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Aliases for MIR23C Gene

Subcategory (RNA class) for MIR23C Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR23C Gene

  • MicroRNA 23c 2 3 5
  • Hsa-Mir-23c 3
  • Mir-23c 3

External Ids for MIR23C Gene

Previous GeneCards Identifiers for MIR23C Gene

  • GC0XU901672

Summaries for MIR23C Gene

Entrez Gene Summary for MIR23C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR23C Gene

MIR23C (MicroRNA 23c) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR23C Gene

Genomics for MIR23C Gene

Regulatory Elements for MIR23C Gene

Enhancers for MIR23C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XG020028 0.8 ENCODE 0.4 -12.8 -12757 2.2 ELF3 SOX13 TFAP4 SAP130 MLX ZNF133 ARID4B MAX ZNF384 RAD21 CXorf23 SH3KBP1 MIR23C MAP7D2
GH0XG020060 0.9 FANTOM5 ENCODE 0.3 -44.3 -44337 1.9 MTA2 BHLHE40 REST EBF1 DPF2 RELA IKZF1 RELB IKZF2 CXorf23 MAP7D2 MIR23C
GH0XG020066 1.1 Ensembl ENCODE 0.2 -50.6 -50556 1.8 ZBTB40 RAD21 ZNF143 FOS ZNF654 CEBPB ZEB2 REST MAFF SMARCA4 CXorf23 MAP7D2 SH3KBP1 MIR23C
GH0XG020029 0.5 ENCODE 0.4 -11.6 -11601 0.1 SOX5 MLX ZNF133 TCF7 ZNF644 SH3KBP1 MIR23C MAP7D2
GH0XG020057 0.4 FANTOM5 0.3 -41.0 -40994 0.4 EBF1 MIR23C MAP7D2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR23C on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR23C Gene

Chromosome:
X
Start:
20,017,088 bp from pter
End:
20,017,187 bp from pter
Size:
100 bases
Orientation:
Minus strand

Genomic View for MIR23C Gene

Genes around MIR23C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR23C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR23C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR23C Gene

Proteins for MIR23C Gene

Post-translational modifications for MIR23C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR23C Gene

Domains & Families for MIR23C Gene

Gene Families for MIR23C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR23C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR23C Gene

Function for MIR23C Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR23C Gene

Localization for MIR23C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR23C Gene

Pathways & Interactions for MIR23C Gene

SuperPathways for MIR23C Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR23C: view

Pathways by source for MIR23C Gene

1 KEGG pathway for MIR23C Gene

Interacting Proteins for MIR23C Gene

Gene Ontology (GO) - Biological Process for MIR23C Gene

None

No data available for SIGNOR curated interactions for MIR23C Gene

Drugs & Compounds for MIR23C Gene

No Compound Related Data Available

Transcripts for MIR23C Gene

mRNA/cDNA for MIR23C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR23C Gene

No ASD Table

Relevant External Links for MIR23C Gene

GeneLoc Exon Structure for
MIR23C
ECgene alternative splicing isoforms for
MIR23C

Expression for MIR23C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR23C Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR23C Gene:

MIR23C
genes like me logo Genes that share expression patterns with MIR23C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR23C Gene

Orthologs for MIR23C Gene

Evolution for MIR23C Gene

ENSEMBL:
Gene Tree for MIR23C (if available)
TreeFam:
Gene Tree for MIR23C (if available)

No data available for Orthologs for MIR23C Gene

Paralogs for MIR23C Gene

No data available for Paralogs for MIR23C Gene

Variants for MIR23C Gene

Sequence variations from dbSNP and Humsavar for MIR23C Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000860102 -- 20,019,040(+) TTTCT(C/T)TGTAG intron-variant, upstream-variant-2KB, utr-variant-3-prime
rs1001391347 -- 20,018,351(+) CTCCA(C/T)AATCC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1001976529 -- 20,017,399(+) AGCAT(A/G)TGCCA intron-variant, upstream-variant-2KB
rs1002009101 -- 20,016,884(+) ACCTC(C/T)ATTTC intron-variant, downstream-variant-500B
rs1004165852 -- 20,016,772(+) AGTGA(C/T)TACGA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR23C Gene

Variant ID Type Subtype PubMed ID
esv3573634 CNV loss 25503493

Relevant External Links for MIR23C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR23C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR23C Gene

Disorders for MIR23C Gene

Relevant External Links for MIR23C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR23C

No disorders were found for MIR23C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR23C Gene

Publications for MIR23C Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR23C Gene

Sources for MIR23C Gene

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