n54 CNV loss 21841781
esv3891727 CNV gain 25118596
nsv1075676 CNV deletion 25765185
nsv466573 CNV loss 19166990
nsv466575 CNV loss 19166990
nsv471323 CNV loss 18288195
nsv615371 CNV loss 21841781
nsv615373 CNV loss 21841781
nsv615374 CNV loss 21841781
nsv825094 CNV gain 20364138

Relevant External Links for MIR2861 Gene

Human Gene Mutation Database (HGMD)
MIR2861
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2861

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2861 Gene

Disorders for MIR2861 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR2861 Gene - From: GeneCards

Disorder Aliases PubMed IDs
toxocariasis
  • infection by toxascaris
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR2861

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR2861
genes like me logo Genes that share disorders with MIR2861: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR2861 Gene

Publications for MIR2861 Gene

  1. miR-2861 is involved in osteogenic commitment of human periodontal ligament stem cells grown onto 3D scaffold. (PMID: 28078846) Diomede F. … Trubiani O. (J. Biol. Regul. Homeost. Agents 2016) 3 64
  2. Serum miRNAs panel (miR-16-2*, miR-195, miR-2861, miR-497) as novel non-invasive biomarkers for detection of cervical cancer. (PMID: 26656154) Zhang Y. … Cui W. (Sci Rep 2015) 3 64
  3. Upregulation of miR-2861 and miR-451 expression in papillary thyroid carcinoma with lymph node metastasis. (PMID: 23609190) Wang Z. … Teng W. (Med. Oncol. 2013) 3 64
  4. A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans. (PMID: 19920351) Li H. … Luo X.H. (J. Clin. Invest. 2009) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR2861 Gene

Sources for MIR2861 Gene

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