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Aliases for MIR20B Gene

Subcategory (RNA class) for MIR20B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR20B Gene

  • MicroRNA 20b 2 3 5
  • Hsa-Mir-20b 3
  • Mir-20b 3
  • MIRN20B 3

External Ids for MIR20B Gene

Previous HGNC Symbols for MIR20B Gene

  • MIRN20B

Previous GeneCards Identifiers for MIR20B Gene

  • GC0XM133153
  • GC0XM133160
  • GC0XM133307
  • GC0XM133312
  • GC0XM133316
  • GC0XM133320
  • GC0XM133325
  • GC0XM133329
  • GC0XM133333
  • GC0XM133337
  • GC0XM133340
  • GC0XM133351
  • GC0XM133375
  • GC0XM134173
  • GC0XM134178

Summaries for MIR20B Gene

Entrez Gene Summary for MIR20B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR20B Gene

MIR20B (MicroRNA 20b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR20B Gene

Genomics for MIR20B Gene

Genomic Location for MIR20B Gene

Chromosome:
X
Start:
134,169,809 bp from pter
End:
134,169,877 bp from pter
Size:
69 bases
Orientation:
Minus strand

Genomic View for MIR20B Gene

Genes around MIR20B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR20B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR20B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR20B Gene

No data available for Regulatory Elements for MIR20B Gene

Proteins for MIR20B Gene

Post-translational modifications for MIR20B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR20B Gene

Domains & Families for MIR20B Gene

Gene Families for MIR20B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR20B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR20B Gene

Function for MIR20B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR20B Gene

Localization for MIR20B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR20B Gene

Pathways & Interactions for MIR20B Gene

SuperPathways for MIR20B Gene

No Data Available

Interacting Proteins for MIR20B Gene

Gene Ontology (GO) - Biological Process for MIR20B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR20B Gene

Drugs & Compounds for MIR20B Gene

No Compound Related Data Available

Transcripts for MIR20B Gene

mRNA/cDNA for MIR20B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR20B Gene

No ASD Table

Relevant External Links for MIR20B Gene

GeneLoc Exon Structure for
MIR20B
ECgene alternative splicing isoforms for
MIR20B

Expression for MIR20B Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR20B Gene

Orthologs for MIR20B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR20B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-20b 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-20b 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-20b 36
  • 61 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir20b 36
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-20b 36
  • 55 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-20b 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-20b 36
  • 66 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-20b 36
  • 55 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-20b 36
  • 54 (a)
OneToOne
Species with no ortholog for MIR20B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR20B Gene

ENSEMBL:
Gene Tree for MIR20B (if available)
TreeFam:
Gene Tree for MIR20B (if available)

Paralogs for MIR20B Gene

No data available for Paralogs for MIR20B Gene

Variants for MIR20B Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR20B Gene

Disorders for MIR20B Gene

Relevant External Links for MIR20B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR20B

No disorders were found for MIR20B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR20B Gene

Publications for MIR20B Gene

  1. MiR-20b, -21, and -130b inhibit PTEN expression resulting in B7-H1 over-expression in advanced colorectal cancer. (PMID: 24468585) Zhu J. … Zhang X. (Hum. Immunol. 2014) 3 67
  2. miR-20b regulates expression of PAR-1 thrombin receptor in melanoma cells. (PMID: 24405508) Saleiban A. … Osman A. (Pigment Cell Melanoma Res 2014) 3
  3. MiRNA 17 family regulates cisplatin-resistant and metastasis by targeting TGFbetaR2 in NSCLC. (PMID: 24722426) Jiang Z. … Zhao J. (PLoS ONE 2014) 3
  4. Underexpression of miR-126 and miR-20b in hereditary and nonhereditary colorectal tumors. (PMID: 24994098) Yamaguchi T. … Miyaki M. (Oncology 2014) 3
  5. Potentially prognostic miRNAs in HPV-associated oropharyngeal carcinoma. (PMID: 23459718) Hui A.B. … Liu F.F. (Clin. Cancer Res. 2013) 3

Products for MIR20B Gene

Sources for MIR20B Gene

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