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Aliases for MIR2682 Gene

Subcategory (RNA class) for MIR2682 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR2682 Gene

  • MicroRNA 2682 2 3
  • MIR137 Host Gene 5
  • Hsa-Mir-2682 3
  • MIR137HG 5
  • Mir-2682 3

External Ids for MIR2682 Gene

Previous GeneCards Identifiers for MIR2682 Gene

  • GC01U903270
  • GC01M098512
  • GC01M098514

Summaries for MIR2682 Gene

Entrez Gene Summary for MIR2682 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2682 Gene

MIR2682 (MicroRNA 2682) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2682 Gene

Genomics for MIR2682 Gene

Regulatory Elements for MIR2682 Gene

Enhancers for MIR2682 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F097998 0.2 ENCODE 10.4 +50.3 50287 2.4 JUND JUN MAFK MIR137 MIR137HG MIR2682 GC01P098016 ENSG00000259946
GH01F098052 0.8 FANTOM5 Ensembl ENCODE 0.8 -4.1 -4070 2.9 CTCF JUN SIN3A RAD21 POLR2A EGR1 ZNF143 SMC3 FOS ZNF202 MIR137 MIR137HG MIR2682 NFU1P2
GH01F098047 0.4 FANTOM5 0.8 +2.4 2436 0.3 ENSG00000259946 GC01M098047 MIR137 MIR137HG MIR2682
GH01F098048 1.1 ENCODE 0.8 +1.4 1424 0.2 ELF3 ARID4B SIN3A ZNF48 ZSCAN9 RAD21 ZBTB40 RARA ZNF143 RCOR1 GC01M098047 MIR137 MIR137HG MIR2682
GH01F098051 0.6 ENCODE 0.8 -1.4 -1397 0.2 CTCF ZNF654 TEAD4 TRIM22 MIER2 RAD21 RFX5 TEAD3 SMARCA4 ZNF143 MIR137 MIR137HG MIR2682 NFU1P2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR2682 on UCSC Golden Path with GeneCards custom track

Promoters for MIR2682 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001522841 1163 1001 ELF3 SIN3A ZNF48 ZSCAN9 RAD21 ZBTB40 RARA ZNF143 RCOR1 ZNF202

Genomic Location for MIR2682 Gene

Chromosome:
1
Start:
97,986,740 bp from pter
End:
98,049,863 bp from pter
Size:
63,124 bases
Orientation:
Minus strand

Genomic View for MIR2682 Gene

Genes around MIR2682 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2682 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2682 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2682 Gene

Proteins for MIR2682 Gene

Post-translational modifications for MIR2682 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2682 Gene

Domains & Families for MIR2682 Gene

Gene Families for MIR2682 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2682: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2682 Gene

Function for MIR2682 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2682 Gene

Localization for MIR2682 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2682 Gene

Pathways & Interactions for MIR2682 Gene

SuperPathways for MIR2682 Gene

No Data Available

Interacting Proteins for MIR2682 Gene

Gene Ontology (GO) - Biological Process for MIR2682 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR2682 Gene

Transcripts for MIR2682 Gene

mRNA/cDNA for MIR2682 Gene

(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2682 Gene

No ASD Table

Relevant External Links for MIR2682 Gene

GeneLoc Exon Structure for
MIR2682
ECgene alternative splicing isoforms for
MIR2682

Expression for MIR2682 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR2682 Gene

mRNA expression in normal human tissues for MIR2682 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2682 Gene:

MIR2682
genes like me logo Genes that share expression patterns with MIR2682: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR2682 Gene

Orthologs for MIR2682 Gene

Evolution for MIR2682 Gene

ENSEMBL:
Gene Tree for MIR2682 (if available)
TreeFam:
Gene Tree for MIR2682 (if available)

No data available for Orthologs for MIR2682 Gene

Paralogs for MIR2682 Gene

No data available for Paralogs for MIR2682 Gene

Variants for MIR2682 Gene

Sequence variations from dbSNP and Humsavar for MIR2682 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111459339 -- 98,046,785(+) ATGGA(A/G)AATAA intron-variant, upstream-variant-2KB
rs112693582 -- 98,045,869(+) CCCCG(C/T)CCATC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs112984663 -- 98,045,861(+) CTTCC(A/G)CTCCC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs113227460 -- 98,046,887(+) AATGA(-/T)TTTTA intron-variant, upstream-variant-2KB
rs113401150 -- 98,045,848(+) GGAAA(C/T)GGACC intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2682 Gene

Variant ID Type Subtype PubMed ID
nsv470729 CNV loss 18288195
nsv546874 CNV loss 21841781
nsv819568 CNV gain 19587683
nsv830736 CNV gain 17160897

Relevant External Links for MIR2682 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2682

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2682 Gene

Disorders for MIR2682 Gene

Relevant External Links for MIR2682

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR2682

No disorders were found for MIR2682 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2682 Gene

Publications for MIR2682 Gene

  1. A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder. (PMID: 25434007) Duan J. … Gejman P.V. (Am. J. Hum. Genet. 2014) 3 64
  2. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3 64
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  4. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  5. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton C.J. … Gunaratne P.H. (PLoS ONE 2010) 3 64

Products for MIR2682 Gene

Sources for MIR2682 Gene

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