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Aliases for MIR210 Gene

Subcategory (RNA class) for MIR210 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR210 Gene

  • MicroRNA 210 2 3 5
  • Hsa-Mir-210 3
  • Mir-210 3
  • MIRN210 3

External Ids for MIR210 Gene

Previous HGNC Symbols for MIR210 Gene

  • MIRN210

Previous GeneCards Identifiers for MIR210 Gene

  • GC11M000561
  • GC11M000570
  • GC11M000575
  • GC11M000582
  • GC11M000581
  • GC11M000585

Summaries for MIR210 Gene

Entrez Gene Summary for MIR210 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR210 Gene

MIR210 (MicroRNA 210) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR210 include hereditary hemorrhagic telangiectasia. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR210 Gene

Genomics for MIR210 Gene

Regulatory Elements for MIR210 Gene

Promoters for MIR210 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR210 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR210 Gene

Chromosome:
11
Start:
568,089 bp from pter
End:
568,198 bp from pter
Size:
110 bases
Orientation:
Minus strand

Genomic View for MIR210 Gene

Genes around MIR210 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR210 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR210 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR210 Gene

Proteins for MIR210 Gene

Post-translational modifications for MIR210 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR210 Gene

Domains & Families for MIR210 Gene

Gene Families for MIR210 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR210: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR210 Gene

Function for MIR210 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR210 Gene

Localization for MIR210 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR210 Gene

Pathways & Interactions for MIR210 Gene

genes like me logo Genes that share pathways with MIR210: view

Pathways by source for MIR210 Gene

2 BioSystems pathways for MIR210 Gene
1 KEGG pathway for MIR210 Gene

Interacting Proteins for MIR210 Gene

Gene Ontology (GO) - Biological Process for MIR210 Gene

None

No data available for SIGNOR curated interactions for MIR210 Gene

Drugs & Compounds for MIR210 Gene

No Compound Related Data Available

Transcripts for MIR210 Gene

mRNA/cDNA for MIR210 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR210 Gene

No ASD Table

Relevant External Links for MIR210 Gene

GeneLoc Exon Structure for
MIR210
ECgene alternative splicing isoforms for
MIR210

Expression for MIR210 Gene

mRNA expression in normal human tissues for MIR210 Gene

mRNA differential expression in normal tissues according to GTEx for MIR210 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x4.4) and Skin - Sun Exposed (Lower leg) (x4.1).
genes like me logo Genes that share expression patterns with MIR210: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR210 Gene

Orthologs for MIR210 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR210 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-210 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-210 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-210 36
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir210 36
  • 89 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-210 36
  • 99 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 36
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-210 36
  • 72 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-210 36
  • 68 (a)
OneToOne
Species with no ortholog for MIR210:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR210 Gene

ENSEMBL:
Gene Tree for MIR210 (if available)
TreeFam:
Gene Tree for MIR210 (if available)

Paralogs for MIR210 Gene

No data available for Paralogs for MIR210 Gene

Variants for MIR210 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR210 Gene

Variant ID Type Subtype PubMed ID
dgv911n71 CNV Gain 21882294
dgv916n71 CNV Loss 21882294
nsv527327 CNV Loss 19592680
dgv182e199 CNV Deletion 23128226
dgv920n71 CNV Loss 21882294
dgv921n71 CNV Loss 21882294
dgv922n71 CNV Loss 21882294
nsv469923 CNV Loss 18288195
dgv931n71 CNV Loss 21882294
nsv896532 CNV Gain 21882294
essv23843 CNV CNV 17122850
dgv933n71 CNV Loss 21882294
nsv467634 CNV Loss 19166990
nsv896544 CNV Loss 21882294
nsv896545 CNV Loss 21882294
dgv934n71 CNV Loss 21882294
dgv935n71 CNV Loss 21882294
nsv469924 CNV Gain 18288195
dgv936n71 CNV Loss 21882294
dgv938n71 CNV Loss 21882294
dgv939n71 CNV Loss 21882294
nsv467635 CNV Loss 19166990
nsv528415 CNV Loss 19592680
nsv518824 CNV Loss 19592680
nsv896560 CNV Loss 21882294

Relevant External Links for MIR210 Gene

HapMap Linkage Disequilibrium report
MIR210

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR210 Gene

Disorders for MIR210 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR210 Gene - From: GeneCards

Disorder Aliases PubMed IDs
hereditary hemorrhagic telangiectasia
  • osler hemorrhagic telangiectasia syndrome
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR210

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR210
genes like me logo Genes that share disorders with MIR210: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR210 Gene

Publications for MIR210 Gene

  1. MKP-1 is a target of miR-210 and mediate the negative regulation of miR-210 inhibitor on hypoxic hPASMC proliferation. (PMID: 25044272) Jin Y. … Zhao C. (Cell Biol. Int. 2015) 3
  2. Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes. (PMID: 25263437) Cui H. … KrA1ger A. (Oncogene 2015) 3
  3. Acute hypoxia induces upregulation of microRNA-210 expression in glioblastoma spheroids. (PMID: 25586423) Rosenberg T. … Kristensen B.W. (CNS Oncol 2015) 3
  4. HypoxamiRs and cancer: from biology to targeted therapy. (PMID: 24111776) Gee H.E. … Ivan M. (Antioxid. Redox Signal. 2014) 3
  5. Serum miR-210 as a potential biomarker of early clear cell renal cell carcinoma. (PMID: 24212760) Iwamoto H. … Takenaka A. (Int. J. Oncol. 2014) 3

Products for MIR210 Gene

Sources for MIR210 Gene

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