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Aliases for MIR26A1 Gene

Subcategory (RNA class) for MIR26A1 Gene

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Quality Score for this RNA gene is

3

Aliases for MIR26A1 Gene

  • MicroRNA 26a-1 2 3
  • MIRN26A1 3 6
  • MIR26A 3 6
  • Hsa-Mir-26a-1 3

External Ids for MIR26A1 Gene

ORGUL Members for MIR26A1 Gene

Previous HGNC Symbols for MIR26A1 Gene

  • MIRN26A1

Previous GeneCards Identifiers for MIR26A1 Gene

  • GC03P037988
  • GC03P038010

Summaries for MIR26A1 Gene

Entrez Gene Summary for MIR26A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR26A1 Gene

MIR26A1 (MicroRNA 26a-1) is an RNA Gene, and is affiliated with the undefined RNA class. Diseases associated with MIR26A1 include esophageal cancer. Among its related pathways are MicroRNAs in cancer and miRs in Muscle Cell Differentiation.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR26A1 Gene

Genomics for MIR26A1 Gene

Genomic Location for MIR26A1 Gene

Start:
37,969,404 bp from pter
End:
37,969,480 bp from pter
Size:
77 bases
Orientation:
Plus strand

Genomic View for MIR26A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR26A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR26A1 Gene

No data available for Regulatory Elements for MIR26A1 Gene

Proteins for MIR26A1 Gene

Post-translational modifications for MIR26A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR26A1 Gene

Domains for MIR26A1 Gene

Gene Families for MIR26A1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR26A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR26A1 Gene

Function for MIR26A1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR26A1 Gene

Localization for MIR26A1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR26A1 Gene

Pathways for MIR26A1 Gene

genes like me logo Genes that share pathways with MIR26A1: view

Pathways by source for MIR26A1 Gene

1 BioSystems pathway for MIR26A1 Gene
1 KEGG pathway for MIR26A1 Gene

Interacting Proteins for MIR26A1 Gene

Gene Ontology (GO) - Biological Process for MIR26A1 Gene

None

Transcripts for MIR26A1 Gene

mRNA/cDNA for MIR26A1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR26A1 Gene

No ASD Table

Relevant External Links for MIR26A1 Gene

GeneLoc Exon Structure for
MIR26A1
ECgene alternative splicing isoforms for
MIR26A1

Expression for MIR26A1 Gene

mRNA expression in normal human tissues for MIR26A1 Gene

genes like me logo Genes that share expressions with MIR26A1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR26A1 Gene

Orthologs for MIR26A1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR26A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-26a-1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-26a-1 36
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-26a-1 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir26a-1 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-26-3 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-26-2 36
  • 62 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-26a 36
  • 81 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-26-2 36
  • 50 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-26a-3 36
  • 42 (a)
OneToOne
Species with no ortholog for MIR26A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR26A1 Gene

ENSEMBL:
Gene Tree for MIR26A1 (if available)
TreeFam:
Gene Tree for MIR26A1 (if available)

Paralogs for MIR26A1 Gene

No data available for Paralogs for MIR26A1 Gene

Variants for MIR26A1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR26A1 Gene

Variant ID Type Subtype PubMed ID
dgv1447e1 CNV Complex 17122850
dgv1448e1 CNV Complex 17122850
nsv428416 CNV Loss 18775914
nsv522017 CNV Loss 19592680

Relevant External Links for MIR26A1 Gene

HapMap Linkage Disequilibrium report
MIR26A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR26A1 Gene

Disorders for MIR26A1 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR26A1 Gene including...

Search for MIR26A1 Gene in MalaCards »

Relevant External Links for MIR26A1

Genetic Association Database (GAD)
MIR26A1
Human Genome Epidemiology (HuGE) Navigator
MIR26A1
genes like me logo Genes that share disorders with MIR26A1: view

No data available for UniProtKB/Swiss-Prot for MIR26A1 Gene

Publications for MIR26A1 Gene

  1. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. (PMID: 20732906) Lin J. … Wu X. (Carcinogenesis 2010) 3 48
  2. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J. … Wu X. (Mol. Carcinog. 2010) 3 48
  3. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PMID: 19138993) Ye Y. … Wu X. (Cancer Prev Res (Phila) 2008) 3 48
  4. Zcchc11-dependent uridylation of microRNA directs cytokine expression. (PMID: 19701194) Jones M.R. … Mizgerd J.P. (Nat. Cell Biol. 2009) 3
  5. MicroRNA expression, survival, and response to interferon in liver cancer. (PMID: 19812400) Ji J. … Wang X.W. (N. Engl. J. Med. 2009) 3

Products for MIR26A1 Gene

Sources for MIR26A1 Gene

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