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Aliases for MIR24-2 Gene

Subcategory (RNA class) for MIR24-2 Gene

lncRNA

Quality Score for this RNA gene is

8.2

Aliases for MIR24-2 Gene

  • MicroRNA 24-2 2 3 5
  • Hsa-Mir-24-2 3
  • MiRNA24-2 3
  • MiR-24-2 3
  • MIRN24-2 3

External Ids for MIR24-2 Gene

ORGUL Members for MIR24-2 Gene

Previous HGNC Symbols for MIR24-2 Gene

  • MIRN24-2

Previous GeneCards Identifiers for MIR24-2 Gene

  • GC19M013845
  • GC19M013851
  • GC19M013947
  • GC19M013860
  • GC19M013865
  • GC19M013870

Summaries for MIR24-2 Gene

Entrez Gene Summary for MIR24-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR24-2 Gene

MIR24-2 (MicroRNA 24-2) is an RNA Gene, and is affiliated with the lncRNA class.

fRNAdb sequence ontologies for MIR24-2 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR24-2

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR24-2 Gene

Genomics for MIR24-2 Gene

Regulatory Elements for MIR24-2 Gene

Enhancers for MIR24-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR24-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR24-2 Gene

Chromosome:
19
Start:
13,834,516 bp from pter
End:
13,836,359 bp from pter
Size:
1,844 bases
Orientation:
Minus strand

Genomic View for MIR24-2 Gene

Genes around MIR24-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR24-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR24-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR24-2 Gene

ORGUL Member Location for MIR24-2 Gene

ORGUL Member Location for MIR24-2 gene

Proteins for MIR24-2 Gene

Post-translational modifications for MIR24-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR24-2 Gene

Domains & Families for MIR24-2 Gene

Gene Families for MIR24-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR24-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR24-2 Gene

Function for MIR24-2 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR24-2 Gene

Localization for MIR24-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR24-2 Gene

Pathways & Interactions for MIR24-2 Gene

SuperPathways for MIR24-2 Gene

No Data Available

Interacting Proteins for MIR24-2 Gene

Gene Ontology (GO) - Biological Process for MIR24-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR24-2 Gene

Drugs & Compounds for MIR24-2 Gene

No Compound Related Data Available

Transcripts for MIR24-2 Gene

fRNAdb Secondary structures for MIR24-2 Gene

  • FR397352

mRNA/cDNA for MIR24-2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR24-2 Gene

No ASD Table

Relevant External Links for MIR24-2 Gene

GeneLoc Exon Structure for
MIR24-2
ECgene alternative splicing isoforms for
MIR24-2

Expression for MIR24-2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR24-2 Gene

This gene is overexpressed in Whole Blood (x4.8).

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR24-2 Gene

Orthologs for MIR24-2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR24-2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-24-2 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-24-2 35
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-24-2 35
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir24-2 35
  • 61 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-24-2 35
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-24-2 35
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-24 35
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-24-1 35
  • 83 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii BX664751.1 35
  • 54 (a)
OneToMany
dre-mir-24-1 35
  • 61 (a)
OneToMany
mir24-2 35
  • 62 (a)
OneToMany
mir24-2 35
  • 62 (a)
OneToMany
Species where no ortholog for MIR24-2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR24-2 Gene

ENSEMBL:
Gene Tree for MIR24-2 (if available)
TreeFam:
Gene Tree for MIR24-2 (if available)

Paralogs for MIR24-2 Gene

No data available for Paralogs for MIR24-2 Gene

Variants for MIR24-2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR24-2 Gene

Variant ID Type Subtype PubMed ID
nsv833757 CNV loss 17160897
nsv953979 CNV deletion 24416366

Relevant External Links for MIR24-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR24-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR24-2 Gene

Disorders for MIR24-2 Gene

Relevant External Links for MIR24-2

Genetic Association Database (GAD)
MIR24-2
Human Genome Epidemiology (HuGE) Navigator
MIR24-2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR24-2

No disorders were found for MIR24-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR24-2 Gene

Publications for MIR24-2 Gene

  1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y. … Liu P. (Schizophr. Res. 2010) 3 46 65
  2. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 46 65
  3. Mir-24-3p downregulation contributes to VP16-DDP resistance in small-cell lung cancer by targeting ATG4A. (PMID: 25426560) Pan B. … Chen L. (Oncotarget 2015) 3 65
  4. Down-regulation of miR-24-3p in colorectal cancer is associated with malignant behavior. (PMID: 25502080) Gao Y. … Wang C. (Med. Oncol. 2015) 3 65
  5. miR-24, miR-30b, and miR-142-3p regulate phagocytosis in myeloid inflammatory cells. (PMID: 25601927) Naqvi A.R. … Nares S. (J. Immunol. 2015) 3 65

Products for MIR24-2 Gene

Sources for MIR24-2 Gene

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