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Aliases for MIR26B Gene

Subcategory (RNA class) for MIR26B Gene


Quality Score for this RNA gene is


Aliases for MIR26B Gene

  • MicroRNA 26b 2 3
  • Hsa-Mir-26b 3
  • MiR-26b 3
  • MIRN26B 3

External Ids for MIR26B Gene

ORGUL Members for MIR26B Gene

Previous HGNC Symbols for MIR26B Gene

  • MIRN26B

Previous GeneCards Identifiers for MIR26B Gene

  • GC02P218976
  • GC02P219267

Summaries for MIR26B Gene

Entrez Gene Summary for MIR26B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR26B Gene

MIR26B (MicroRNA 26b) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR26B Gene

Genomics for MIR26B Gene

Genomic Location for MIR26B Gene

218,402,637 bp from pter
218,402,746 bp from pter
110 bases
Plus strand

Genomic View for MIR26B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR26B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR26B Gene

No data available for Regulatory Elements for MIR26B Gene

Proteins for MIR26B Gene

Post-translational modifications for MIR26B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR26B Gene

Domains & Families for MIR26B Gene

Gene Families for MIR26B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR26B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR26B Gene

Function for MIR26B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR26B Gene

Localization for MIR26B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR26B Gene

Pathways & Interactions for MIR26B Gene

SuperPathways for MIR26B Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR26B: view

Pathways by source for MIR26B Gene

1 KEGG pathway for MIR26B Gene

Interacting Proteins for MIR26B Gene

Gene Ontology (GO) - Biological Process for MIR26B Gene


No data available for SIGNOR curated interactions for MIR26B Gene

Drugs & Compounds for MIR26B Gene

No Compound Related Data Available

Transcripts for MIR26B Gene

mRNA/cDNA for MIR26B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR26B Gene

No ASD Table

Relevant External Links for MIR26B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR26B Gene

mRNA expression in normal human tissues for MIR26B Gene

genes like me logo Genes that share expression patterns with MIR26B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR26B Gene

Orthologs for MIR26B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR26B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-26b 36
  • 89 (a)
(Canis familiaris)
Mammalia cfa-mir-26b 36
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-mir-26-2 36
  • 84 (a)
(Mus musculus)
Mammalia Mir26b 36
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-26-1 36
  • 67 (a)
(Pan troglodytes)
Mammalia ptr-mir-26b 36
  • 100 (a)
(Anolis carolinensis)
Reptilia aca-mir-26-1 36
  • 65 (a)
(Danio rerio)
Actinopterygii dre-mir-26b 36
  • 52 (a)
Species with no ortholog for MIR26B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR26B Gene

Gene Tree for MIR26B (if available)
Gene Tree for MIR26B (if available)

Paralogs for MIR26B Gene

No data available for Paralogs for MIR26B Gene

Variants for MIR26B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR26B Gene

Variant ID Type Subtype PubMed ID
nsv519829 CNV Loss 19592680
nsv3166 CNV Insertion 18451855
dgv4435n71 CNV Loss 21882294
nsv875858 CNV Loss 21882294
nsv875860 CNV Loss 21882294

Relevant External Links for MIR26B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR26B Gene

Disorders for MIR26B Gene

Relevant External Links for MIR26B

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR26B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR26B Gene

Publications for MIR26B Gene

  1. miR-26b is downregulated in human tongue squamous cell carcinoma and regulates cell proliferation and metastasis through a COX-2-dependent mechanism. (PMID: 25483152) Cao J. … Li Y. (Oncol. Rep. 2015) 67
  2. MicroRNA expression signature of oral squamous cell carcinoma: functional role of microRNA-26a/b in the modulation of novel cancer pathways. (PMID: 25668004) Fukumoto I. … Seki N. (Br. J. Cancer 2015) 67
  3. Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-I_B and angiogenesis in breast cancer cells. (PMID: 25536365) Anbalagan D. … Lim L.H. (PLoS ONE 2014) 67
  4. An emerging role for the miR-26 family in cardiovascular disease. (PMID: 25066487) Icli B. … Feinberg M.W. (Trends Cardiovasc. Med. 2014) 67
  5. MicroRNA-26b inhibits epithelial-mesenchymal transition in hepatocellular carcinoma by targeting USP9X. (PMID: 24890815) Shen G. … Jia H. (BMC Cancer 2014) 67

Products for MIR26B Gene

Sources for MIR26B Gene

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