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Aliases for MIR2054 Gene

Subcategory (RNA class) for MIR2054 Gene

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Quality Score for this RNA gene is

3

Aliases for MIR2054 Gene

  • MicroRNA 2054 2 3 5
  • Hsa-Mir-2054 3

External Ids for MIR2054 Gene

ORGUL Members for MIR2054 Gene

Previous GeneCards Identifiers for MIR2054 Gene

  • GC00U923223
  • GC04P126428

Summaries for MIR2054 Gene

Entrez Gene Summary for MIR2054 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2054 Gene

MIR2054 (MicroRNA 2054) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2054 Gene

Genomics for MIR2054 Gene

Regulatory Elements for MIR2054 Gene

Enhancers for MIR2054 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04G125518 1.2 VISTA ENCODE 0.4 +12.6 12569 2.3 PKNOX1 TAF1 JUN ZNF384 RAD21 YY1 FOXA1 JUND GATA2 HNF4A MIR2054 ENSG00000250149
GH04G125573 0.7 ENCODE 0.2 +66.6 66634 1.6 PKNOX1 DPF2 REST TCF12 ARID1B ZNF316 GATA2 SMARCA4 IKZF1 PBX2 MIR2054 ENSG00000250149
GH04G125433 0.5 ENCODE 0.2 -73.3 -73307 1.1 GATA2 ATF3 CEBPB CEBPG FOS GC04P125393 MIR2054
GH04G125638 0.9 Ensembl ENCODE 0.1 +132.2 132183 2.0 MAX MAFG CHD7 RAD21 ZNF316 JUND GATA3 HDAC2 HNF4A FOS ENSG00000250149 MIR2054
GH04G125619 0.4 ENCODE 0.1 +113.0 113049 0.9 ZNF316 ENSG00000250149 MIR2054
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR2054 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR2054 Gene

Chromosome:
4
Start:
125,507,259 bp from pter
End:
125,507,307 bp from pter
Size:
49 bases
Orientation:
Plus strand

Genomic View for MIR2054 Gene

Genes around MIR2054 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2054 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2054 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2054 Gene

Proteins for MIR2054 Gene

Post-translational modifications for MIR2054 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2054 Gene

Domains & Families for MIR2054 Gene

Gene Families for MIR2054 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2054: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2054 Gene

Function for MIR2054 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2054 Gene

Localization for MIR2054 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2054 Gene

Pathways & Interactions for MIR2054 Gene

SuperPathways for MIR2054 Gene

No Data Available

Interacting Proteins for MIR2054 Gene

Gene Ontology (GO) - Biological Process for MIR2054 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR2054 Gene

Transcripts for MIR2054 Gene

mRNA/cDNA for MIR2054 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2054 Gene

No ASD Table

Relevant External Links for MIR2054 Gene

GeneLoc Exon Structure for
MIR2054
ECgene alternative splicing isoforms for
MIR2054

Expression for MIR2054 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2054 Gene:

MIR2054
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR2054 Gene

Orthologs for MIR2054 Gene

Evolution for MIR2054 Gene

ENSEMBL:
Gene Tree for MIR2054 (if available)
TreeFam:
Gene Tree for MIR2054 (if available)

No data available for Orthologs for MIR2054 Gene

Paralogs for MIR2054 Gene

No data available for Paralogs for MIR2054 Gene

Variants for MIR2054 Gene

Sequence variations from dbSNP and Humsavar for MIR2054 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1001795735 -- 125,507,692(+) ATATA(A/G)ACATA downstream-variant-500B
rs1003162531 -- 125,506,113(+) ACTTA(C/T)TTATA upstream-variant-2KB
rs1004258301 -- 125,505,886(+) TTCAT(A/G)GTTGG upstream-variant-2KB
rs1004643291 -- 125,507,569(+) TGAGA(C/T)ATAAA downstream-variant-500B
rs1007037703 -- 125,505,542(+) TTTCT(C/T)TCTCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2054 Gene

Variant ID Type Subtype PubMed ID
nsv1010746 CNV gain 25217958

Relevant External Links for MIR2054 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2054

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2054 Gene

Disorders for MIR2054 Gene

Relevant External Links for MIR2054

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR2054

No disorders were found for MIR2054 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2054 Gene

Publications for MIR2054 Gene

  1. A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. (PMID: 19734545) Need A.C. … Goldstein D.B. (Hum. Mol. Genet. 2009) 3 64
  2. Prediction of human miRNAs using tissue-selective motifs in 3' UTRs. (PMID: 18952845) Chang Y.M. … Shih A.C. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR2054 Gene

Sources for MIR2054 Gene

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