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Aliases for MIR2110 Gene

Subcategory (RNA class) for MIR2110 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR2110 Gene

  • MicroRNA 2110 2 3
  • CCDC186 4 5
  • CTCL Tumor Antigen HD-CL-01/L14-2 4
  • Coiled-Coil Domain Containing 186 5
  • Hsa-Mir-2110 3
  • C10orf118 4
  • Mir-2110 3

External Ids for MIR2110 Gene

Previous GeneCards Identifiers for MIR2110 Gene

  • GC00U923218
  • GC10M115933
  • GC10M114174

Summaries for MIR2110 Gene

Entrez Gene Summary for MIR2110 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2110 Gene

MIR2110 (MicroRNA 2110) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2110 Gene

Genomics for MIR2110 Gene

Regulatory Elements for MIR2110 Gene


Promoters for MIR2110 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR2110 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR2110 Gene

Chromosome:
10
Start:
114,120,862 bp from pter
End:
114,174,220 bp from pter
Size:
53,359 bases
Orientation:
Minus strand

Genomic View for MIR2110 Gene

Genes around MIR2110 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2110 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2110 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2110 Gene

ORGUL Member Location for MIR2110 Gene

ORGUL Member Location for MIR2110 gene

Proteins for MIR2110 Gene

  • Protein details for MIR2110 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z3E2-CC186_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 186
    Protein Accession:
    Q7Z3E2
    Secondary Accessions:
    • Q2M2V6
    • Q3ZB81
    • Q6NS91
    • Q7RTP1
    • Q8N117
    • Q8N3G3
    • Q8N6C2
    • Q9NWA3

    Protein attributes for MIR2110 Gene

    Size:
    898 amino acids
    Molecular mass:
    103687 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH70368.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence starting in position 212.; Evidence={ECO:0000305}; Sequence=AAM44457.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAM44457.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence starting in position 792.; Evidence={ECO:0000305}; Sequence=BAA91480.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC03926.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};

neXtProt entry for MIR2110 Gene

Post-translational modifications for MIR2110 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MIR2110 Gene

No data available for DME Specific Peptides for MIR2110 Gene

Domains & Families for MIR2110 Gene

Gene Families for MIR2110 Gene

Protein Domains for MIR2110 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2110: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2110 Gene

Function for MIR2110 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2110 Gene

Localization for MIR2110 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2110 Gene

Pathways & Interactions for MIR2110 Gene

SuperPathways for MIR2110 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR2110 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR2110 Gene

Drugs & Compounds for MIR2110 Gene

No Compound Related Data Available

Transcripts for MIR2110 Gene

mRNA/cDNA for MIR2110 Gene

(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2110 Gene

No ASD Table

Relevant External Links for MIR2110 Gene

GeneLoc Exon Structure for
MIR2110
ECgene alternative splicing isoforms for
MIR2110

Expression for MIR2110 Gene

mRNA expression in normal human tissues for MIR2110 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2110 Gene:

MIR2110
genes like me logo Genes that share expression patterns with MIR2110: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR2110 Gene

Orthologs for MIR2110 Gene

This gene was present in the common ancestor of animals.

Orthologs for MIR2110 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia C10orf118 35
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia A630007B06Rik 35
  • 82 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C10orf118 35
  • 99 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C10orf118 35
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C10orf118 35
  • 81 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C10orf118 35
  • 89 (a)
OneToOne
chicken
(Gallus gallus)
Aves C10orf118 35
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C10orf118 35
  • 71 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii C12H10orf118 35
  • 59 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG4925 35
  • 27 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea cccp-1 35
  • 24 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 39 (a)
OneToOne
Species where no ortholog for MIR2110 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for MIR2110 Gene

ENSEMBL:
Gene Tree for MIR2110 (if available)
TreeFam:
Gene Tree for MIR2110 (if available)

Paralogs for MIR2110 Gene

No data available for Paralogs for MIR2110 Gene

Variants for MIR2110 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR2110 Gene

Variant ID Type Subtype PubMed ID
nsv7211 OTHER inversion 18451855

Relevant External Links for MIR2110 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2110

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR2110 Gene

Disorders for MIR2110 Gene

Relevant External Links for MIR2110

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR2110

No disorders were found for MIR2110 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2110 Gene

Publications for MIR2110 Gene

  1. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 65
  2. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 65
  4. Identification of novel Epstein-Barr virus microRNA genes from nasopharyngeal carcinomas. (PMID: 19144710) Zhu J.Y. … Meister G. (J. Virol. 2009) 3 65
  5. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PMID: 19413330) Gauci S. … Mohammed S. (Anal. Chem. 2009) 4 65

Products for MIR2110 Gene

Sources for MIR2110 Gene

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