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Aliases for MIR26B Gene

Subcategory (RNA class) for MIR26B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR26B Gene

  • MicroRNA 26b 2 3
  • MIRN26B 3 6
  • Hsa-Mir-26b 3
  • MiR-26b 3

External Ids for MIR26B Gene

ORGUL Members for MIR26B Gene

Previous Symbols for MIR26B Gene

  • MIRN26B

Summaries for MIR26B Gene

Entrez Gene Summary for MIR26B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR26B Gene

MIR26B (MicroRNA 26b) is a RNA Gene, and belongs to miRNA RNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR26B Gene

Genomics for MIR26B Gene

Genomic Location for MIR26B Gene

Start:
218,402,637 bp from pter
End:
218,402,746 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR26B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR26B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR26B Gene

No data available for Regulatory Elements for MIR26B Gene

Proteins for MIR26B Gene

Post-translational modifications for MIR26B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR26B Gene

Domains for MIR26B Gene

Gene Families for MIR26B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR26B: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR26B Gene

Function for MIR26B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR26B Gene

Localization for MIR26B Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR26B Gene

Pathways for MIR26B Gene

SuperPathways for MIR26B Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR26B: view

Pathways by source for MIR26B Gene

1 KEGG pathway for MIR26B Gene

Interacting Proteins for MIR26B Gene

Gene Ontology (GO) - Biological Process for MIR26B Gene

None

Transcripts for MIR26B Gene

mRNA/cDNA for MIR26B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR26B Gene

No ASD Table

Relevant External Links for MIR26B Gene

GeneLoc Exon Structure for
MIR26B
ECgene alternative splicing isoforms for
MIR26B

Expression for MIR26B Gene

mRNA expression in normal human tissues for MIR26B Gene

genes like me logo Genes that share expressions with MIR26B: view

Orthologs for MIR26B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR26B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-26b 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-26b 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-26b 37
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir26b 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-26-2 37
  • 84 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-26-1 37
  • 67 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-26-1 37
  • 65 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii dre-mir-26b 37
  • 52 (a)
OneToOne
Species with no ortholog for MIR26B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR26B Gene

ENSEMBL:
Gene Tree for MIR26B (if available)
TreeFam:
Gene Tree for MIR26B (if available)

Paralogs for MIR26B Gene

No data available for Paralogs for MIR26B Gene

Variants for MIR26B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR26B Gene

Variant ID Type Subtype PubMed ID
nsv519829 CNV Loss 19592680
nsv3166 CNV Insertion 18451855
dgv4435n71 CNV Loss 21882294
nsv875858 CNV Loss 21882294
nsv875860 CNV Loss 21882294

Relevant External Links for MIR26B Gene

HapMap Linkage Disequilibrium report
MIR26B

No data available for Sequence variations from dbSNP and Humsavar for MIR26B Gene

Disorders for MIR26B Gene

Relevant External Links for MIR26B

Genetic Association Database (GAD)
MIR26B
Human Genome Epidemiology (HuGE) Navigator
MIR26B
genes like me logo Genes that share disorders with MIR26B: view

No data available for UniProtKB/Swiss-Prot for MIR26B Gene

Publications for MIR26B Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 49
  2. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y. … Liu P. (Schizophr. Res. 2010) 3 49
  3. Human embryonic stem cells and metastatic colorectal cancer cells shared the common endogenous human microRNA-26b. (PMID: 20831567) Ma Y.L. … Qin H.L. (J. Cell. Mol. Med. 2011) 3
  4. Genetic polymorphisms in the precursor MicroRNA flanking region and non-small cell lung cancer survival. (PMID: 20889907) Hu Z. … Shen H. (Am. J. Respir. Crit. Care Med. 2011) 3
  5. Role of microRNA-26b in glioma development and its mediated regulation on EphA2. (PMID: 21264258) Wu N. … Lin X. (PLoS ONE 2011) 3

Products for MIR26B Gene

Sources for MIR26B Gene

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