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Aliases for MIR219A2 Gene

Subcategory (RNA class) for MIR219A2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR219A2 Gene

  • MicroRNA 219a-2 2 3 5
  • MicroRNA 219-2 2 3
  • Hsa-Mir-219a-2 3
  • Hsa-Mir-219-2 3
  • Mir-219a-2 3
  • MIRN219-2 3
  • MIR219-2 3

External Ids for MIR219A2 Gene

Previous HGNC Symbols for MIR219A2 Gene

  • MIRN219-2
  • MIR219-2

Previous GeneCards Identifiers for MIR219A2 Gene

  • GC09M131156

Summaries for MIR219A2 Gene

Entrez Gene Summary for MIR219A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR219A2 Gene

MIR219A2 (MicroRNA 219a-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR219A2 Gene

Genomics for MIR219A2 Gene

Regulatory Elements for MIR219A2 Gene

Enhancers for MIR219A2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G128396 0.8 Ensembl dbSUPER 0.7 -4.6 -4557 0.8 MCM7 SUZ12 POLR2A CBX2 KDM1A EZH2 ZKSCAN1 CERCAM GC09M128394 MIR219A2
GH09G128398 0.8 ENCODE dbSUPER 0.7 -0.7 -673 0.1 POLR2A SUZ12 TEAD4 EZH2 GC09M128394 MIR219A2 CERCAM
GH09G128393 0.6 dbSUPER 0.7 -1.9 -1873 1.8 SUZ12 ZBTB8A REST ZNF579 GLIS1 KDM1A FOXP2 FOS EZH2 DNM1 MIR219A2 GC09M128394 CERCAM
GH09G128406 0.9 ENCODE dbSUPER 0.4 -14.3 -14343 0.2 TFAP4 FOXA2 RCOR2 TEAD4 ZMYM3 KDM1A PPARG TEAD3 CERCAM GC09M128394 MIR219A2
GH09G128395 0.5 dbSUPER 0.7 -0.2 -167 0.2 CBX8 SUZ12 POLR2A CBX2 EZH2 GC09M128394 MIR219A2 CERCAM
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR219A2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR219A2 Gene

Chromosome:
9
Start:
128,392,618 bp from pter
End:
128,392,714 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR219A2 Gene

Genes around MIR219A2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR219A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR219A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR219A2 Gene

Proteins for MIR219A2 Gene

Post-translational modifications for MIR219A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR219A2 Gene

Domains & Families for MIR219A2 Gene

Gene Families for MIR219A2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR219A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR219A2 Gene

Function for MIR219A2 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR219A2 Gene

Localization for MIR219A2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR219A2 Gene

Pathways & Interactions for MIR219A2 Gene

genes like me logo Genes that share pathways with MIR219A2: view

Pathways by source for MIR219A2 Gene

1 BioSystems pathway for MIR219A2 Gene

Interacting Proteins for MIR219A2 Gene

Gene Ontology (GO) - Biological Process for MIR219A2 Gene

None

No data available for SIGNOR curated interactions for MIR219A2 Gene

Drugs & Compounds for MIR219A2 Gene

No Compound Related Data Available

Transcripts for MIR219A2 Gene

mRNA/cDNA for MIR219A2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR219A2 Gene

No ASD Table

Relevant External Links for MIR219A2 Gene

GeneLoc Exon Structure for
MIR219A2
ECgene alternative splicing isoforms for
MIR219A2

Expression for MIR219A2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR219A2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR219A2 Gene:

MIR219A2
genes like me logo Genes that share expression patterns with MIR219A2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR219A2 Gene

Orthologs for MIR219A2 Gene

Evolution for MIR219A2 Gene

ENSEMBL:
Gene Tree for MIR219A2 (if available)
TreeFam:
Gene Tree for MIR219A2 (if available)

No data available for Orthologs for MIR219A2 Gene

Paralogs for MIR219A2 Gene

No data available for Paralogs for MIR219A2 Gene

Variants for MIR219A2 Gene

Sequence variations from dbSNP and Humsavar for MIR219A2 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000157282 -- 128,393,007(+) ACTCC(C/G)CTCTC downstream-variant-500B, upstream-variant-2KB
rs1004051074 -- 128,392,622(+) GCCCG(A/G)AGCTC nc-transcript-variant
rs1004103312 -- 128,392,367(+) GTGCC(A/G)GCTTC downstream-variant-500B, upstream-variant-2KB
rs1004597073 -- 128,394,432(+) CCTCT(C/G)TCCTG upstream-variant-2KB
rs1005055092 -- 128,394,132(+) GGGGC(A/G)TGGAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR219A2 Gene

Variant ID Type Subtype PubMed ID
nsv831728 CNV loss 17160897

Relevant External Links for MIR219A2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR219A2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR219A2 Gene

Disorders for MIR219A2 Gene

Relevant External Links for MIR219A2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR219A2

No disorders were found for MIR219A2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR219A2 Gene

Publications for MIR219A2 Gene

  1. The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. (PMID: 26965827) Murai K. … Shi Y. (Nat Commun 2016) 3 64
  2. Suppression of MicroRNA-219-5p Activates Keratinocyte Growth Factor to Mitigate Severity of Experimental Cirrhosis. (PMID: 27855391) Chen L. … Li T. (Cell. Physiol. Biochem. 2016) 3 64
  3. MicroRNA-219-2-3p functions as a tumor suppressor in gastric cancer and is regulated by DNA methylation. (PMID: 23637748) Lei H. … Li Y. (PLoS ONE 2013) 3 64
  4. Self-limited versus delayed resolution of acute inflammation: temporal regulation of pro-resolving mediators and microRNA. (PMID: 22957142) Fredman G. … Serhan C.N. (Sci Rep 2012) 3 64
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64

Products for MIR219A2 Gene

Sources for MIR219A2 Gene

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