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Aliases for MIR211 Gene

Subcategory (RNA class) for MIR211 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR211 Gene

  • MicroRNA 211 2 3
  • Hsa-Mir-211 3
  • Mir-211 3
  • MIRN211 3

External Ids for MIR211 Gene

Previous HGNC Symbols for MIR211 Gene

  • MIRN211

Previous GeneCards Identifiers for MIR211 Gene

  • GC15M029147
  • GC15M031357

Summaries for MIR211 Gene

Entrez Gene Summary for MIR211 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR211 Gene

MIR211 (MicroRNA 211) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR211 Gene

Genomics for MIR211 Gene

Genomic Location for MIR211 Gene

Chromosome:
15
Start:
31,065,032 bp from pter
End:
31,065,141 bp from pter
Size:
110 bases
Orientation:
Minus strand

Genomic View for MIR211 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR211 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR211 Gene

ORGUL Member Location for MIR211 Gene

ORGUL Member Location for MIR211 gene

No data available for Regulatory Elements for MIR211 Gene

Proteins for MIR211 Gene

Post-translational modifications for MIR211 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR211 Gene

Domains & Families for MIR211 Gene

Gene Families for MIR211 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR211: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR211 Gene

Function for MIR211 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR211 Gene

Localization for MIR211 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR211 Gene

Pathways & Interactions for MIR211 Gene

SuperPathways for MIR211 Gene

No Data Available

Interacting Proteins for MIR211 Gene

Gene Ontology (GO) - Biological Process for MIR211 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR211 Gene

Drugs & Compounds for MIR211 Gene

No Compound Related Data Available

Transcripts for MIR211 Gene

mRNA/cDNA for MIR211 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR211 Gene

No ASD Table

Relevant External Links for MIR211 Gene

GeneLoc Exon Structure for
MIR211
ECgene alternative splicing isoforms for
MIR211

Expression for MIR211 Gene

mRNA expression in normal human tissues for MIR211 Gene

genes like me logo Genes that share expression patterns with MIR211: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR211 Gene

Orthologs for MIR211 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR211 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-211 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-211 36
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-204 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir211 36
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-204 36
  • 64 (a)
OneToMany
oan-mir-204 36
  • 64 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-211 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-204-2 36
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-204a-1 36
  • 80 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CABZ01083725.1 36
  • 77 (a)
OneToMany
dre-mir-204-2 36
  • 56 (a)
OneToMany
Species with no ortholog for MIR211:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR211 Gene

ENSEMBL:
Gene Tree for MIR211 (if available)
TreeFam:
Gene Tree for MIR211 (if available)

Paralogs for MIR211 Gene

No data available for Paralogs for MIR211 Gene

Variants for MIR211 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR211 Gene

Variant ID Type Subtype PubMed ID
nsv903831 CNV Gain 21882294
esv33507 CNV Loss 17666407
nsv903835 CNV Gain 21882294
nsv903836 CNV Gain 21882294
nsv520825 CNV Loss 19592680
nsv456746 CNV Loss 19166990

Relevant External Links for MIR211 Gene

HapMap Linkage Disequilibrium report
MIR211

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR211 Gene

Disorders for MIR211 Gene

Relevant External Links for MIR211

Human Genome Epidemiology (HuGE) Navigator
MIR211
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR211
genes like me logo Genes that share disorders with MIR211: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR211 Gene

Publications for MIR211 Gene

  1. Transcription factor/microRNA axis blocks melanoma invasion program by miR-211 targeting NUAK1. (PMID: 23934065) Bell R.E. … Levy C. (J. Invest. Dermatol. 2014) 67
  2. New target genes of MITF-induced microRNA-211 contribute to melanoma cell invasion. (PMID: 24039954) Margue C. … Kreis S. (PLoS ONE 2013) 67
  3. miR-211 promotes the progression of head and neck carcinomas by targeting TGFI^RII. (PMID: 23726841) Chu T.H. … Chang K.W. (Cancer Lett. 2013) 67
  4. Epigenetic regulation of miRNA-211 by MMP-9 governs glioma cell apoptosis, chemosensitivity and radiosensitivity. (PMID: 23183822) Asuthkar S. … Rao J.S. (Oncotarget 2012) 67
  5. Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors. (PMID: 22223089) Xu Y. … Melton D.W. (Br. J. Cancer 2012) 67

Products for MIR211 Gene

Sources for MIR211 Gene

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