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Aliases for MIR2117 Gene

Subcategory (RNA class) for MIR2117 Gene


Quality Score for this RNA gene is


Aliases for MIR2117 Gene

  • MicroRNA 2117 2 3 5
  • Hsa-Mir-2117 3

External Ids for MIR2117 Gene

Previous GeneCards Identifiers for MIR2117 Gene

  • GC00U925410
  • GC17U901292
  • GC17P041522
  • GC17P037287

Summaries for MIR2117 Gene

Entrez Gene Summary for MIR2117 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2117 Gene

MIR2117 (MicroRNA 2117) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2117 Gene

Genomics for MIR2117 Gene

Regulatory Elements for MIR2117 Gene

Enhancers for MIR2117 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G043524 1.4 ENCODE dbSUPER 10 +83.8 83845 7.7 PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 FEZF1 ZNF2 YY1 ETV4 RPL29P31 MEOX1 MIR2117HG RNU6-406P MIR2117 SOST GC17P043522 PIR45394 ENSG00000267747
GH17G043406 1.2 Ensembl ENCODE dbSUPER 11.3 -37.3 -37306 1.8 CTCF TAL1 TCF12 ZFHX2 POLR2A NCOR1 NR2F6 NFE2 MAFK NFE2L2 MIR2117 RNU6-406P MEOX1 ETV4 LINC00910 RETREG3 RNU6-470P ARL4D
GH17G043583 1.3 Ensembl ENCODE 9.9 +139.8 139810 2.1 FOXA2 ARNT MLX ARID4B SIN3A ZNF2 ZNF143 ZNF207 DEK ZNF263 ETV4 MEOX1 GPATCH8 DHX8 SOST MIR2117 RNU6-406P ENSG00000278109
GH17G043350 1.2 FANTOM5 dbSUPER 9.8 -93.7 -93739 0.3 HDAC1 PKNOX1 ATF1 MLX GATA2 FOS CREM USF2 ZEB2 RAD51 RNU6-1137P DHX8 LINC00910 RNU2-4P RNU6-406P MIR2117 GC17P043358 LINC00854
GH17G043582 1 Ensembl ENCODE 9.9 +136.9 136927 0.9 SOX13 SAP130 RAD21 ZNF48 RARA NCOR1 NR2F6 TCF7L2 GATAD2A MAZ ETV4 MEOX1 SOST MIR2117 RNU6-406P ENSG00000278109
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR2117 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR2117 Gene

43,444,806 bp from pter
43,444,885 bp from pter
80 bases
Plus strand

Genomic View for MIR2117 Gene

Genes around MIR2117 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2117 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2117 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2117 Gene

Proteins for MIR2117 Gene

Post-translational modifications for MIR2117 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2117 Gene

Domains & Families for MIR2117 Gene

Gene Families for MIR2117 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2117: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2117 Gene

Function for MIR2117 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2117 Gene

Localization for MIR2117 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2117 Gene

Pathways & Interactions for MIR2117 Gene

SuperPathways for MIR2117 Gene

No Data Available

Interacting Proteins for MIR2117 Gene

Gene Ontology (GO) - Biological Process for MIR2117 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR2117 Gene

Drugs & Compounds for MIR2117 Gene

No Compound Related Data Available

Transcripts for MIR2117 Gene

mRNA/cDNA for MIR2117 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2117 Gene

No ASD Table

Relevant External Links for MIR2117 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR2117 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR2117 Gene

mRNA differential expression in normal tissues according to GTEx for MIR2117 Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x18.2) and Skin - Not Sun Exposed (Suprapubic) (x16.7).

NURSA nuclear receptor signaling pathways regulating expression of MIR2117 Gene:

genes like me logo Genes that share expression patterns with MIR2117: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR2117 Gene

Orthologs for MIR2117 Gene

Evolution for MIR2117 Gene

Gene Tree for MIR2117 (if available)
Gene Tree for MIR2117 (if available)

No data available for Orthologs for MIR2117 Gene

Paralogs for MIR2117 Gene

No data available for Paralogs for MIR2117 Gene

Variants for MIR2117 Gene

Sequence variations from dbSNP and Humsavar for MIR2117 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000417205 -- 43,445,330(+) TTTTT(C/T)ATACT downstream-variant-500B
rs1001332665 -- 43,444,265(+) CGATA(A/C)ATGCC upstream-variant-2KB
rs1001759387 -- 43,444,010(+) GCCCT(A/G)GTGTC upstream-variant-2KB
rs1002655106 -- 43,443,577(+) CTCAC(G/T)GCAGA upstream-variant-2KB
rs1002677548 -- 43,444,148(+) ATCTA(C/G)AACCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2117 Gene

Variant ID Type Subtype PubMed ID
esv2761959 CNV gain 21179565
esv3640625 CNV gain 21293372
nsv1060861 CNV gain 25217958
nsv1065802 CNV gain 25217958
nsv1146669 OTHER inversion 26484159
nsv470588 CNV gain 18288195
nsv833451 CNV loss 17160897
nsv833453 CNV gain+loss 17160897

Relevant External Links for MIR2117 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2117 Gene

Disorders for MIR2117 Gene

Relevant External Links for MIR2117

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR2117 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2117 Gene

Publications for MIR2117 Gene

  1. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. (PMID: 19390579) Wyman S.K. … Tewari M. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR2117 Gene

Sources for MIR2117 Gene

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