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Aliases for MIR208B Gene

Subcategory (RNA class) for MIR208B Gene


Quality Score for this RNA gene is


Aliases for MIR208B Gene

  • MicroRNA 208b 2 3
  • Hsa-Mir-208b 3
  • Mir-208b 3
  • MIRN208B 3

External Ids for MIR208B Gene

Previous HGNC Symbols for MIR208B Gene

  • MIRN208B

Previous GeneCards Identifiers for MIR208B Gene

  • GC14M022959
  • GC14M023887

Summaries for MIR208B Gene

Entrez Gene Summary for MIR208B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR208B Gene

MIR208B (MicroRNA 208b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR208B Gene

Genomics for MIR208B Gene

Genomic Location for MIR208B Gene

23,417,987 bp from pter
23,418,063 bp from pter
77 bases
Minus strand

Genomic View for MIR208B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR208B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR208B Gene

ORGUL Member Location for MIR208B Gene

ORGUL Member Location for MIR208B gene

No data available for Regulatory Elements for MIR208B Gene

Proteins for MIR208B Gene

Post-translational modifications for MIR208B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR208B Gene

Domains & Families for MIR208B Gene

Gene Families for MIR208B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR208B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR208B Gene

Function for MIR208B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR208B Gene

Localization for MIR208B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR208B Gene

Pathways & Interactions for MIR208B Gene

SuperPathways for MIR208B Gene

No Data Available

Interacting Proteins for MIR208B Gene

Gene Ontology (GO) - Biological Process for MIR208B Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR208B Gene

Drugs & Compounds for MIR208B Gene

No Compound Related Data Available

Transcripts for MIR208B Gene

mRNA/cDNA for MIR208B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR208B Gene

No ASD Table

Relevant External Links for MIR208B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR208B Gene

mRNA expression in normal human tissues for MIR208B Gene

genes like me logo Genes that share expression patterns with MIR208B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR208B Gene

Orthologs for MIR208B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR208B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-208b 36
  • 91 (a)
(Canis familiaris)
Mammalia cfa-mir-208b 36
  • 95 (a)
(Monodelphis domestica)
Mammalia mdo-mir-208b 36
  • 91 (a)
(Mus musculus)
Mammalia Mir208b 36
  • 95 (a)
(Pan troglodytes)
Mammalia ptr-mir-208b 36
  • 100 (a)
(Danio rerio)
Actinopterygii dre-mir-736 36
  • 70 (a)
Species with no ortholog for MIR208B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR208B Gene

Gene Tree for MIR208B (if available)
Gene Tree for MIR208B (if available)

Paralogs for MIR208B Gene

No data available for Paralogs for MIR208B Gene

Variants for MIR208B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR208B Gene

Variant ID Type Subtype PubMed ID
nsv901493 CNV Loss 21882294
esv2748480 CNV Deletion 23290073
nsv470623 CNV Gain 18288195
nsv456166 CNV Gain 19166990

Relevant External Links for MIR208B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR208B Gene

Disorders for MIR208B Gene

Relevant External Links for MIR208B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR208B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR208B Gene

Publications for MIR208B Gene

  1. The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs. (PMID: 24241692) McFarland A.P. … Savan R. (Nat. Immunol. 2014) 67
  2. Circulating cardio-enriched microRNAs are associated with long-term prognosis following myocardial infarction. (PMID: 23448306) GidlAPf O. … Erlinge D. (BMC Cardiovasc Disord 2013) 67
  3. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 67
  4. Association between circulating microRNAs, cardiovascular risk factors and outcome in patients with acute myocardial infarction. (PMID: 23871635) Goretti E. … Devaux Y. (Int. J. Cardiol. 2013) 67
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 67

Products for MIR208B Gene

Sources for MIR208B Gene

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