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MIR22 host gene (non-protein coding)(Previous name: chromosome 17 open reading frame 91 )
(Previous symbol: C17orf91)
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Aliases
for MIR22HG gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
Subcategory (RNA class): lncRNA
Quality score for this RNA gene is 3
| Aliases |
|---|
| MIR22 Host Gene (Non-Protein Coding)1 2 | | C17orf911 2 3 | | DKFZp686O061591 | | MGC143761 | | Chromosome 17 Open Reading Frame 911 |
| External Ids: | HGNC: 282191 | Entrez Gene: 849812 | Ensembl: ENSG000001865947 | UniProtKB: Q0VDD53 | | ORGUL members: | |
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| NONCODE:n408292 n408293 n408295 n377677 | |
Export aliases for MIR22HG gene to outside databases
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Summaries
for MIR22HG gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MIR22HG gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MIR22HG
Other transcription factors
Search SABiosciences Chromatin IP Primers for MIR22HG
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIR22HG |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.3 Ensembl cytogenetic band: 17p13.3 HGNC cytogenetic band: 17p13.3MIR22HG Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M001616: view genomic region
(about GC identifiers)
Start:
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1,614,798 bp from pter |
End:
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1,620,468 bp from pter |
Size:
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5,671 bases |
Orientation:
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minus strand |
ORGUL member locations:
Legend (see complete legend)
- n408295
- n408293
- n408292
- n377677
1614797 1617182 1619566 chr17
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Proteins
for MIR22HG gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CQ091_HUMAN, Q0VDD5 (See
protein sequence)Recommended Name: Putative uncharacterized protein encoded by MIR22HG Size: 57 amino acids; 6478 Da
Caution: Product of a dubious CDS prediction. May be a non-coding RNA
Secondary accessions: Q0VDD6Explore the universe of human proteins at neXtProt for MIR22HG: NX_Q0VDD5
MIR22HG Protein expression data from MOPED and PaxDb: --
Human Recombinant Protein Products:
MIR22HG Antibody Products:
Assay Products for MIR22HG: |
Protein
Domains /
Families
for MIR22HG gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q0VDD5 |
Function
for MIR22HG gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR22HG |
|
Pathways & Interactions
for MIR22HG gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MIR22HG
|
Drugs & Compounds
for MIR22HG gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MIR22HG
Search CenterWatch for drugs/clinical trials and news about MIR22HG 
|
Transcripts
for MIR22HG gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MIR22HG gene (2 alternative transcripts): NM_001001870.1 NM_032895.2 Unigene Cluster for MIR22HG: MIR22 host gene (non-protein coding) Hs.597755 [show with all ESTs]Unigene Representative Sequence: BX64832112 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000334146(lincRNA)(uc002ftf.3) ENST00000574306(lincRNA)(uc002ftg.3 uc021tni.1 uc021tnj.1)
ENST00000576749(lincRNA) ENST00000570416(lincRNA) ENST00000571595(lincRNA) ENST00000571091(lincRNA) ENST00000573127(lincRNA)
ENST00000576489(lincRNA) ENST00000575626(lincRNA) ENST00000573075(lincRNA) ENST00000574016(lincRNA) ENST00000577164(lincRNA)
Additional cDNA sequence: AF070569.1 BC007813.2 BC070225.1 BC119720.1 BC119721.1 BX640650.1 BX648321.1 NR_028502.1 NR_028503.1 NR_028504.1 NR_028505.1 7 DOTS entries: DT.455644 DT.100776839 DT.100017602 DT.91826492 DT.120948548 DT.120948593 DT.97842858 24/156 AceView cDNA sequences (see all 156): AA434535 CA309565 AI952239 NM_032895 BG482710 BM126997 AI344594 BE710277 CR615473 AA257091 AL545472 CA309715 BQ030155 BE710283 BG289254 AA565303 CA305977 AA443422 AW103633 AW804377 CR591309 BQ129198 BQ029784 BQ183272
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for MIR22HG About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 |
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| SP1: | | | | | | | | | | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for MIR22HG
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Expression
for MIR22HG gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for MIR22HG:none
MIR22HG expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTATGTGATT
About this image
Genevestigator expression for MIR22HG
SOURCE GeneReport for Unigene cluster: Hs.597755
SABiosciences Custom PCR Arrays for MIR22HG
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MIR22HG | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MIR22HG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MIR22HG | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR22HG |
Orthologs
for MIR22HG gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for MIR22HG gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Mir22hg5 |
RIKEN cDNA 2210403K04 gene |
-- |
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11 (45.91 cM) 75461539 |
ENSEMBL Gene Tree for MIR22HG (if available)
TreeFam Gene Tree for MIR22HG (if available) |
Paralogs
for MIR22HG gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MIR22HG gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for MIR22HG (1614798 - 1620468 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MIR22HG: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for MIR22HG gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for MIR22HG gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MIR22HG gene integrated from 9 sources:
(articles sorted by number of sources associating them with MIR22HG) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 3 Yu W.... Gibbs R.A. (1997)
- A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (1996)
- Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. (PubMed id 20705733)1 O'Seaghdha C.M....KAPttgen A. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for MIR22HG gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MIR22HG gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MIR22HG gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MIR22HG gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MIR22HG | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MIR22HG gene:
Search GeneIP for patents involving MIR22HG
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MIR22HG gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MIR22HG | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MIR22HG | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MIR22HG | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MIR22HG | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MIR22HG | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MIR22HG |
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 |  |  |  | |
| | | | Search Tocris compounds for MIR22HG |
| |  |  |  |  | | | | |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MIR22HG |
|  |  |  | | | | Search ThermoFisher Antibodies for MIR22HG |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MIR22HG |
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GeneCards Homepage -
Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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