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Aliases for MIR24-2 Gene

Subcategory (RNA class) for MIR24-2 Gene

miRNA

Quality Score for this RNA gene is

14

Aliases for MIR24-2 Gene

  • MicroRNA 24-2 2 3
  • MIRN24-2 3 6
  • Hsa-Mir-24-2 3
  • MiRNA24-2 3
  • MiR-24-2 3

External Ids for MIR24-2 Gene

Previous HGNC Symbols for MIR24-2 Gene

  • MIRN24-2

Previous GeneCards Identifiers for MIR24-2 Gene

  • GC19M013845
  • GC19M013851
  • GC19M013947

Summaries for MIR24-2 Gene

Entrez Gene Summary for MIR24-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR24-2 Gene

MIR24-2 (MicroRNA 24-2) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR24-2 include familial breast cancer.

fRNAdb sequence ontologies for MIR24-2 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR24-2 Gene

Genomics for MIR24-2 Gene

Genomic Location for MIR24-2 Gene

Start:
13,836,287 bp from pter
End:
13,836,359 bp from pter
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR24-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR24-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR24-2 Gene

ORGUL Member Location for MIR24-2 Gene

ORGUL Member Location for MIR24-2 gene

No data available for Regulatory Elements for MIR24-2 Gene

Proteins for MIR24-2 Gene

Post-translational modifications for MIR24-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR24-2 Gene

Domains for MIR24-2 Gene

Gene Families for MIR24-2 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR24-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR24-2 Gene

Function for MIR24-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR24-2 Gene

Localization for MIR24-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR24-2 Gene

Pathways for MIR24-2 Gene

SuperPathways for MIR24-2 Gene

No Data Available

Interacting Proteins for MIR24-2 Gene

Gene Ontology (GO) - Biological Process for MIR24-2 Gene

None

No data available for Pathways by source for MIR24-2 Gene

Transcripts for MIR24-2 Gene

mRNA/cDNA for MIR24-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR24-2 Gene

No ASD Table

Relevant External Links for MIR24-2 Gene

GeneLoc Exon Structure for
MIR24-2
ECgene alternative splicing isoforms for
MIR24-2

Expression for MIR24-2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR24-2 Gene

This gene is overexpressed in Whole Blood (4.8).

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for MIR24-2 Gene

Orthologs for MIR24-2 Gene

Evolution for MIR24-2 Gene

ENSEMBL:
Gene Tree for MIR24-2 (if available)
TreeFam:
Gene Tree for MIR24-2 (if available)

No data available for Orthologs for MIR24-2 Gene

Paralogs for MIR24-2 Gene

No data available for Paralogs for MIR24-2 Gene

Variants for MIR24-2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR24-2 Gene

Variant ID Type Subtype PubMed ID
nsv833757 CNV Loss 17160897
nsv911097 CNV Loss 21882294
nsv911098 CNV Loss 21882294
dgv3738n71 CNV Loss 21882294

Relevant External Links for MIR24-2 Gene

HapMap Linkage Disequilibrium report
MIR24-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR24-2 Gene

Disorders for MIR24-2 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR24-2 Gene including...

Search for MIR24-2 Gene in MalaCards »

Relevant External Links for MIR24-2

Genetic Association Database (GAD)
MIR24-2
Human Genome Epidemiology (HuGE) Navigator
MIR24-2
genes like me logo Genes that share disorders with MIR24-2: view

No data available for UniProtKB/Swiss-Prot for MIR24-2 Gene

Publications for MIR24-2 Gene

  1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y. … Liu P. (Schizophr. Res. 2010) 3 48
  2. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 48
  3. Upregulation of miR-23a-27a-24-2 cluster induces caspase-dependent and -independent apoptosis in human embryonic kidney cells. (PMID: 19513126) Chhabra R. … Saini N. (PLoS ONE 2009) 3
  4. Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of hepatic nuclear factor 4 alpha. (PMID: 20158877) Koh W. … Tanavde V. (BMC Genomics 2010) 3
  5. miR-24 regulates apoptosis by targeting the open reading frame (ORF) region of FAF1 in cancer cells. (PMID: 20195546) Qin W. … Jin Y. (PLoS ONE 2010) 3

Products for MIR24-2 Gene

Sources for MIR24-2 Gene

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