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Aliases for MIR2113 Gene

Subcategory (RNA class) for MIR2113 Gene

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Quality Score for this RNA gene is

3

Aliases for MIR2113 Gene

  • MicroRNA 2113 2 3 5
  • Hsa-Mir-2113 3

External Ids for MIR2113 Gene

ORGUL Members for MIR2113 Gene

Previous GeneCards Identifiers for MIR2113 Gene

  • GC00U923189
  • GC06P098472

Summaries for MIR2113 Gene

Entrez Gene Summary for MIR2113 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2113 Gene

MIR2113 (MicroRNA 2113) is an RNA Gene, and is affiliated with the undefined RNA class.

Additional gene information for MIR2113 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2113 Gene

Genomics for MIR2113 Gene

Regulatory Elements for MIR2113 Gene

Enhancers for MIR2113 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H097914 1.5 VISTA 9.8 -109.3 -109306 1 PKNOX1 MAFF ZNF316 MAFG MAFK MIR2113 GC06P097935 GC06P097823
GH06H098056 0.5 VISTA 12.2 +32.6 32640 2 MIR2113 FBXL4 GC06M098179
GH06H098039 1.9 ENCODE dbSUPER 0.4 +16.5 16452 3 CTCF ZNF654 RAD21 ETS1 ZNF316 POLR2A SCRT2 SMC3 POU5F1 RCOR1 FBXL4 MIR2113 GC06M098179
GH06H098043 1.7 VISTA 0.3 +20.1 20127 1 MXI1 POLR2A ZIC2 FBXL4 MIR2113 GC06M098179
GH06H098036 0.7 ENCODE dbSUPER 0.4 +12.0 12029 0 POLR2A POU5F1 FBXL4 MIR2113 GC06M098179
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR2113 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR2113 Gene

Chromosome:
6
Start:
98,024,531 bp from pter
End:
98,024,621 bp from pter
Size:
91 bases
Orientation:
Plus strand

Genomic View for MIR2113 Gene

Genes around MIR2113 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2113 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2113 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2113 Gene

Proteins for MIR2113 Gene

Post-translational modifications for MIR2113 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2113 Gene

Domains & Families for MIR2113 Gene

Gene Families for MIR2113 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2113: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2113 Gene

Function for MIR2113 Gene

Phenotypes From GWAS Catalog for MIR2113 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR2113
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2113 Gene

Localization for MIR2113 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR2113 Gene

Pathways & Interactions for MIR2113 Gene

SuperPathways for MIR2113 Gene

No Data Available

Interacting Proteins for MIR2113 Gene

Gene Ontology (GO) - Biological Process for MIR2113 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR2113 Gene

Drugs & Compounds for MIR2113 Gene

No Compound Related Data Available

Transcripts for MIR2113 Gene

mRNA/cDNA for MIR2113 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR2113
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2113 Gene

No ASD Table

Relevant External Links for MIR2113 Gene

GeneLoc Exon Structure for
MIR2113
ECgene alternative splicing isoforms for
MIR2113

Expression for MIR2113 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2113 Gene:

MIR2113
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR2113 Gene

Orthologs for MIR2113 Gene

Evolution for MIR2113 Gene

ENSEMBL:
Gene Tree for MIR2113 (if available)
TreeFam:
Gene Tree for MIR2113 (if available)

No data available for Orthologs for MIR2113 Gene

Paralogs for MIR2113 Gene

No data available for Paralogs for MIR2113 Gene

Variants for MIR2113 Gene

Sequence variations from dbSNP and Humsavar for MIR2113 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000244125 -- 98,024,747(+) TTAAT(A/C)ATTTT downstream-variant-500B
rs1000485760 -- 98,023,610(+) GGAGT(C/G)AAGGG upstream-variant-2KB
rs1000579929 -- 98,023,171(+) TAATT(A/C/G)CTAAG upstream-variant-2KB
rs1001141968 -- 98,023,692(+) AGTAT(A/C)CTATC upstream-variant-2KB
rs1002127714 -- 98,023,733(+) ATATT(A/G)TCCAC upstream-variant-2KB

Relevant External Links for MIR2113 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2113

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR2113 Gene

Disorders for MIR2113 Gene

Relevant External Links for MIR2113

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR2113

No disorders were found for MIR2113 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2113 Gene

Publications for MIR2113 Gene

  1. Association of AKAP6 and MIR2113 with cognitive performance in a population based sample of older adults. (PMID: 28067462) Andrews SJ … Easteal S (Genes, brain, and behavior 2017) 3 60
  2. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949). (PMID: 25644384) Davies G … Deary IJ (Molecular psychiatry 2015) 3 60
  3. Genome-wide association study reveals two new risk loci for bipolar disorder. (PMID: 24618891) Mühleisen TW … Cichon S (Nature communications 2014) 3 60
  4. Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. (PMID: 23648065) Low SK … Nakamura Y (Cancer science 2013) 3 60
  5. MicroRNA expression patterns and function in endodermal differentiation of human embryonic stem cells. (PMID: 19015728) Tzur G … Galun E (PloS one 2008) 3 60

Products for MIR2113 Gene

Sources for MIR2113 Gene

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