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Aliases for MIR22 Gene

Subcategory (RNA class) for MIR22 Gene


Quality Score for this RNA gene is


Aliases for MIR22 Gene

  • MicroRNA 22 2 3 5
  • Hsa-Mir-22 3
  • MiR-22 3
  • MIRN22 3

External Ids for MIR22 Gene

Previous HGNC Symbols for MIR22 Gene

  • MIRN22

Previous GeneCards Identifiers for MIR22 Gene

  • GC17M001571
  • GC17M001617
  • GC17M001619
  • GC17M001624

Summaries for MIR22 Gene

Entrez Gene Summary for MIR22 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR22 Gene

MIR22 (MicroRNA 22) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR22 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR22

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR22 Gene

Genomics for MIR22 Gene

Regulatory Elements for MIR22 Gene

Enhancers for MIR22 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR22 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR22 Gene

1,713,895 bp from pter
1,714,005 bp from pter
111 bases
Minus strand

Genomic View for MIR22 Gene

Genes around MIR22 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR22 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR22 Gene

ORGUL Member Location for MIR22 Gene

ORGUL Member Location for MIR22 gene

Proteins for MIR22 Gene

Post-translational modifications for MIR22 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR22 Gene

Domains & Families for MIR22 Gene

Gene Families for MIR22 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR22: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR22 Gene

Function for MIR22 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR22 Gene

Localization for MIR22 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR22 Gene

Pathways & Interactions for MIR22 Gene

SuperPathways for MIR22 Gene

No Data Available

Interacting Proteins for MIR22 Gene

Gene Ontology (GO) - Biological Process for MIR22 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR22 Gene

Drugs & Compounds for MIR22 Gene

No Compound Related Data Available

Transcripts for MIR22 Gene

fRNAdb Secondary structures for MIR22 Gene

  • FR130692

mRNA/cDNA for MIR22 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR22 Gene

No ASD Table

Relevant External Links for MIR22 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR22 Gene

mRNA expression in normal human tissues for MIR22 Gene

genes like me logo Genes that share expression patterns with MIR22: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR22 Gene

Orthologs for MIR22 Gene

Evolution for MIR22 Gene

Gene Tree for MIR22 (if available)
Gene Tree for MIR22 (if available)

No data available for Orthologs for MIR22 Gene

Paralogs for MIR22 Gene

No data available for Paralogs for MIR22 Gene

Variants for MIR22 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR22 Gene

Variant ID Type Subtype PubMed ID
nsv907502 CNV Loss 21882294
nsv907511 CNV Loss 21882294
nsv907515 CNV Loss 21882294
nsv9490 CNV Loss 18304495
nsv470568 CNV Loss 18288195
nsv516886 CNV Loss 19592680
dgv3033n71 CNV Loss 21882294
nsv833335 CNV Gain+Loss 17160897

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR22 Gene

Disorders for MIR22 Gene

Relevant External Links for MIR22

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR22 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR22 Gene

Publications for MIR22 Gene

  1. Alpha-enolase is a potential prognostic marker in clear cell renal cell carcinoma. (PMID: 26037892) White-Al Habeeb N.M. … Yousef G.M. (Clin. Exp. Metastasis 2015) 3 67
  2. Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation. (PMID: 24825182) Palacios F. … Oppezzo P. (Leukemia 2015) 3
  3. microRNA-22 acts as a metastasis suppressor by targeting metadherin in gastric cancer. (PMID: 25323629) Tang Y. … Su Q. (Mol Med Rep 2015) 3
  4. MicroRNA-22-3p is down-regulated in the plasma of Han Chinese patients with premature ovarian failure. (PMID: 25585503) Dang Y. … Chen Z.J. (Fertil. Steril. 2015) 3
  5. MiR-22-silenced cyclin A expression in colon and liver cancer cells is regulated by bile acid receptor. (PMID: 25596928) Yang F. … Wan Y.J. (J. Biol. Chem. 2015) 3

Products for MIR22 Gene

Sources for MIR22 Gene