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Aliases for MIR2116 Gene

Subcategory (RNA class) for MIR2116 Gene


Quality Score for this RNA gene is


Aliases for MIR2116 Gene

  • MicroRNA 2116 2 3 5
  • Hsa-Mir-2116 3
  • Mir-2116 3

External Ids for MIR2116 Gene

Previous GeneCards Identifiers for MIR2116 Gene

  • GC00U923641
  • GC15U901171
  • GC15M059463
  • GC15M036285

Summaries for MIR2116 Gene

Entrez Gene Summary for MIR2116 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2116 Gene

MIR2116 (MicroRNA 2116) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2116 Gene

Genomics for MIR2116 Gene

Regulatory Elements for MIR2116 Gene

Enhancers for MIR2116 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F059190 1.4 Ensembl ENCODE 11 -20.6 -20587 2.9 JUN CHD4 BMI1 EED ZNF207 ETV6 FOS CREM MAFK MTA2 LDHAL6B MIR2116 FAM81A
GH15F059516 0.6 Ensembl ENCODE 10.8 -345.8 -345822 1.5 RAD51 USF1 BHLHE40 USF2 RELA MIR2116 MYO1E RNU4-80P GTF2A2 FAM81A GC15M059526 ENSG00000200252
GH15F059492 1.3 Ensembl ENCODE 10.7 -321.8 -321807 0.7 CTCF CEBPG ZNF2 RAD21 TEAD3 RELA SLC30A9 GATAD1 ZNF143 SMC3 FAM81A MIR2116 MYO1E GC15M059526 ENSG00000200252
GH15F059138 0.9 ENCODE 10.5 +32.9 32906 0.2 TBP ATF1 CBX3 ARID4B RAD21 YY1 CHAMP1 GTF3C2 ZNF143 BCLAF1 RPS3AP6 PIGHP1 MIR2116 ENSG00000259732
GH15F059290 1.8 FANTOM5 Ensembl ENCODE 10.4 -127.7 -127733 17.6 HDGF WRNIP1 SIN3A FEZF1 ZNF2 ZNF416 FOS DEK SP3 SP5 MYO1E PIGHP1 RPS3AP6 MIR2116 BNIP2 RNF111 GC15M059271 GC15M059344
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR2116 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR2116 Gene

59,171,183 bp from pter
59,171,262 bp from pter
80 bases
Minus strand

Genomic View for MIR2116 Gene

Genes around MIR2116 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2116 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2116 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2116 Gene

ORGUL Member Location for MIR2116 Gene

ORGUL Member Location for MIR2116 gene

Proteins for MIR2116 Gene

Post-translational modifications for MIR2116 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2116 Gene

Domains & Families for MIR2116 Gene

Gene Families for MIR2116 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2116: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2116 Gene

Function for MIR2116 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2116 Gene

Localization for MIR2116 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2116 Gene

Pathways & Interactions for MIR2116 Gene

SuperPathways for MIR2116 Gene

No Data Available

Interacting Proteins for MIR2116 Gene

Gene Ontology (GO) - Biological Process for MIR2116 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR2116 Gene

Transcripts for MIR2116 Gene

mRNA/cDNA for MIR2116 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2116 Gene

No ASD Table

Relevant External Links for MIR2116 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR2116 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR2116 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2116 Gene:

genes like me logo Genes that share expression patterns with MIR2116: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR2116 Gene

Orthologs for MIR2116 Gene

Evolution for MIR2116 Gene

Gene Tree for MIR2116 (if available)
Gene Tree for MIR2116 (if available)

No data available for Orthologs for MIR2116 Gene

Paralogs for MIR2116 Gene

No data available for Paralogs for MIR2116 Gene

Variants for MIR2116 Gene

Sequence variations from dbSNP and Humsavar for MIR2116 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs10775168 -- 59,170,731(+) CCTGG(C/T)CCTTT intron-variant, downstream-variant-500B
rs112616334 -- 59,171,854(+) TGCTG(A/G)GGCGA intron-variant, upstream-variant-2KB
rs114316226 -- 59,171,859(+) AGGCG(A/C)GAAGG intron-variant, upstream-variant-2KB
rs114995069 -- 59,172,358(+) TCTCA(A/G)AAAAA intron-variant, upstream-variant-2KB
rs115164215 -- 59,171,383(+) CTCCC(C/T)ACTGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2116 Gene

Variant ID Type Subtype PubMed ID
nsv527307 CNV gain 19592680
nsv7266 OTHER inversion 18451855
nsv833025 CNV gain 17160897

Relevant External Links for MIR2116 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2116 Gene

Disorders for MIR2116 Gene

Relevant External Links for MIR2116

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR2116 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2116 Gene

Publications for MIR2116 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. (PMID: 19390579) Wyman S.K. … Tewari M. (PLoS ONE 2009) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR2116 Gene

Sources for MIR2116 Gene

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