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Aliases for MIR2114 Gene

Subcategory (RNA class) for MIR2114 Gene


Quality Score for this RNA gene is


Aliases for MIR2114 Gene

  • MicroRNA 2114 2 3 5
  • Hsa-Mir-2114 3

External Ids for MIR2114 Gene

Previous GeneCards Identifiers for MIR2114 Gene

  • GC00U930422
  • GC0XU901437
  • GC0XP149397
  • GC0XP138259

Summaries for MIR2114 Gene

Entrez Gene Summary for MIR2114 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2114 Gene

MIR2114 (MicroRNA 2114) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR2114 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2114 Gene

Genomics for MIR2114 Gene

GeneHancer (GH) Regulatory Elements for MIR2114 Gene

Promoters and enhancers for MIR2114 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI150361 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 11.9 +136.7 136726 5.8 SIN3A GLI4 ZNF2 ZNF48 YY1 ZNF121 GLIS2 ZNF213 KLF7 FOS MAMLD1 MIR2114 GC0XM150545
GH0XI150198 Enhancer 1.4 FANTOM5 Ensembl ENCODE 12.6 -27.9 -27888 3.4 PKNOX1 ATF1 SIN3A IRF4 BRCA1 GLIS2 ELK1 ATF7 FOS RUNX3 MIR2114 MAGEA8 IDS2 LINC00893 MAMLD1 LOC643015 LINC00894
GH0XI150201 Enhancer 1.1 FANTOM5 Ensembl ENCODE 12.6 -25.2 -25208 1.6 CTCF JUNB BATF IRF4 IKZF1 ETV6 RUNX3 SPI1 MIR2114 LINC00893 MAMLD1 LOC643015 LINC00894
GH0XI150205 Enhancer 0.5 ENCODE 13.9 -22.8 -22798 0.1 CTCF RXRA HNF4A RAD21 MIR2114 LOC643015 LINC00894
GH0XI150348 Enhancer 0.3 ENCODE 11.8 +120.6 120588 0.2 SCRT2 GC0XM150346 MIR2114 MAMLD1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR2114 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR2114 Gene

Genomic Locations for MIR2114 Gene
80 bases
Plus strand

Genomic View for MIR2114 Gene

Genes around MIR2114 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2114 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2114 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2114 Gene

Proteins for MIR2114 Gene

Post-translational modifications for MIR2114 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2114 Gene

Domains & Families for MIR2114 Gene

Gene Families for MIR2114 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2114: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2114 Gene

Function for MIR2114 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2114 Gene

Localization for MIR2114 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR2114 Gene

Pathways & Interactions for MIR2114 Gene

SuperPathways for MIR2114 Gene

No Data Available

Interacting Proteins for MIR2114 Gene

Gene Ontology (GO) - Biological Process for MIR2114 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR2114 Gene

Drugs & Compounds for MIR2114 Gene

No Compound Related Data Available

Transcripts for MIR2114 Gene

mRNA/cDNA for MIR2114 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2114 Gene

No ASD Table

Relevant External Links for MIR2114 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR2114 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2114 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR2114 Gene

Orthologs for MIR2114 Gene

Evolution for MIR2114 Gene

Gene Tree for MIR2114 (if available)
Gene Tree for MIR2114 (if available)

No data available for Orthologs for MIR2114 Gene

Paralogs for MIR2114 Gene

No data available for Paralogs for MIR2114 Gene

Variants for MIR2114 Gene

Sequence variations from dbSNP and Humsavar for MIR2114 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1009523319 -- 150,227,499(+) G/A upstream_transcript_variant
rs1010898061 -- 150,227,813(+) C/A/T upstream_transcript_variant
rs1010930459 -- 150,227,543(+) C/T upstream_transcript_variant
rs1013024555 -- 150,226,454(+) G/A upstream_transcript_variant
rs1016422067 -- 150,226,468(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR2114 Gene

Variant ID Type Subtype PubMed ID
nsv525908 CNV gain 19592680

Additional Variant Information for MIR2114 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2114 Gene

Disorders for MIR2114 Gene

Additional Disease Information for MIR2114

No disorders were found for MIR2114 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2114 Gene

Publications for MIR2114 Gene

  1. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 58
  2. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. (PMID: 19390579) Wyman SK … Tewari M (PloS one 2009) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR2114 Gene

Sources for MIR2114 Gene

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