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Aliases for MIR24-2 Gene

Subcategory (RNA class) for MIR24-2 Gene

lncRNA

Quality Score for this RNA gene is

8.2

Aliases for MIR24-2 Gene

  • MicroRNA 24-2 2 3 5
  • Hsa-Mir-24-2 3
  • MiRNA24-2 3
  • MiR-24-2 3
  • MIRN24-2 3

External Ids for MIR24-2 Gene

ORGUL Members for MIR24-2 Gene

Previous HGNC Symbols for MIR24-2 Gene

  • MIRN24-2

Previous GeneCards Identifiers for MIR24-2 Gene

  • GC19M013845
  • GC19M013851
  • GC19M013947
  • GC19M013860
  • GC19M013865
  • GC19M013870
  • GC19M013876

Summaries for MIR24-2 Gene

Entrez Gene Summary for MIR24-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR24-2 Gene

MIR24-2 (MicroRNA 24-2) is an RNA Gene, and is affiliated with the lncRNA class.

fRNAdb sequence ontologies for MIR24-2 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR24-2

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR24-2 Gene

Genomics for MIR24-2 Gene

Regulatory Elements for MIR24-2 Gene

Enhancers for MIR24-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F013793 0.2 ENCODE 26.8 +40.5 40512 5.5 HDGF PKNOX1 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 MIR24-2 C19orf53 MRI1 MIR23A MIR27A ITGB1P1 FARSA ENSG00000267582 ZSWIM4
GH19F013833 0.6 FANTOM5 ENCODE 14.6 -8.2 -8214 23.1 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 CCDC130 MRI1 TRMT1 ENSG00000267735 DCAF15 MIR181C RFX1 MIR24-2 ZSWIM4 SYCE2
GH19F013747 0.5 ENCODE 14.3 +88.1 88141 2.2 HDGF PKNOX1 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZNF302 ZNF416 CCDC130 MRI1 TRMT1 ENSG00000267735 MIR181C MIR24-2 ZNF333 SYCE2 RPS6P25 NANOS3
GH19F013951 0.2 ENCODE 14.3 -116.5 -116549 2.4 HDGF PKNOX1 WRNIP1 ZFP64 ARID4B SIN3A ZNF2 YY1 ZNF143 FOS MIR24-2 DCAF15 PODNL1
GH19F014000 0.7 FANTOM5 ENCODE 14.3 -167.7 -167741 7.0 CREB3L1 ZFP64 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 MEF2D CCDC130 MIR24-2 RFX1 DCAF15 MRI1 ITGB1P1 LYL1 ZSWIM4 TRMT1 MIR639
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR24-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR24-2 Gene

Chromosome:
19
Start:
13,834,516 bp from pter
End:
13,836,359 bp from pter
Size:
1,844 bases
Orientation:
Minus strand

Genomic View for MIR24-2 Gene

Genes around MIR24-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR24-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR24-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR24-2 Gene

ORGUL Member Location for MIR24-2 Gene

ORGUL Member Location for MIR24-2 gene

Proteins for MIR24-2 Gene

Post-translational modifications for MIR24-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR24-2 Gene

Domains & Families for MIR24-2 Gene

Gene Families for MIR24-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR24-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR24-2 Gene

Function for MIR24-2 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR24-2 Gene

Localization for MIR24-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR24-2 Gene

Pathways & Interactions for MIR24-2 Gene

SuperPathways for MIR24-2 Gene

No Data Available

Interacting Proteins for MIR24-2 Gene

Gene Ontology (GO) - Biological Process for MIR24-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR24-2 Gene

Transcripts for MIR24-2 Gene

fRNAdb Secondary structures for MIR24-2 Gene

  • FR397352

mRNA/cDNA for MIR24-2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR24-2 Gene

No ASD Table

Relevant External Links for MIR24-2 Gene

GeneLoc Exon Structure for
MIR24-2
ECgene alternative splicing isoforms for
MIR24-2

Expression for MIR24-2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR24-2 Gene

This gene is overexpressed in Whole Blood (x4.8).

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR24-2 Gene

Orthologs for MIR24-2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR24-2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-24-2 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-24-2 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-24-2 35
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-24-2 35
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-24-2 35
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir24-2 35
  • 61 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-24 35
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-24-1 35
  • 83 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii mir24-2 35 35
  • 62 (a)
OneToMany
dre-mir-24-1 35
  • 61 (a)
OneToMany
BX664751.1 35
  • 54 (a)
OneToMany
Species where no ortholog for MIR24-2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR24-2 Gene

ENSEMBL:
Gene Tree for MIR24-2 (if available)
TreeFam:
Gene Tree for MIR24-2 (if available)

Paralogs for MIR24-2 Gene

No data available for Paralogs for MIR24-2 Gene

Variants for MIR24-2 Gene

Sequence variations from dbSNP and Humsavar for MIR24-2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10422126 -- 13,837,498(+) CTCAC(A/G)CCTGT upstream-variant-2KB
rs10423627 -- 13,836,955(+) CCTCA(C/T)TGAGC upstream-variant-2KB
rs111251582 -- 13,837,836(+) AGGCT(A/G)GAGTG upstream-variant-2KB
rs114246707 -- 13,838,207(+) CACAG(A/T)GTCTG upstream-variant-2KB
rs115255566 -- 13,837,535(+) CAGGA(A/G)AGTCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR24-2 Gene

Variant ID Type Subtype PubMed ID
nsv833757 CNV loss 17160897
nsv953979 CNV deletion 24416366

Relevant External Links for MIR24-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR24-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR24-2 Gene

Disorders for MIR24-2 Gene

Relevant External Links for MIR24-2

Genetic Association Database (GAD)
MIR24-2
Human Genome Epidemiology (HuGE) Navigator
MIR24-2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR24-2

No disorders were found for MIR24-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR24-2 Gene

Publications for MIR24-2 Gene

  1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y. … Liu P. (Schizophr. Res. 2010) 3 46 64
  2. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 46 64
  3. Identification of valid reference genes for microRNA expression studies in a hepatitis B virus replicating liver cell line. (PMID: 26801621) Jacobsen K.S. … Hogh B. (BMC Res Notes 2016) 3 64
  4. Association of miR-34a-3p/5p, miR-141-3p/5p, and miR-24 in Decidual Natural Killer Cells with Unexplained Recurrent Spontaneous Abortion. (PMID: 26996957) Li D. … Li J. (Med. Sci. Monit. 2016) 3 64
  5. Methylation Status of SP1 Sites within miR-23a-27a-24-2 Promoter Region Influences Laryngeal Cancer Cell Proliferation and Apoptosis. (PMID: 27099864) Wang Y. … Fu W.N. (Biomed Res Int 2016) 3 64

Products for MIR24-2 Gene

Sources for MIR24-2 Gene

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