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Aliases for MIR22HG Gene

Subcategory (RNA class) for MIR22HG Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR22HG Gene

  • MIR22 Host Gene 2 3 5
  • MIR22 Host Gene (Non-Protein Coding) 2 3
  • C17orf91 3 4
  • Chromosome 17 Open Reading Frame 91 2

External Ids for MIR22HG Gene

Previous HGNC Symbols for MIR22HG Gene

  • C17orf91

Previous GeneCards Identifiers for MIR22HG Gene

  • GC17M001616
  • GC17M001618
  • GC17M001623

Summaries for MIR22HG Gene

GeneCards Summary for MIR22HG Gene

MIR22HG (MIR22 Host Gene) is an RNA Gene, and is affiliated with the miRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR22HG Gene

Genomics for MIR22HG Gene

Regulatory Elements for MIR22HG Gene

Enhancers for MIR22HG Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G001807 1.1 ENCODE 17.2 -92.7 -92697 4.9 HDGF PKNOX1 MLX AGO1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SMYD4 MIR22HG RPA1 METTL16 WDR81 MIR22 TLCD2 SERPINF2 SMG6 ENSG00000263345
GH17G001782 1.5 Ensembl ENCODE dbSUPER 11.7 -66.2 -66158 3.1 HDGF FOXA2 PKNOX1 ATF1 ARID4B SIN3A YY1 ZNF121 SLC30A9 ZNF143 SMYD4 SERPINF1 SERPINF2 RPA1 MIR22 MIR22HG WDR81 TLCD2 PIR53033
GH17G001648 1.4 ENCODE dbSUPER 11.9 +67.5 67544 3.8 HDGF FOXA2 PKNOX1 CREB3L1 AGO1 ZFP64 ARID4B SIN3A FEZF1 ZNF2 SMYD4 RPA1 METTL16 RILP TLCD2 MIR22 MIR22HG WDR81 PITPNA SMG6
GH17G001785 1.3 Ensembl ENCODE dbSUPER 11.7 -70.2 -70210 3.4 GTF2F1 TBP JUN MAX SIN3A ZIC2 FOSL1 ZNF121 HIC1 GATA2 SMYD4 SMG6 SERPINF1 SERPINF2 RPA1 MIR22 MIR22HG WDR81 TLCD2 ENSG00000263345
GH17G001778 1.2 Ensembl ENCODE dbSUPER 11.6 -62.5 -62504 2.3 HDGF PKNOX1 NRF1 ZNF76 OSR2 PRDM6 SCRT2 GLIS1 FOXP2 WT1 SMYD4 SERPINF2 TLCD2 MIR22HG WDR81 MIR22 RPA1 SERPINF1 PIR53033 PIR54968
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR22HG on UCSC Golden Path with GeneCards custom track

Promoters for MIR22HG Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000090127 1074 3401 MLX CREB3L1 ZFP64 DMAP1 YBX1 YY1 ZNF143 ZNF263 SP3 NFYC

Genomic Location for MIR22HG Gene

Chromosome:
17
Start:
1,711,493 bp from pter
End:
1,717,174 bp from pter
Size:
5,682 bases
Orientation:
Minus strand

Genomic View for MIR22HG Gene

Genes around MIR22HG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR22HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR22HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR22HG Gene

Proteins for MIR22HG Gene

  • Protein details for MIR22HG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0VDD5-CQ091_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by MIR22HG
    Protein Accession:
    Q0VDD5
    Secondary Accessions:
    • Q0VDD6

    Protein attributes for MIR22HG Gene

    Size:
    57 amino acids
    Molecular mass:
    6478 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MIR22HG Gene

Post-translational modifications for MIR22HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR22HG Gene

Domains & Families for MIR22HG Gene

Gene Families for MIR22HG Gene

Protein Domains for MIR22HG Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR22HG: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR22HG Gene

Function for MIR22HG Gene

Phenotypes for MIR22HG Gene

GenomeRNAi human phenotypes for MIR22HG:
genes like me logo Genes that share phenotypes with MIR22HG: view

Animal Model Products

miRNA for MIR22HG Gene

miRTarBase miRNAs that target MIR22HG

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MIR22HG Gene

Localization for MIR22HG Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR22HG Gene

Pathways & Interactions for MIR22HG Gene

SuperPathways for MIR22HG Gene

No Data Available

Interacting Proteins for MIR22HG Gene

Gene Ontology (GO) - Biological Process for MIR22HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR22HG Gene

Drugs & Compounds for MIR22HG Gene

No Compound Related Data Available

Transcripts for MIR22HG Gene

Unigene Clusters for MIR22HG Gene

MIR22 host gene (non-protein coding):
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR22HG Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4
SP1: - -
SP2:
SP3: -

Relevant External Links for MIR22HG Gene

GeneLoc Exon Structure for
MIR22HG
ECgene alternative splicing isoforms for
MIR22HG

Expression for MIR22HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR22HG Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR22HG Gene:

MIR22HG

SOURCE GeneReport for Unigene cluster for MIR22HG Gene:

Hs.597755
genes like me logo Genes that share expression patterns with MIR22HG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR22HG Gene

Orthologs for MIR22HG Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR22HG Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-22 35
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-22 35
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir22 35
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-22 35
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-22 35
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-22 35
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-22 35
  • 75 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-22a 35
  • 81 (a)
OneToMany
CU442763.1 35
  • 72 (a)
OneToMany
dre-mir-22b 35
  • 68 (a)
OneToMany
Species where no ortholog for MIR22HG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR22HG Gene

ENSEMBL:
Gene Tree for MIR22HG (if available)
TreeFam:
Gene Tree for MIR22HG (if available)

Paralogs for MIR22HG Gene

No data available for Paralogs for MIR22HG Gene

Variants for MIR22HG Gene

Sequence variations from dbSNP and Humsavar for MIR22HG Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000073610 -- 1,716,125(+) TCACA(C/G)CCACC intron-variant, upstream-variant-2KB
rs1000140507 -- 1,717,177(+) CTTAG(A/G)GAAGA intron-variant, upstream-variant-2KB
rs1000631440 -- 1,715,013(+) AATTC(C/T)GAAAC intron-variant, upstream-variant-2KB
rs1000659602 -- 1,712,140(+) TCTTA(-/T)TTTTT nc-transcript-variant, upstream-variant-2KB
rs1001587850 -- 1,717,243(+) GTCTA(C/G)ATGAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR22HG Gene

Variant ID Type Subtype PubMed ID
nsv470568 CNV loss 18288195
nsv516886 CNV loss 19592680
nsv827856 CNV gain 20364138
nsv833335 CNV gain+loss 17160897
nsv9490 CNV loss 18304495

Relevant External Links for MIR22HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR22HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR22HG Gene

Disorders for MIR22HG Gene

Relevant External Links for MIR22HG

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR22HG

No disorders were found for MIR22HG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR22HG Gene

Publications for MIR22HG Gene

  1. Integrated analysis profiles of long non-coding RNAs reveal potential biomarkers of drug resistance in lung cancer. (PMID: 28415620) Xue W. … Zhao J. (Oncotarget 2017) 2 3 64
  2. Identification of short-lived long non-coding RNAs as surrogate indicators for chemical stress response. (PMID: 24036268) Tani H. … Torimura M. (Biochem. Biophys. Res. Commun. 2013) 2 3 64
  3. Long noncoding RNA C17orf91 is a potential prognostic marker and functions as an oncogene in ovarian cancer. (PMID: 27535740) Li J. … Lu X. (J Ovarian Res 2016) 3 64
  4. Long non-coding RNAs as surrogate indicators for chemical stress responses in human-induced pluripotent stem cells. (PMID: 25171338) Tani H. … Torimura M. (PLoS ONE 2014) 3 64
  5. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. (PMID: 23022100) Franceschini N. … Morris A.P. (Am. J. Hum. Genet. 2012) 3 64

Products for MIR22HG Gene

Sources for MIR22HG Gene

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