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Aliases for MIR26A1 Gene

Subcategory (RNA class) for MIR26A1 Gene


Quality Score for this RNA gene is


Aliases for MIR26A1 Gene

  • MicroRNA 26a-1 2 3 5
  • Hsa-Mir-26a-1 3
  • Mir-26a-1 3
  • MIRN26A1 3
  • MIR26A 3

External Ids for MIR26A1 Gene

ORGUL Members for MIR26A1 Gene

Previous HGNC Symbols for MIR26A1 Gene

  • MIRN26A1

Previous GeneCards Identifiers for MIR26A1 Gene

  • GC03P037988
  • GC03P038010

Summaries for MIR26A1 Gene

Entrez Gene Summary for MIR26A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR26A1 Gene

MIR26A1 (MicroRNA 26a-1) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are miRs in Muscle Cell Differentiation and MicroRNAs in cancer.

Additional gene information for MIR26A1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR26A1 Gene

Genomics for MIR26A1 Gene

GeneHancer (GH) Regulatory Elements for MIR26A1 Gene

Promoters and enhancers for MIR26A1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I037968 Enhancer 0.6 ENCODE dbSUPER 550.8 0.0 -32 2.7 MITF USF2 MIR26A1 ITGA9-AS1 CTDSPL VILL GC03P037965
GH03I037903 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.6 -63.5 -63514 5 PKNOX1 FOXA2 ARID4B IRF4 ATF7 RUNX3 SP5 JUNB PPARG KAT8 CTDSPL ITGA9-AS1 MIR26A1 SLC22A14 GC03P037965
GH03I037941 Enhancer 1.2 Ensembl ENCODE dbSUPER 11.8 -24.8 -24807 5.7 HDAC1 PKNOX1 NFIB NEUROD1 BATF ATF7 FOS RCOR1 ZNF217 SP1 CTDSPL ITGA9-AS1 MIR26A1 VILL GC03P037965
GH03I037909 Enhancer 1.2 Ensembl ENCODE dbSUPER 11.6 -59.9 -59903 0.6 ELF3 FOXA2 MLX ZFP64 ARID4B DNMT3B THRB ZNF48 RARA CREM CTDSPL ITGA9-AS1 MIR26A1 GC03P037965
GH03I037967 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.8 -2.0 -2003 0.4 CTCF SAP130 TEAD4 ARID4B SIN3A RAD21 RARA TEAD3 CTBP1 ZNF143 GC03P037965 VILL CTDSPL ITGA9-AS1 MIR26A1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR26A1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR26A1 Gene

Genomic Locations for MIR26A1 Gene
77 bases
Plus strand

Genomic View for MIR26A1 Gene

Genes around MIR26A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR26A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR26A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR26A1 Gene

Proteins for MIR26A1 Gene

Post-translational modifications for MIR26A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR26A1 Gene

Domains & Families for MIR26A1 Gene

Gene Families for MIR26A1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR26A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR26A1 Gene

Function for MIR26A1 Gene

Gene Ontology (GO) - Molecular Function for MIR26A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 20660482
genes like me logo Genes that share ontologies with MIR26A1: view

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR26A1 Gene

Localization for MIR26A1 Gene

Gene Ontology (GO) - Cellular Components for MIR26A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 25203061
genes like me logo Genes that share ontologies with MIR26A1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR26A1 Gene

Pathways & Interactions for MIR26A1 Gene

genes like me logo Genes that share pathways with MIR26A1: view

Pathways by source for MIR26A1 Gene

2 BioSystems pathways for MIR26A1 Gene
1 KEGG pathway for MIR26A1 Gene

Interacting Proteins for MIR26A1 Gene

Gene Ontology (GO) - Biological Process for MIR26A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010459 negative regulation of heart rate ISS --
GO:0035195 gene silencing by miRNA IDA 20660482
GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization ISS --
GO:1903609 negative regulation of inward rectifier potassium channel activity ISS --
genes like me logo Genes that share ontologies with MIR26A1: view

No data available for SIGNOR curated interactions for MIR26A1 Gene

Drugs & Compounds for MIR26A1 Gene

No Compound Related Data Available

Transcripts for MIR26A1 Gene

mRNA/cDNA for MIR26A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR26A1 Gene

No ASD Table

Relevant External Links for MIR26A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR26A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR26A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR26A1 Gene:

genes like me logo Genes that share expression patterns with MIR26A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR26A1 Gene

Orthologs for MIR26A1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR26A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-26a-1 34
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-26a-1 34
  • 94 (a)
(Mus musculus)
Mammalia Mir26a-1 34
  • 84 (a)
(Bos Taurus)
Mammalia bta-mir-26a-1 34
  • 78 (a)
(Monodelphis domestica)
Mammalia mdo-mir-26-3 34
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-26-2 34
  • 62 (a)
(Gallus gallus)
Aves gga-mir-26a 34
  • 81 (a)
(Anolis carolinensis)
Reptilia aca-mir-26-2 34
  • 50 (a)
(Danio rerio)
Actinopterygii dre-mir-26a-3 34
  • 42 (a)
Species where no ortholog for MIR26A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR26A1 Gene

Gene Tree for MIR26A1 (if available)
Gene Tree for MIR26A1 (if available)

Paralogs for MIR26A1 Gene

No data available for Paralogs for MIR26A1 Gene

Variants for MIR26A1 Gene

Sequence variations from dbSNP and Humsavar for MIR26A1 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1001868746 -- 37,967,762(+) G/C upstream_transcript_variant
rs1003133832 -- 37,969,113(+) G/C upstream_transcript_variant
rs1003533569 -- 37,969,347(+) C/T upstream_transcript_variant
rs1008332438 -- 37,968,704(+) A/G upstream_transcript_variant
rs1010102099 -- 37,967,439(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR26A1 Gene

Variant ID Type Subtype PubMed ID
esv2759140 CNV loss 17122850
nsv428416 CNV loss 18775914
nsv522017 CNV loss 19592680
nsv590094 CNV loss 21841781

Additional Variant Information for MIR26A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR26A1 Gene

Disorders for MIR26A1 Gene

Additional Disease Information for MIR26A1

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR26A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR26A1 Gene

Publications for MIR26A1 Gene

  1. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J … Wu X (Molecular carcinogenesis 2010) 3 44 58
  2. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. (PMID: 20732906) Lin J … Wu X (Carcinogenesis 2010) 3 44 58
  3. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PMID: 19138993) Ye Y … Wu X (Cancer prevention research (Philadelphia, Pa.) 2008) 3 44 58
  4. MiR-26a Mediates Ultraviolet B-Induced Apoptosis by Targeting Histone Methyltransferase EZH2 Depending on Myc Expression. (PMID: 28977801) Zhang T … Li W (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017) 3 58
  5. TET-Mediated Sequestration of miR-26 Drives EZH2 Expression and Gastric Carcinogenesis. (PMID: 28923852) Deng M … He Z (Cancer research 2017) 3 58

Products for MIR26A1 Gene

Sources for MIR26A1 Gene

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