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Aliases for MIR2682 Gene

Subcategory (RNA class) for MIR2682 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR2682 Gene

  • MicroRNA 2682 2 3 5
  • Hsa-Mir-2682 3
  • Mir-2682 3

External Ids for MIR2682 Gene

Previous GeneCards Identifiers for MIR2682 Gene

  • GC01U903270
  • GC01M098512
  • GC01M098514

Summaries for MIR2682 Gene

Entrez Gene Summary for MIR2682 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2682 Gene

MIR2682 (MicroRNA 2682) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR2682 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR2682

Additional gene information for MIR2682 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR2682 Gene

Genomics for MIR2682 Gene

Regulatory Elements for MIR2682 Gene

Enhancers for MIR2682 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H098034 1 FANTOM5 Ensembl ENCODE 0.4 +10.8 10784 0 POLR2A DPYD MIR2682 GC01P098017
GH01H098044 0.5 ENCODE 0.7 0.0 -22 2 POLR2A RAD21 ZBTB20 EZH2 MIR137 MIR2682
GH01H098028 0.8 FANTOM5 Ensembl 0.4 +16.4 16407 0 JUND CEBPB EP300 MIR2682 GC01P098017
GH01H098030 0.5 ENCODE 0.4 +14.7 14672 0 PKNOX1 JUND POLR2A JUN MIR2682 GC01P098017
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR2682 on UCSC Golden Path with GeneCards custom track

Promoters for MIR2682 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000010436 -549 1001 POLR2A RAD21 ZBTB20 EZH2

Genomic Location for MIR2682 Gene

Chromosome:
1
Start:
98,045,242 bp from pter
End:
98,045,351 bp from pter
Size:
110 bases
Orientation:
Minus strand

Genomic View for MIR2682 Gene

Genes around MIR2682 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2682 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2682 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2682 Gene

ORGUL Member Location for MIR2682 Gene

ORGUL Member Location for MIR2682 gene

Proteins for MIR2682 Gene

Post-translational modifications for MIR2682 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2682 Gene

Domains & Families for MIR2682 Gene

Gene Families for MIR2682 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2682: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2682 Gene

Function for MIR2682 Gene

Phenotypes From GWAS Catalog for MIR2682 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR2682
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2682 Gene

Localization for MIR2682 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR2682 Gene

Pathways & Interactions for MIR2682 Gene

SuperPathways for MIR2682 Gene

No Data Available

Interacting Proteins for MIR2682 Gene

Gene Ontology (GO) - Biological Process for MIR2682 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR2682 Gene

Drugs & Compounds for MIR2682 Gene

No Compound Related Data Available

Transcripts for MIR2682 Gene

fRNAdb Secondary structures for MIR2682 Gene

  • FR509861

mRNA/cDNA for MIR2682 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR2682
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2682 Gene

No ASD Table

Relevant External Links for MIR2682 Gene

GeneLoc Exon Structure for
MIR2682
ECgene alternative splicing isoforms for
MIR2682

Expression for MIR2682 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR2682 Gene

mRNA expression in normal human tissues for MIR2682 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2682 Gene:

MIR2682
genes like me logo Genes that share expression patterns with MIR2682: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR2682 Gene

Orthologs for MIR2682 Gene

Evolution for MIR2682 Gene

ENSEMBL:
Gene Tree for MIR2682 (if available)
TreeFam:
Gene Tree for MIR2682 (if available)

No data available for Orthologs for MIR2682 Gene

Paralogs for MIR2682 Gene

No data available for Paralogs for MIR2682 Gene

Variants for MIR2682 Gene

Sequence variations from dbSNP and Humsavar for MIR2682 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000823142 -- 98,045,967(+) CAGTG(A/C)GAAAA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1001182415 -- 98,046,574(+) CTGGT(A/C)TCGGC nc-transcript-variant, upstream-variant-2KB
rs1001318285 -- 98,046,313(+) AATCC(A/G)TAACT nc-transcript-variant, upstream-variant-2KB
rs1001918108 -- 98,046,650(+) AGTTA(A/C)CCACA intron-variant, upstream-variant-2KB
rs1003916644 -- 98,045,697(+) GCCTC(A/C)CTCGC intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2682 Gene

Variant ID Type Subtype PubMed ID
nsv470729 CNV loss 18288195
nsv546874 CNV loss 21841781
nsv819568 CNV gain 19587683
nsv830736 CNV gain 17160897

Relevant External Links for MIR2682 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2682

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2682 Gene

Disorders for MIR2682 Gene

Relevant External Links for MIR2682

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR2682

No disorders were found for MIR2682 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2682 Gene

Publications for MIR2682 Gene

  1. A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder. (PMID: 25434007) Duan J … Gejman PV (American journal of human genetics 2014) 3 60
  2. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 60
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  4. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  5. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 60

Products for MIR2682 Gene

Sources for MIR2682 Gene

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