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Aliases for MIR2276 Gene

Subcategory (RNA class) for MIR2276 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR2276 Gene

  • MicroRNA 2276 2 3 5
  • Hsa-Mir-2276 3

External Ids for MIR2276 Gene

Previous GeneCards Identifiers for MIR2276 Gene

  • GC00U927818
  • GC13U900688
  • GC13P024736
  • GC13P005548

Summaries for MIR2276 Gene

Entrez Gene Summary for MIR2276 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2276 Gene

MIR2276 (MicroRNA 2276) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2276 Gene

Genomics for MIR2276 Gene

Regulatory Elements for MIR2276 Gene

Enhancers for MIR2276 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13F024050 1.4 FANTOM5 Ensembl ENCODE 11.5 -111.6 -111575 1.5 PTRF ZNF766 FOS ETV6 HDAC8 ZNF592 CREB3 MEF2D TFDP1 ZNF589 SPATA13 MIR2276 SPATA13-AS1 PARP4 PIR59399 IPO7P2
GH13F024181 1.2 Ensembl ENCODE 12.6 +21.6 21578 4.3 ARID4B DMAP1 ZNF48 YY1 KAT8 MIER3 ETV4 KDM1A HBP1 TEAD3 MIR2276 SPATA13 PIR40383 SPATA13-AS1
GH13F024214 1.2 Ensembl ENCODE 12.1 +54.4 54375 4.4 ELF3 MLX ARID4B ZNF48 RAD21 ZNF2 RARA YY1 ZNF366 EGR2 MIR2276 SPATA13 SPATA13-AS1 PIR40383
GH13F024220 1.1 Ensembl ENCODE 12.1 +58.3 58339 2.1 CTCF SAP130 WRNIP1 ZFP64 ARID4B MAX RAD21 ZNF316 GATA3 SMC3 MIR2276 SPATA13 SPATA13-AS1 PIR40383
GH13F024124 1.1 Ensembl ENCODE 11.6 -35.1 -35140 5.8 PKNOX1 TBL1XR1 BMI1 FOS MIER2 REST TBX21 NR2F2 ZNF217 MBD2 MIR2276 SPATA13 SPATA13-AS1 IPO7P2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR2276 on UCSC Golden Path with GeneCards custom track

Promoters for MIR2276 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000513020 -1316 2201 TBP SIN3A FEZF1 ZNF48 RAD21 GLIS2 SCRT2 EGR2 ZNF362 SP3

Genomic Location for MIR2276 Gene

Chromosome:
13
Start:
24,162,416 bp from pter
End:
24,162,504 bp from pter
Size:
89 bases
Orientation:
Plus strand

Genomic View for MIR2276 Gene

Genes around MIR2276 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2276 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2276 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2276 Gene

Proteins for MIR2276 Gene

Post-translational modifications for MIR2276 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2276 Gene

Domains & Families for MIR2276 Gene

Gene Families for MIR2276 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2276: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2276 Gene

Function for MIR2276 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2276 Gene

Localization for MIR2276 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2276 Gene

Pathways & Interactions for MIR2276 Gene

SuperPathways for MIR2276 Gene

No Data Available

Interacting Proteins for MIR2276 Gene

Gene Ontology (GO) - Biological Process for MIR2276 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR2276 Gene

Transcripts for MIR2276 Gene

mRNA/cDNA for MIR2276 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2276 Gene

No ASD Table

Relevant External Links for MIR2276 Gene

GeneLoc Exon Structure for
MIR2276
ECgene alternative splicing isoforms for
MIR2276

Expression for MIR2276 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR2276 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2276 Gene:

MIR2276
genes like me logo Genes that share expression patterns with MIR2276: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR2276 Gene

Orthologs for MIR2276 Gene

Evolution for MIR2276 Gene

ENSEMBL:
Gene Tree for MIR2276 (if available)
TreeFam:
Gene Tree for MIR2276 (if available)

No data available for Orthologs for MIR2276 Gene

Paralogs for MIR2276 Gene

No data available for Paralogs for MIR2276 Gene

Variants for MIR2276 Gene

Sequence variations from dbSNP and Humsavar for MIR2276 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs112561945 -- 24,160,682(+) GGGCG(C/T)GGCCT intron-variant, upstream-variant-2KB
rs112604340 -- 24,160,950(+) CGGGC(G/T)CGCGG intron-variant, upstream-variant-2KB
rs115395221 -- 24,162,207(+) TTCTC(C/T)CATCT intron-variant, upstream-variant-2KB
rs116804943 -- 24,162,611(+) AATGT(C/T)AATAT intron-variant, downstream-variant-500B
rs12863941 -- 24,161,597(+) TGCTG(C/T)CAGCG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2276 Gene

Variant ID Type Subtype PubMed ID
nsv561341 CNV loss 21841781
nsv561292 CNV loss 21841781
nsv525965 CNV gain 19592680
nsv509499 CNV insertion 20534489
nsv455837 CNV gain 19166990
nsv1151909 OTHER inversion 26484159
nsv1140246 OTHER inversion 24896259
nsv1078303 OTHER inversion 25765185
nsv1050731 CNV gain 25217958
esv5325 OTHER complex 18987735
esv3892311 CNV gain 25118596
esv3631540 CNV gain 21293372
esv3580576 CNV loss 25503493
esv2751137 CNV gain 17911159
esv2751136 CNV loss 17911159
esv2422502 CNV duplication 17116639
esv2422202 CNV duplication 17116639
dgv3084n54 CNV gain 21841781
dgv1615n100 CNV gain 25217958

Relevant External Links for MIR2276 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2276

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2276 Gene

Disorders for MIR2276 Gene

Relevant External Links for MIR2276

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR2276

No disorders were found for MIR2276 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2276 Gene

Publications for MIR2276 Gene

  1. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 64
  2. Identification and analysis of miRNAs in human breast cancer and teratoma samples using deep sequencing. (PMID: 19508715) Nygaard S. … Litman T. (BMC Med Genomics 2009) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR2276 Gene

Sources for MIR2276 Gene

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