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Aliases for MIR214 Gene

Subcategory (RNA class) for MIR214 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR214 Gene

  • MicroRNA 214 2 3
  • DNM3 Opposite Strand/Antisense RNA 5
  • Hsa-Mir-214 3
  • MiRNA214 3
  • Mir-214 3
  • MIRN214 3
  • DNM3OS 5

External Ids for MIR214 Gene

Previous HGNC Symbols for MIR214 Gene

  • MIRN214

Previous GeneCards Identifiers for MIR214 Gene

  • GC01M170375
  • GC01M172180
  • GC01M172182
  • GC01M172188
  • GC01M172192
  • GC01M172198

Summaries for MIR214 Gene

Entrez Gene Summary for MIR214 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR214 Gene

MIR214 (MicroRNA 214) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and miRs in Muscle Cell Differentiation.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR214 Gene

Genomics for MIR214 Gene

Regulatory Elements for MIR214 Gene

Enhancers for MIR214 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR214 on UCSC Golden Path with GeneCards custom track

Promoters for MIR214 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MIR214 Gene

Chromosome:
1
Start:
172,136,531 bp from pter
End:
172,144,794 bp from pter
Size:
8,264 bases
Orientation:
Minus strand

Genomic View for MIR214 Gene

Genes around MIR214 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR214 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR214 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR214 Gene

ORGUL Member Location for MIR214 Gene

ORGUL Member Location for MIR214 gene

Proteins for MIR214 Gene

Post-translational modifications for MIR214 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR214 Gene

Domains & Families for MIR214 Gene

Gene Families for MIR214 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR214: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR214 Gene

Function for MIR214 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR214 Gene

Localization for MIR214 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR214 Gene

Pathways & Interactions for MIR214 Gene

genes like me logo Genes that share pathways with MIR214: view

Pathways by source for MIR214 Gene

Interacting Proteins for MIR214 Gene

Gene Ontology (GO) - Biological Process for MIR214 Gene

None

No data available for SIGNOR curated interactions for MIR214 Gene

Drugs & Compounds for MIR214 Gene

No Compound Related Data Available

Transcripts for MIR214 Gene

mRNA/cDNA for MIR214 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR214 Gene

No ASD Table

Relevant External Links for MIR214 Gene

GeneLoc Exon Structure for
MIR214
ECgene alternative splicing isoforms for
MIR214

Expression for MIR214 Gene

mRNA expression in normal human tissues for MIR214 Gene

mRNA differential expression in normal tissues according to GTEx for MIR214 Gene

This gene is overexpressed in Spleen (x6.0) and Ovary (x5.4).

NURSA nuclear receptor signaling pathways regulating expression of MIR214 Gene:

MIR214
genes like me logo Genes that share expression patterns with MIR214: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR214 Gene

Orthologs for MIR214 Gene

Evolution for MIR214 Gene

ENSEMBL:
Gene Tree for MIR214 (if available)
TreeFam:
Gene Tree for MIR214 (if available)

No data available for Orthologs for MIR214 Gene

Paralogs for MIR214 Gene

No data available for Paralogs for MIR214 Gene

Variants for MIR214 Gene

Relevant External Links for MIR214 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR214

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR214 Gene

Disorders for MIR214 Gene

Relevant External Links for MIR214

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR214

No disorders were found for MIR214 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR214 Gene

Publications for MIR214 Gene

  1. MicroRNA-214 Inhibits Left Ventricular Remodeling in an Acute Myocardial Infarction Rat Model by Suppressing Cellular Apoptosis via the Phosphatase and Tensin Homolog (PTEN). (PMID: 26973267) Yang X. … Dong S. (Int Heart J 2016) 3 65
  2. MicroRNA-214 Is Upregulated in Heart Failure Patients and Suppresses XBP1-Mediated Endothelial Cells Angiogenesis. (PMID: 25656649) Duan Q. … Wang D.W. (J. Cell. Physiol. 2015) 3 65
  3. MicroRNA-214 suppresses oncogenesis and exerts impact on prognosis by targeting PDRG1 in bladder cancer. (PMID: 25706919) Wang J. … Wang C. (PLoS ONE 2015) 3 65
  4. Cantharidin inhibits cell proliferation and promotes apoptosis in tongue squamous cell carcinoma through suppression of miR-214 and regulation of p53 and Bcl-2/Bax. (PMID: 25962755) Tian X. … Wang L. (Oncol. Rep. 2015) 3 65
  5. Downregulation of urinary cell-free microRNA-214 as a diagnostic and prognostic biomarker in bladder cancer. (PMID: 25975233) Wang J. … Wang C. (J Surg Oncol 2015) 3 65

Products for MIR214 Gene

Sources for MIR214 Gene

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