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Aliases for MIR2114 Gene

Subcategory (RNA class) for MIR2114 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR2114 Gene

  • MicroRNA 2114 2 3
  • Hsa-Mir-2114 3

External Ids for MIR2114 Gene

Previous GeneCards Identifiers for MIR2114 Gene

  • GC00U930422
  • GC0XU901437
  • GC0XP149397
  • GC0XP138259

Summaries for MIR2114 Gene

Entrez Gene Summary for MIR2114 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2114 Gene

MIR2114 (MicroRNA 2114) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2114 Gene

Genomics for MIR2114 Gene

Genomic Location for MIR2114 Gene

Start:
150,227,982 bp from pter
End:
150,228,091 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR2114 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR2114 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2114 Gene

No data available for Regulatory Elements for MIR2114 Gene

Proteins for MIR2114 Gene

Post-translational modifications for MIR2114 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2114 Gene

Domains for MIR2114 Gene

Gene Families for MIR2114 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2114: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2114 Gene

Function for MIR2114 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR2114 Gene

Localization for MIR2114 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2114 Gene

Pathways for MIR2114 Gene

SuperPathways for MIR2114 Gene

No Data Available

Interacting Proteins for MIR2114 Gene

Gene Ontology (GO) - Biological Process for MIR2114 Gene

None

No data available for Pathways by source for MIR2114 Gene

Transcripts for MIR2114 Gene

mRNA/cDNA for MIR2114 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR2114

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2114 Gene

No ASD Table

Relevant External Links for MIR2114 Gene

GeneLoc Exon Structure for
MIR2114
ECgene alternative splicing isoforms for
MIR2114

Expression for MIR2114 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR2114 Gene

Orthologs for MIR2114 Gene

Evolution for MIR2114 Gene

ENSEMBL:
Gene Tree for MIR2114 (if available)
TreeFam:
Gene Tree for MIR2114 (if available)

No data available for Orthologs for MIR2114 Gene

Paralogs for MIR2114 Gene

No data available for Paralogs for MIR2114 Gene

Variants for MIR2114 Gene

Sequence variations from dbSNP and Humsavar for MIR2114 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs12383064 -- 150,226,277(+) TTGAC(C/G)AGCCT upstream-variant-2KB
rs12557567 -- 150,226,446(+) AGTAT(C/T)TAGGC upstream-variant-2KB
rs28397601 -- 150,227,113(+) TTAAA(A/C)CAAAT upstream-variant-2KB
rs55903510 -- 150,227,629(+) CACAA(A/G)GGAAG upstream-variant-2KB
rs114424495 -- 150,228,007(+) TGCCT(C/G)CATGC nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR2114 Gene

Variant ID Type Subtype PubMed ID
nsv525908 CNV Gain 19592680

Relevant External Links for MIR2114 Gene

HapMap Linkage Disequilibrium report
MIR2114

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR2114 Gene

Disorders for MIR2114 Gene

No disorders were found for MIR2114 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR2114 Gene

Publications for MIR2114 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. (PMID: 19390579) Wyman S.K. … Tewari M. (PLoS ONE 2009) 3
  3. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton C.J. … Gunaratne P.H. (PLoS ONE 2010) 3

Products for MIR2114 Gene

Sources for MIR2114 Gene

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