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Aliases for MIR25 Gene

Subcategory (RNA class) for MIR25 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR25 Gene

  • MicroRNA 25 2 3
  • MIRN25 3 6
  • Hsa-Mir-25 3
  • MiR-25 3

External Ids for MIR25 Gene

Previous Symbols for MIR25 Gene

  • MIRN25

Summaries for MIR25 Gene

Entrez Gene Summary for MIR25 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR25 Gene

MIR25 (MicroRNA 25) is a RNA Gene, and belongs to miRNA RNA class. Diseases associated with MIR25 include tongue squamous cell carcinoma. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR25 Gene

Genomics for MIR25 Gene

Genomic Location for MIR25 Gene

Start:
100,093,560 bp from pter
End:
100,093,643 bp from pter
Size:
84 bases
Orientation:
Minus strand

Genomic View for MIR25 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR25 Gene

No data available for Regulatory Elements for MIR25 Gene

Proteins for MIR25 Gene

Post-translational modifications for MIR25 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR25 Gene

Domains for MIR25 Gene

Gene Families for MIR25 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR25: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR25 Gene

Function for MIR25 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR25 Gene

Localization for MIR25 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR25 Gene

Pathways for MIR25 Gene

genes like me logo Genes that share pathways with MIR25: view

Pathways by source for MIR25 Gene

1 BioSystems pathway for MIR25 Gene
1 KEGG pathway for MIR25 Gene

Interacting Proteins for MIR25 Gene

Gene Ontology (GO) - Biological Process for MIR25 Gene

None

Transcripts for MIR25 Gene

mRNA/cDNA for MIR25 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR25 Gene

No ASD Table

Relevant External Links for MIR25 Gene

GeneLoc Exon Structure for
MIR25
ECgene alternative splicing isoforms for
MIR25

Expression for MIR25 Gene

mRNA expression in normal human tissues for MIR25 Gene

genes like me logo Genes that share expressions with MIR25: view

Orthologs for MIR25 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR25 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-25 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-25 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-25 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir25 37
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-25 37
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 86 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-25 37
  • 74 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-92b 37
  • 36 (a)
OneToOne
Species with no ortholog for MIR25:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR25 Gene

ENSEMBL:
Gene Tree for MIR25 (if available)
TreeFam:
Gene Tree for MIR25 (if available)

Paralogs for MIR25 Gene

No data available for Paralogs for MIR25 Gene

Variants for MIR25 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR25 Gene

Variant ID Type Subtype PubMed ID
nsv469687 CNV Loss 16826518
esv2734888 CNV Deletion 23290073
nsv510966 CNV Complex 20534489

Relevant External Links for MIR25 Gene

HapMap Linkage Disequilibrium report
MIR25

No data available for Sequence variations from dbSNP and Humsavar for MIR25 Gene

Disorders for MIR25 Gene

genes like me logo Genes that share disorders with MIR25: view

No data available for UniProtKB/Swiss-Prot for MIR25 Gene

Publications for MIR25 Gene

  1. Identification of novel genes coding for small expressed RNAs. (PMID: 11679670) Lagos-Quintana M. … Tuschl T. (Science 2001) 3
  2. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. (PMID: 15325244) Kasashima K. … Kozu T. (Biochem. Biophys. Res. Commun. 2004) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3

Products for MIR25 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR25
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR25
    • Block miRNA regulation of MIR25 using miScript Target Protectors

    Sources for MIR25 Gene

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