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Aliases for MIR219B Gene

Subcategory (RNA class) for MIR219B Gene

miRNA

Quality Score for this RNA gene is

10.2

Aliases for MIR219B Gene

  • MicroRNA 219b 2 3
  • MicroRNA 2964a 2 3
  • Hsa-Mir-2964a 3
  • Hsa-Mir-219b 3
  • MIR2964A 3

External Ids for MIR219B Gene

Previous HGNC Symbols for MIR219B Gene

  • MIR2964A

Previous GeneCards Identifiers for MIR219B Gene

  • GC09P131158

Summaries for MIR219B Gene

Entrez Gene Summary for MIR219B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR219B Gene

MIR219B (MicroRNA 219b) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR219B Gene - the ORGUL cluster for this gene includes several descriptions:

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR219B

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR219B Gene

Genomics for MIR219B Gene

Genomic Location for MIR219B Gene

Start:
128,392,621 bp from pter
End:
128,392,708 bp from pter
Size:
88 bases
Orientation:
Plus strand

Genomic View for MIR219B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR219B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR219B Gene

ORGUL Member Location for MIR219B Gene

ORGUL Member Location for MIR219B gene

No data available for Regulatory Elements for MIR219B Gene

Proteins for MIR219B Gene

Post-translational modifications for MIR219B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR219B Gene

Domains for MIR219B Gene

Gene Families for MIR219B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR219B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR219B Gene

Function for MIR219B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR219B Gene

Localization for MIR219B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR219B Gene

Pathways for MIR219B Gene

SuperPathways for MIR219B Gene

No Data Available

Interacting Proteins for MIR219B Gene

Gene Ontology (GO) - Biological Process for MIR219B Gene

None

No data available for Pathways by source for MIR219B Gene

Transcripts for MIR219B Gene

fRNAdb Secondary structures for MIR219B Gene

  • hsa-miR-219a-2-3p_MIMAT0004675_Homo_sapiens_miR-219a-2-3p_mature
  • FR282263
  • hsa-mir-219a-2_MI0000740_Homo_sapiens_miR-219a-2_stem-loop_hairpin

mRNA/cDNA for MIR219B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR219B Gene

No ASD Table

Relevant External Links for MIR219B Gene

GeneLoc Exon Structure for
MIR219B
ECgene alternative splicing isoforms for
MIR219B

Expression for MIR219B Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR219B Gene

Orthologs for MIR219B Gene

Evolution for MIR219B Gene

ENSEMBL:
Gene Tree for MIR219B (if available)
TreeFam:
Gene Tree for MIR219B (if available)

No data available for Orthologs for MIR219B Gene

Paralogs for MIR219B Gene

No data available for Paralogs for MIR219B Gene

Variants for MIR219B Gene

Relevant External Links for MIR219B Gene

HapMap Linkage Disequilibrium report
MIR219B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR219B Gene

Disorders for MIR219B Gene

No disorders were found for MIR219B Gene.

No data available for UniProtKB/Swiss-Prot for MIR219B Gene

Publications for MIR219B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3
  3. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3

Products for MIR219B Gene

Sources for MIR219B Gene

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