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Aliases for MIR26A1 Gene

Subcategory (RNA class) for MIR26A1 Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR26A1 Gene

  • MicroRNA 26a-1 2 3 5
  • Hsa-Mir-26a-1 3
  • Mir-26a-1 3
  • MIRN26A1 3
  • MIR26A 3

External Ids for MIR26A1 Gene

ORGUL Members for MIR26A1 Gene

Previous HGNC Symbols for MIR26A1 Gene

  • MIRN26A1

Previous GeneCards Identifiers for MIR26A1 Gene

  • GC03P037988
  • GC03P038010

Summaries for MIR26A1 Gene

Entrez Gene Summary for MIR26A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR26A1 Gene

MIR26A1 (MicroRNA 26a-1) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are miRs in Muscle Cell Differentiation and Parkinsons Disease Pathway.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR26A1 Gene

Genomics for MIR26A1 Gene

Regulatory Elements for MIR26A1 Gene

Enhancers for MIR26A1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G037903 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11.6 -63.5 -63515 5.0 PKNOX1 ARID4B GATA2 FOS SP5 JUNB PPARG TBX21 KAT8 SSRP1 CTDSPL ITGA9-AS1 MIR26A1 SLC22A14 GC03P037965
GH03G037941 1.6 Ensembl ENCODE dbSUPER 11.8 -24.8 -24807 5.7 HDGF FOXA2 PKNOX1 CREB3L1 MLX ARNT ARID4B YY1 ZNF766 FOS CTDSPL ITGA9-AS1 MIR26A1 C3orf35 VILL GC03P037965
GH03G037909 1.4 Ensembl ENCODE dbSUPER 11.6 -59.9 -59903 0.6 ELF3 FOXA2 MLX ZFP64 ARID4B DNMT3B THRB ZNF48 RARA GATA4 CTDSPL ITGA9-AS1 MIR26A1 GC03P037965
GH03G037967 1.2 Ensembl ENCODE dbSUPER 0.7 -2.0 -2003 0.4 CTCF SAP130 WRNIP1 TEAD4 ARID4B RAD21 RARA TEAD3 POLR2A SMC3 VILL CTDSPL ITGA9-AS1 GC03P037965 MIR26A1
GH03G037968 0.8 ENCODE dbSUPER 0.7 0.0 -32 2.7 RAD51 SMARCA4 POLR2A AGO1 USF2 ZBTB33 RBFOX2 CTDSPL ITGA9-AS1 VILL MIR26A1 GC03P037965
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR26A1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR26A1 Gene

Chromosome:
3
Start:
37,969,404 bp from pter
End:
37,969,480 bp from pter
Size:
77 bases
Orientation:
Plus strand

Genomic View for MIR26A1 Gene

Genes around MIR26A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR26A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR26A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR26A1 Gene

Proteins for MIR26A1 Gene

Post-translational modifications for MIR26A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR26A1 Gene

Domains & Families for MIR26A1 Gene

Gene Families for MIR26A1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR26A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR26A1 Gene

Function for MIR26A1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR26A1 Gene

Localization for MIR26A1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR26A1 Gene

Pathways & Interactions for MIR26A1 Gene

genes like me logo Genes that share pathways with MIR26A1: view

Pathways by source for MIR26A1 Gene

2 BioSystems pathways for MIR26A1 Gene
1 KEGG pathway for MIR26A1 Gene

Interacting Proteins for MIR26A1 Gene

Gene Ontology (GO) - Biological Process for MIR26A1 Gene

None

No data available for SIGNOR curated interactions for MIR26A1 Gene

Drugs & Compounds for MIR26A1 Gene

No Compound Related Data Available

Transcripts for MIR26A1 Gene

mRNA/cDNA for MIR26A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR26A1 Gene

No ASD Table

Relevant External Links for MIR26A1 Gene

GeneLoc Exon Structure for
MIR26A1
ECgene alternative splicing isoforms for
MIR26A1

Expression for MIR26A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR26A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR26A1 Gene:

MIR26A1
genes like me logo Genes that share expression patterns with MIR26A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR26A1 Gene

Orthologs for MIR26A1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR26A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-26a-1 35
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-26a-1 35
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir26a-1 35
  • 84 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-26a-1 35
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-26-3 35
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-26-2 35
  • 62 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-26a 35
  • 81 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-26-2 35
  • 50 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-26a-3 35
  • 42 (a)
OneToOne
Species where no ortholog for MIR26A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR26A1 Gene

ENSEMBL:
Gene Tree for MIR26A1 (if available)
TreeFam:
Gene Tree for MIR26A1 (if available)

Paralogs for MIR26A1 Gene

No data available for Paralogs for MIR26A1 Gene

Variants for MIR26A1 Gene

Sequence variations from dbSNP and Humsavar for MIR26A1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1001868746 -- 37,967,762(+) TTCTT(C/G)CTAAA intron-variant, upstream-variant-2KB
rs1003133832 -- 37,969,113(+) TTAAG(C/G)CTTCT intron-variant, upstream-variant-2KB
rs1003533569 -- 37,969,347(+) TCTCC(C/T)GAGGG intron-variant, upstream-variant-2KB
rs1008332438 -- 37,968,704(+) ATGTC(A/G)GTAGT intron-variant, upstream-variant-2KB
rs1010102099 -- 37,967,439(+) TCAAG(C/T)AGCAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR26A1 Gene

Variant ID Type Subtype PubMed ID
esv2759140 CNV loss 17122850
nsv428416 CNV loss 18775914
nsv522017 CNV loss 19592680
nsv590094 CNV loss 21841781

Relevant External Links for MIR26A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR26A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR26A1 Gene

Disorders for MIR26A1 Gene

Relevant External Links for MIR26A1

Genetic Association Database (GAD)
MIR26A1
Human Genome Epidemiology (HuGE) Navigator
MIR26A1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR26A1

No disorders were found for MIR26A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR26A1 Gene

Publications for MIR26A1 Gene

  1. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J. … Wu X. (Mol. Carcinog. 2010) 3 46 64
  2. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. (PMID: 20732906) Lin J. … Wu X. (Carcinogenesis 2010) 3 46 64
  3. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PMID: 19138993) Ye Y. … Wu X. (Cancer Prev Res (Phila) 2008) 3 46 64
  4. Regulation of metastasis-promoting LOXL2 gene expression by antitumor microRNAs in prostate cancer. (PMID: 27278788) Kato M. … Seki N. (J. Hum. Genet. 2017) 3 64
  5. Analysis of Circulating miR-1, miR-23a, and miR-26a in Atrial Fibrillation Patients Undergoing Coronary Bypass Artery Grafting Surgery. (PMID: 28422282) Feldman A. … Farsky P. (Ann. Hum. Genet. 2017) 3 64

Products for MIR26A1 Gene

Sources for MIR26A1 Gene

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