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Aliases for MIR217 Gene

Subcategory (RNA class) for MIR217 Gene


Quality Score for this RNA gene is


Aliases for MIR217 Gene

  • MicroRNA 217 2 3 5
  • Hsa-Mir-217 3
  • Mir-217 3
  • MIRN217 3

External Ids for MIR217 Gene

Previous HGNC Symbols for MIR217 Gene

  • MIRN217

Previous GeneCards Identifiers for MIR217 Gene

  • GC02M056064
  • GC02M056210

Summaries for MIR217 Gene

Entrez Gene Summary for MIR217 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR217 Gene

MIR217 (MicroRNA 217) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR217 Gene

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

View fRNAdb secondary structures for MIR217

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR217 Gene

Genomics for MIR217 Gene

Regulatory Elements for MIR217 Gene

Enhancers for MIR217 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR217 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR217 Gene

55,982,952 bp from pter
55,983,076 bp from pter
125 bases
Minus strand

Genomic View for MIR217 Gene

Genes around MIR217 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR217 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR217 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR217 Gene

ORGUL Member Location for MIR217 Gene

ORGUL Member Location for MIR217 gene

Proteins for MIR217 Gene

Post-translational modifications for MIR217 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR217 Gene

Domains & Families for MIR217 Gene

Gene Families for MIR217 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR217: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR217 Gene

Function for MIR217 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR217 Gene

Localization for MIR217 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR217 Gene

Pathways & Interactions for MIR217 Gene

SuperPathways for MIR217 Gene

No Data Available

Interacting Proteins for MIR217 Gene

Gene Ontology (GO) - Biological Process for MIR217 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR217 Gene

Drugs & Compounds for MIR217 Gene

No Compound Related Data Available

Transcripts for MIR217 Gene

fRNAdb Secondary structures for MIR217 Gene

  • FR232136

mRNA/cDNA for MIR217 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR217 Gene

No ASD Table

Relevant External Links for MIR217 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR217 Gene

mRNA expression in normal human tissues for MIR217 Gene

genes like me logo Genes that share expression patterns with MIR217: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR217 Gene

Orthologs for MIR217 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR217 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-217 36
  • 95 (a)
(Canis familiaris)
Mammalia cfa-mir-217 36
  • 96 (a)
(Monodelphis domestica)
Mammalia mdo-mir-217 36
  • 94 (a)
(Mus musculus)
Mammalia Mir217 36
  • 85 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-217 36
  • 85 (a)
oan-mir-217 36
  • 85 (a)
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
ptr-mir-217 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-217 36
  • 93 (a)
(Anolis carolinensis)
Reptilia aca-mir-217 36
  • 85 (a)
(Danio rerio)
Actinopterygii dre-mir-217 36
  • 80 (a)
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-217 36
  • 51 (a)
Species with no ortholog for MIR217:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR217 Gene

Gene Tree for MIR217 (if available)
Gene Tree for MIR217 (if available)

Paralogs for MIR217 Gene

No data available for Paralogs for MIR217 Gene

Variants for MIR217 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR217 Gene

Variant ID Type Subtype PubMed ID
dgv1186e1 CNV Complex 17122850

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR217 Gene

Disorders for MIR217 Gene

Relevant External Links for MIR217

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR217 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR217 Gene

Publications for MIR217 Gene

  1. Silencing of long noncoding RNA MALAT1 by miR-101 and miR-217 inhibits proliferation, migration, and invasion of esophageal squamous cell carcinoma cells. (PMID: 25538231) Wang X. … Yang M. (J. Biol. Chem. 2015) 3 67
  2. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 1 3
  3. Cigarette smoke mediates epigenetic repression of miR-217 during esophageal adenocarcinogenesis. (PMID: 25703328) Xi S. … Schrump D.S. (Oncogene 2015) 3
  4. MiR-217 mediates the protective effects of the dopamine D2 receptor on fibrosis in human renal proximal tubule cells. (PMID: 25801876) Han F. … Armando I. (Hypertension 2015) 3
  5. microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer. (PMID: 25869101) Chen D.L. … Xu R.H. (Oncotarget 2015) 3

Products for MIR217 Gene

Sources for MIR217 Gene