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Aliases for MIR210 Gene

Subcategory (RNA class) for MIR210 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR210 Gene

  • MicroRNA 210 2 3
  • MIRN210 3 6
  • Hsa-Mir-210 3
  • Mir-210 3

External Ids for MIR210 Gene

Previous Symbols for MIR210 Gene

  • MIRN210

Summaries for MIR210 Gene

Entrez Gene Summary for MIR210 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR210 Gene

MIR210 (MicroRNA 210) is a RNA Gene, and belongs to miRNA RNA class. Diseases associated with MIR210 include pulmonary arteriovenous malformation and siderosis. Among its related pathways are MicroRNAs in cancer and SIDS Susceptibility Pathways.

fRNAdb sequence ontologies for MIR210 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR210 Gene

Genomics for MIR210 Gene

Genomic Location for MIR210 Gene

Start:
568,089 bp from pter
End:
568,198 bp from pter
Size:
110 bases
Orientation:
Minus strand

Genomic View for MIR210 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR210 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR210 Gene

No data available for Regulatory Elements for MIR210 Gene

Proteins for MIR210 Gene

Post-translational modifications for MIR210 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR210 Gene

Domains for MIR210 Gene

Gene Families for MIR210 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR210: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR210 Gene

Function for MIR210 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR210 Gene

Localization for MIR210 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR210 Gene

Pathways for MIR210 Gene

genes like me logo Genes that share pathways with MIR210: view

Pathways by source for MIR210 Gene

2 BioSystems pathways for MIR210 Gene
1 KEGG pathway for MIR210 Gene

Interacting Proteins for MIR210 Gene

Gene Ontology (GO) - Biological Process for MIR210 Gene

None

Transcripts for MIR210 Gene

mRNA/cDNA for MIR210 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR210 Gene

No ASD Table

Relevant External Links for MIR210 Gene

GeneLoc Exon Structure for
MIR210
ECgene alternative splicing isoforms for
MIR210

Expression for MIR210 Gene

mRNA expression in normal human tissues for MIR210 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MIR210 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (4.4) and Skin - Sun Exposed (Lower leg) (4.1).
genes like me logo Genes that share expressions with MIR210: view

Orthologs for MIR210 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR210 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-210 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-210 37
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-210 37
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir210 37
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-210 37
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 37
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-210 37
  • 72 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-210 37
  • 68 (a)
OneToOne
Species with no ortholog for MIR210:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR210 Gene

ENSEMBL:
Gene Tree for MIR210 (if available)
TreeFam:
Gene Tree for MIR210 (if available)

Paralogs for MIR210 Gene

No data available for Paralogs for MIR210 Gene

Variants for MIR210 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR210 Gene

Variant ID Type Subtype PubMed ID
dgv911n71 CNV Gain 21882294
dgv916n71 CNV Loss 21882294
nsv527327 CNV Loss 19592680
dgv182e199 CNV Deletion 23128226
dgv920n71 CNV Loss 21882294
dgv921n71 CNV Loss 21882294
dgv922n71 CNV Loss 21882294
nsv469923 CNV Loss 18288195
dgv931n71 CNV Loss 21882294
nsv896532 CNV Gain 21882294
essv23843 CNV CNV 17122850
dgv933n71 CNV Loss 21882294
nsv467634 CNV Loss 19166990
nsv896544 CNV Loss 21882294
nsv896545 CNV Loss 21882294
dgv934n71 CNV Loss 21882294
dgv935n71 CNV Loss 21882294
nsv469924 CNV Gain 18288195
dgv936n71 CNV Loss 21882294
dgv938n71 CNV Loss 21882294
dgv939n71 CNV Loss 21882294
nsv467635 CNV Loss 19166990
nsv528415 CNV Loss 19592680
nsv518824 CNV Loss 19592680
nsv896560 CNV Loss 21882294

Relevant External Links for MIR210 Gene

HapMap Linkage Disequilibrium report
MIR210

No data available for Sequence variations from dbSNP and Humsavar for MIR210 Gene

Disorders for MIR210 Gene

genes like me logo Genes that share disorders with MIR210: view

No data available for UniProtKB/Swiss-Prot for MIR210 Gene

Publications for MIR210 Gene

  1. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 3
  2. Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. (PMID: 15800047) Cai X. … Cullen B.R. (Proc. Natl. Acad. Sci. U.S.A. 2005) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3

Products for MIR210 Gene

Sources for MIR210 Gene

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