Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR2117 Gene

Subcategory (RNA class) for MIR2117 Gene


Quality Score for this RNA gene is


Aliases for MIR2117 Gene

  • MicroRNA 2117 2 3
  • MIR2117 Host Gene 5
  • Hsa-Mir-2117 3
  • MIR2117HG 5

External Ids for MIR2117 Gene

Previous GeneCards Identifiers for MIR2117 Gene

  • GC00U925410
  • GC17U901292
  • GC17P041522
  • GC17P037287

Summaries for MIR2117 Gene

Entrez Gene Summary for MIR2117 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2117 Gene

MIR2117 (MicroRNA 2117) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2117 Gene

Genomics for MIR2117 Gene

Regulatory Elements for MIR2117 Gene

Enhancers for MIR2117 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F043398 1.4 FANTOM5 ENCODE 51.4 -43.3 -43263 6.3 MLX ZFP64 ARID4B SIN3A DMAP1 YBX1 ZNF2 YY1 SLC30A9 FOS MIR2117 RPL29P31 NBR2 AARSD1 HMGN1P29 ETV4 DHX8 ARL4D RNU6-470P
GH17F043395 0.9 Ensembl ENCODE 44.2 -48.2 -48207 1.4 MAFG ZMYM3 ZNF316 GATA2 NFE2L1 NFE2 EMSY NFE2L2 MIR2117 ETV4 ARL4D RNU6-1137P
GH17F043524 1.1 ENCODE 20.5 +83.9 83944 7.7 PKNOX1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 SLC30A9 PAF1 ETV4 MIR2117 NAGLU RPL29P31 RPL27 AOC3 MEOX1 AOC4P RNU6-406P SOST
GH17F043443 1.2 Ensembl ENCODE 15.4 -0.4 -399 1.9 PKNOX1 SIN3A FEZF1 YY1 GLIS2 KLF7 FOS KDM4B YY2 SP5 MIR2117 MIR2117HG GC17M043406
GH17F043465 0.9 ENCODE 20.4 +21.5 21534 0.9 ELF3 MLX ARID4B DMAP1 ZNF48 ZSCAN9 RAD21 RARA YY1 ZNF121 MIR2117 RNU6-1137P ARL4D RNU6-406P ETV4 GC17P043466 GC17P043475
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR2117 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR2117 Gene

43,444,707 bp from pter
43,451,200 bp from pter
6,494 bases
Plus strand

Genomic View for MIR2117 Gene

Genes around MIR2117 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2117 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2117 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2117 Gene

Proteins for MIR2117 Gene

Post-translational modifications for MIR2117 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2117 Gene

Domains & Families for MIR2117 Gene

Gene Families for MIR2117 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2117: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2117 Gene

Function for MIR2117 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2117 Gene

Localization for MIR2117 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2117 Gene

Pathways & Interactions for MIR2117 Gene

SuperPathways for MIR2117 Gene

No Data Available

Interacting Proteins for MIR2117 Gene

Gene Ontology (GO) - Biological Process for MIR2117 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR2117 Gene

Transcripts for MIR2117 Gene

mRNA/cDNA for MIR2117 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2117 Gene

No ASD Table

Relevant External Links for MIR2117 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR2117 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR2117 Gene

mRNA differential expression in normal tissues according to GTEx for MIR2117 Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x18.2) and Skin - Not Sun Exposed (Suprapubic) (x16.7).

NURSA nuclear receptor signaling pathways regulating expression of MIR2117 Gene:

genes like me logo Genes that share expression patterns with MIR2117: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR2117 Gene

Orthologs for MIR2117 Gene

Evolution for MIR2117 Gene

Gene Tree for MIR2117 (if available)
Gene Tree for MIR2117 (if available)

No data available for Orthologs for MIR2117 Gene

Paralogs for MIR2117 Gene

No data available for Paralogs for MIR2117 Gene

Variants for MIR2117 Gene

Sequence variations from dbSNP and Humsavar for MIR2117 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs111925236 -- 43,444,728(+) AATGG(A/T)TCCTG upstream-variant-2KB
rs112991715 -- 43,443,488(+) AACTG(C/T)CCCCC upstream-variant-2KB
rs113224154 -- 43,444,968(+) TTTTG(C/G)TAAGC downstream-variant-500B
rs113227461 -- 43,443,506(+) ACTTC(-/T)TTTTT upstream-variant-2KB
rs114134925 -- 43,444,000(+) CTGGG(C/G)TGGGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2117 Gene

Variant ID Type Subtype PubMed ID
esv2761959 CNV gain 21179565
esv3640625 CNV gain 21293372
nsv1060861 CNV gain 25217958
nsv1065802 CNV gain 25217958
nsv1146669 OTHER inversion 26484159
nsv470588 CNV gain 18288195
nsv833451 CNV loss 17160897
nsv833453 CNV gain+loss 17160897

Relevant External Links for MIR2117 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2117 Gene

Disorders for MIR2117 Gene

Relevant External Links for MIR2117

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR2117 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2117 Gene

Publications for MIR2117 Gene

  1. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. (PMID: 19390579) Wyman S.K. … Tewari M. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR2117 Gene

Sources for MIR2117 Gene

Loading form....