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Aliases for MIR2115 Gene

Subcategory (RNA class) for MIR2115 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR2115 Gene

  • MicroRNA 2115 2 3 5
  • Hsa-Mir-2115 3

External Ids for MIR2115 Gene

Previous GeneCards Identifiers for MIR2115 Gene

  • GC00U925565
  • GC03U901348

Summaries for MIR2115 Gene

Entrez Gene Summary for MIR2115 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2115 Gene

MIR2115 (MicroRNA 2115) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2115 Gene

Genomics for MIR2115 Gene

Regulatory Elements for MIR2115 Gene

Enhancers for MIR2115 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F048347 0.6 ENCODE 11.4 -31.2 -31187 0.2 GATA3 REST FOS BCL6 RAD21 RARA FBXW12 MIR2115 NME6 ATRIP CCDC51 TMA7 SPINK8
GH03F048366 0.6 FANTOM5 11.2 -50.2 -50179 0.4 GLIS1 CEBPB ZIC2 ATF2 ZNF589 SPINK8 MIR2115 NME6 PLXNB1 ATRIP ENSG00000244380 TREX1 UCN2 PFKFB4
GH03F048367 0.6 Ensembl 11.2 -50.9 -50942 0.4 CTCF REST ZIC2 ZFP69B POLR2A ZNF692 SMARCA4 GLIS1 SPINK8 MIR2115 NME6 PLXNB1 ATRIP ENSG00000244380 UCN2 PFKFB4 MIR711 COL7A1
GH03F048318 0.4 ENCODE 0.8 -2.5 -2507 0.2 RAD51 ZNF589 FBXW12 CDC25A NDUFB1P1 RNU7-128P MIR2115 SPINK8
GH03F048306 0.4 Ensembl 0.4 +9.4 9359 0.6 ZNF512 PRDM1 ZNF589 SPINK8 FBXW12 PLXNB1 NME6 MIR2115
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR2115 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR2115 Gene

Chromosome:
3
Start:
48,316,360 bp from pter
End:
48,316,459 bp from pter
Size:
100 bases
Orientation:
Minus strand

Genomic View for MIR2115 Gene

Genes around MIR2115 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2115 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2115 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2115 Gene

Proteins for MIR2115 Gene

Post-translational modifications for MIR2115 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2115 Gene

Domains & Families for MIR2115 Gene

Gene Families for MIR2115 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2115: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2115 Gene

Function for MIR2115 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2115 Gene

Localization for MIR2115 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2115 Gene

Pathways & Interactions for MIR2115 Gene

SuperPathways for MIR2115 Gene

No Data Available

Interacting Proteins for MIR2115 Gene

Gene Ontology (GO) - Biological Process for MIR2115 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR2115 Gene

Transcripts for MIR2115 Gene

mRNA/cDNA for MIR2115 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2115 Gene

No ASD Table

Relevant External Links for MIR2115 Gene

GeneLoc Exon Structure for
MIR2115
ECgene alternative splicing isoforms for
MIR2115

Expression for MIR2115 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR2115 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2115 Gene:

MIR2115
genes like me logo Genes that share expression patterns with MIR2115: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR2115 Gene

Orthologs for MIR2115 Gene

Evolution for MIR2115 Gene

ENSEMBL:
Gene Tree for MIR2115 (if available)
TreeFam:
Gene Tree for MIR2115 (if available)

No data available for Orthologs for MIR2115 Gene

Paralogs for MIR2115 Gene

No data available for Paralogs for MIR2115 Gene

Variants for MIR2115 Gene

Sequence variations from dbSNP and Humsavar for MIR2115 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1114321 -- 48,316,496(+) ggcac(A/G)gtggc intron-variant, upstream-variant-2KB
rs112544193 -- 48,317,465(+) CATGC(A/G)CAACA intron-variant, upstream-variant-2KB
rs113598815 -- 48,316,844(+) CCACC(A/G)AACTA intron-variant, upstream-variant-2KB
rs139333408 -- 48,317,213(+) GCTGG(A/G)TGTAG intron-variant, upstream-variant-2KB
rs142451618 -- 48,316,550(+) ACTGC(C/T)TGAGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2115 Gene

Variant ID Type Subtype PubMed ID
nsv834683 CNV gain 17160897

Relevant External Links for MIR2115 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2115

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2115 Gene

Disorders for MIR2115 Gene

Relevant External Links for MIR2115

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR2115

No disorders were found for MIR2115 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2115 Gene

Publications for MIR2115 Gene

  1. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton C.J. … Gunaratne P.H. (PLoS ONE 2010) 3 64
  2. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. (PMID: 19390579) Wyman S.K. … Tewari M. (PLoS ONE 2009) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR2115 Gene

Sources for MIR2115 Gene

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