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Aliases for MIR208B Gene

Subcategory (RNA class) for MIR208B Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR208B Gene

  • MicroRNA 208b 2 3
  • MIRN208B 3 6
  • Hsa-Mir-208b 3

External Ids for MIR208B Gene

Previous Symbols for MIR208B Gene

  • MIRN208B

Summaries for MIR208B Gene

Entrez Gene Summary for MIR208B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR208B Gene

MIR208B (MicroRNA 208b) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR208B Gene

Genomics for MIR208B Gene

Genomic Location for MIR208B Gene

Start:
23,417,987 bp from pter
End:
23,418,063 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR208B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR208B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR208B Gene

ORGUL Member Location for MIR208B Gene

ORGUL Member Location for MIR208B gene

No data available for Regulatory Elements for MIR208B Gene

Proteins for MIR208B Gene

Post-translational modifications for MIR208B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR208B Gene

Domains for MIR208B Gene

Gene Families for MIR208B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR208B: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR208B Gene

Function for MIR208B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR208B Gene

Localization for MIR208B Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR208B Gene

Pathways for MIR208B Gene

SuperPathways for MIR208B Gene

No Data Available

Interacting Proteins for MIR208B Gene

Gene Ontology (GO) - Biological Process for MIR208B Gene

None

No data available for Pathways by source for MIR208B Gene

Transcripts for MIR208B Gene

mRNA/cDNA for MIR208B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR208B Gene

No ASD Table

Relevant External Links for MIR208B Gene

GeneLoc Exon Structure for
MIR208B
ECgene alternative splicing isoforms for
MIR208B

Expression for MIR208B Gene

mRNA expression in normal human tissues for MIR208B Gene

genes like me logo Genes that share expressions with MIR208B: view

Orthologs for MIR208B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR208B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-208b 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-208b 37
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-208b 37
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir208b 37
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-208b 37
  • 91 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-736 37
  • 70 (a)
OneToOne
Species with no ortholog for MIR208B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR208B Gene

ENSEMBL:
Gene Tree for MIR208B (if available)
TreeFam:
Gene Tree for MIR208B (if available)

Paralogs for MIR208B Gene

No data available for Paralogs for MIR208B Gene

Variants for MIR208B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR208B Gene

Variant ID Type Subtype PubMed ID
nsv901493 CNV Loss 21882294
esv2748480 CNV Deletion 23290073
nsv470623 CNV Gain 18288195
nsv456166 CNV Gain 19166990

Relevant External Links for MIR208B Gene

HapMap Linkage Disequilibrium report
MIR208B

No data available for Sequence variations from dbSNP and Humsavar for MIR208B Gene

Disorders for MIR208B Gene

No disorders were found for MIR208B Gene.

No data available for UniProtKB/Swiss-Prot for MIR208B Gene

Publications for MIR208B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E. … Cuppen E. (Genome Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Circulating MicroRNA-208b and MicroRNA-499 reflect myocardial damage in cardiovascular disease. (PMID: 20921333) Corsten M.F. … Schroen B. (Circ Cardiovasc Genet 2010) 3
  5. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3

Products for MIR208B Gene

Sources for MIR208B Gene

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