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Aliases for MIR24-2 Gene

Subcategory (RNA class) for MIR24-2 Gene

miRNA

Quality Score for this RNA gene is

14

Aliases for MIR24-2 Gene

  • MicroRNA 24-2 2 3 5
  • Hsa-Mir-24-2 3
  • MiRNA24-2 3
  • MiR-24-2 3
  • MIRN24-2 3

External Ids for MIR24-2 Gene

Previous HGNC Symbols for MIR24-2 Gene

  • MIRN24-2

Previous GeneCards Identifiers for MIR24-2 Gene

  • GC19M013845
  • GC19M013851
  • GC19M013947
  • GC19M013860
  • GC19M013865
  • GC19M013870
  • GC19M013876
  • GC19M013881
  • GC19M013893

Summaries for MIR24-2 Gene

Entrez Gene Summary for MIR24-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR24-2 Gene

MIR24-2 (MicroRNA 24-2) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR24-2 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

Additional gene information for MIR24-2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR24-2 Gene

Genomics for MIR24-2 Gene

Regulatory Elements for MIR24-2 Gene

Enhancers for MIR24-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H013793 1.3 ENCODE dbSUPER 12.6 +40.5 40512 5 HDGF PKNOX1 FOXA2 ARID4B SIN3A ZNF2 ZBTB7B YY1 ZNF143 ZNF207 LOC284454 DDX39A C19orf53 MRI1 MIR23A MIR24-2 MIR27A DCAF15 RFX1 FARSA
GH19H013787 1 Ensembl ENCODE 12.6 +47.3 47330 4 BCOR JUN ZMYM3 MAX CEBPG ZNF121 POLR2A ADNP RFX1 ZNF687 C19orf53 MIR23A MIR24-2 MIR27A MRI1 MISP3 GC19P013795
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR24-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR24-2 Gene

Chromosome:
19
Start:
13,836,287 bp from pter
End:
13,836,359 bp from pter
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR24-2 Gene

Genes around MIR24-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR24-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR24-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR24-2 Gene

ORGUL Member Location for MIR24-2 Gene

ORGUL Member Location for MIR24-2 gene

Proteins for MIR24-2 Gene

Post-translational modifications for MIR24-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR24-2 Gene

Domains & Families for MIR24-2 Gene

Gene Families for MIR24-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR24-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR24-2 Gene

Function for MIR24-2 Gene

Gene Ontology (GO) - Molecular Function for MIR24-2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IMP 23836801
genes like me logo Genes that share ontologies with MIR24-2: view

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR24-2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR24-2 Gene

Localization for MIR24-2 Gene

Gene Ontology (GO) - Cellular Components for MIR24-2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 18766170
GO:0070062 extracellular exosome IDA 28159509
genes like me logo Genes that share ontologies with MIR24-2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR24-2 Gene

Pathways & Interactions for MIR24-2 Gene

SuperPathways for MIR24-2 Gene

No Data Available

Interacting Proteins for MIR24-2 Gene

Gene Ontology (GO) - Biological Process for MIR24-2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010667 negative regulation of cardiac muscle cell apoptotic process ISS --
GO:0016525 negative regulation of angiogenesis IDA 23774796
GO:0035195 gene silencing by miRNA IMP 23774796
GO:0061049 cell growth involved in cardiac muscle cell development ISS --
GO:0070374 positive regulation of ERK1 and ERK2 cascade ISS --
genes like me logo Genes that share ontologies with MIR24-2: view

No data available for Pathways by source and SIGNOR curated interactions for MIR24-2 Gene

Drugs & Compounds for MIR24-2 Gene

No Compound Related Data Available

Transcripts for MIR24-2 Gene

mRNA/cDNA for MIR24-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR24-2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR24-2 Gene

No ASD Table

Relevant External Links for MIR24-2 Gene

GeneLoc Exon Structure for
MIR24-2
ECgene alternative splicing isoforms for
MIR24-2

Expression for MIR24-2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR24-2 Gene

This gene is overexpressed in Whole Blood (x4.8).

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR24-2 Gene

Orthologs for MIR24-2 Gene

Evolution for MIR24-2 Gene

ENSEMBL:
Gene Tree for MIR24-2 (if available)
TreeFam:
Gene Tree for MIR24-2 (if available)

No data available for Orthologs for MIR24-2 Gene

Paralogs for MIR24-2 Gene

No data available for Paralogs for MIR24-2 Gene

Variants for MIR24-2 Gene

Sequence variations from dbSNP and Humsavar for MIR24-2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000538048 -- 13,837,030(+) AAGTG(A/G)TCTCA upstream-variant-2KB
rs1001463246 -- 13,838,118(+) GCCAT(C/G)TTGCC upstream-variant-2KB
rs1001573587 -- 13,837,391(+) GTAAG(C/T)GCCCA upstream-variant-2KB
rs1001978328 -- 13,838,043(+) TCGGC(A/T)TTCCA upstream-variant-2KB
rs1003195008 -- 13,837,157(+) ATGCC(A/G)GCAGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR24-2 Gene

Variant ID Type Subtype PubMed ID
nsv833757 CNV loss 17160897
nsv953979 CNV deletion 24416366

Relevant External Links for MIR24-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR24-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR24-2 Gene

Disorders for MIR24-2 Gene

Relevant External Links for MIR24-2

Genetic Association Database (GAD)
MIR24-2
Human Genome Epidemiology (HuGE) Navigator
MIR24-2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR24-2

No disorders were found for MIR24-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR24-2 Gene

Publications for MIR24-2 Gene

  1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y … Liu P (Schizophrenia research 2010) 3 45 60
  2. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J … Zhao H (International journal of cancer 2009) 3 45 60
  3. Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis. (PMID: 28159509) Beltrami C … Emanueli C (Molecular therapy : the journal of the American Society of Gene Therapy 2017) 3 60
  4. Elevated expression of miR-24-3p is a potentially adverse prognostic factor in colorectal adenocarcinoma. (PMID: 27939727) Kerimis D … Scorilas A (Clinical biochemistry 2017) 3 60
  5. miR-24-3p Is Overexpressed in Hodgkin Lymphoma and Protects Hodgkin and Reed-Sternberg Cells from Apoptosis. (PMID: 28432871) Yuan Y … van den Berg A (The American journal of pathology 2017) 3 60

Products for MIR24-2 Gene

Sources for MIR24-2 Gene

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