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Aliases for MIR20A Gene

Subcategory (RNA class) for MIR20A Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR20A Gene

  • MicroRNA 20a 2 3
  • MIRN20A 3 6
  • MicroRNA 20 2
  • Hsa-Mir-20a 3
  • Hsa-Mir-20 3
  • MiRNA20A 3
  • MiR-20 3
  • MIRN20 3
  • MIR20 3

External Ids for MIR20A Gene

ORGUL Members for MIR20A Gene

Previous HGNC Symbols for MIR20A Gene

  • MIRN20
  • MIRN20A

Previous GeneCards Identifiers for MIR20A Gene

  • GC13P090872
  • GC13P090880
  • GC13P092016
  • GC13P092024
  • GC13P092031
  • GC13P092039
  • GC13P092048
  • GC13P092058
  • GC13P092067
  • GC13P092077
  • GC13P092086
  • GC13P092001

Summaries for MIR20A Gene

Entrez Gene Summary for MIR20A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. This miRNA belongs to a polycistronic miRNA cluster that includes six consecutive mature miRNAs that are derived from a single primary transcript. The mature miRNAs of this cluster are often overexpressed in solid cancers. [provided by RefSeq, May 2012]

GeneCards Summary for MIR20A Gene

MIR20A (MicroRNA 20a) is an RNA Gene, and is affiliated with the undefined RNA class. Diseases associated with MIR20A include colorectal adenocarcinoma and mantle cell lymphoma. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR20A Gene

Genomics for MIR20A Gene

Genomic Location for MIR20A Gene

Start:
91,351,065 bp from pter
End:
91,351,135 bp from pter
Size:
71 bases
Orientation:
Plus strand

Genomic View for MIR20A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR20A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR20A Gene

No data available for Regulatory Elements for MIR20A Gene

Proteins for MIR20A Gene

Post-translational modifications for MIR20A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR20A Gene

Domains for MIR20A Gene

Gene Families for MIR20A Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR20A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR20A Gene

Function for MIR20A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR20A Gene

Localization for MIR20A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR20A Gene

Pathways for MIR20A Gene

genes like me logo Genes that share pathways with MIR20A: view

Pathways by source for MIR20A Gene

1 BioSystems pathway for MIR20A Gene
1 KEGG pathway for MIR20A Gene

Interacting Proteins for MIR20A Gene

Gene Ontology (GO) - Biological Process for MIR20A Gene

None

Transcripts for MIR20A Gene

mRNA/cDNA for MIR20A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR20A Gene

No ASD Table

Relevant External Links for MIR20A Gene

GeneLoc Exon Structure for
MIR20A
ECgene alternative splicing isoforms for
MIR20A

Expression for MIR20A Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR20A Gene

Orthologs for MIR20A Gene

Evolution for MIR20A Gene

ENSEMBL:
Gene Tree for MIR20A (if available)
TreeFam:
Gene Tree for MIR20A (if available)

No data available for Orthologs for MIR20A Gene

Paralogs for MIR20A Gene

No data available for Paralogs for MIR20A Gene

Variants for MIR20A Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR20A Gene

Variant ID Type Subtype PubMed ID
nsv832679 CNV Gain 17160897

Relevant External Links for MIR20A Gene

HapMap Linkage Disequilibrium report
MIR20A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR20A Gene

Disorders for MIR20A Gene

MalaCards: The human disease database

MalaCards: The human disease database. (3) Diseases for MIR20A Gene including...

Search for MIR20A Gene in MalaCards »

Relevant External Links for MIR20A

Genetic Association Database (GAD)
MIR20A
Human Genome Epidemiology (HuGE) Navigator
MIR20A
genes like me logo Genes that share disorders with MIR20A: view

No data available for UniProtKB/Swiss-Prot for MIR20A Gene

Publications for MIR20A Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 48
  2. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J. … Zhao H. (Int. J. Cancer 2009) 3 48
  3. Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. (PMID: 19893619) Lei Z. … Huang B. (PLoS ONE 2009) 3
  4. miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging. (PMID: 20089119) Hackl M. … Grillari J. (Aging Cell 2010) 3
  5. Regulating A549 cells growth by ASO inhibiting miRNA expression. (PMID: 20049626) Wang P.Y. … Xie S.Y. (Mol. Cell. Biochem. 2010) 23

Products for MIR20A Gene

Sources for MIR20A Gene

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