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Aliases for MIR2053 Gene

Subcategory (RNA class) for MIR2053 Gene


Quality Score for this RNA gene is


Aliases for MIR2053 Gene

  • MicroRNA 2053 2 3 5
  • Hsa-Mir-2053 3

External Ids for MIR2053 Gene

ORGUL Members for MIR2053 Gene

Previous GeneCards Identifiers for MIR2053 Gene

  • GC00U923212
  • GC08P113655

Summaries for MIR2053 Gene

Entrez Gene Summary for MIR2053 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2053 Gene

MIR2053 (MicroRNA 2053) is an RNA Gene, and is affiliated with the undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2053 Gene

Genomics for MIR2053 Gene

Regulatory Elements for MIR2053 Gene

Enhancers for MIR2053 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F112673 0.5 Ensembl ENCODE 11.3 +30.6 30648 2.0 ZFP64 ZNF140 CBX5 EED ZNF207 ETV6 ZNF433 CREM MAFK TCF7L2 MIR2053 GC08P112947
GH08F112772 0.4 ENCODE 0.1 +129.2 129199 0.8 MAX CSMD3 MIR2053 GC08P112947
GH08F112806 0.7 ENCODE 0.1 +163.3 163271 0.7 CTCF SMC3 ZNF652 RAD21 CSMD3 GC08P112947 MIR2053
GH08F112881 0.6 ENCODE 0.1 +238.8 238764 1.2 MAX NFE2 MAFK GC08P112947 MIR2053
GH08F112887 0.2 ENCODE 0.1 +244.9 244908 2.0 FOXP2 TCF7L2 GC08P112947 MIR2053
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR2053 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR2053 Gene

112,643,493 bp from pter
112,643,583 bp from pter
91 bases
Plus strand

Genomic View for MIR2053 Gene

Genes around MIR2053 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2053 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2053 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2053 Gene

Proteins for MIR2053 Gene

Post-translational modifications for MIR2053 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2053 Gene

Domains & Families for MIR2053 Gene

Gene Families for MIR2053 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2053: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2053 Gene

Function for MIR2053 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2053 Gene

Localization for MIR2053 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR2053 Gene

Pathways & Interactions for MIR2053 Gene

SuperPathways for MIR2053 Gene

No Data Available

Interacting Proteins for MIR2053 Gene

Gene Ontology (GO) - Biological Process for MIR2053 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR2053 Gene

Transcripts for MIR2053 Gene

mRNA/cDNA for MIR2053 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2053 Gene

No ASD Table

Relevant External Links for MIR2053 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR2053 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2053 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR2053 Gene

Orthologs for MIR2053 Gene

Evolution for MIR2053 Gene

Gene Tree for MIR2053 (if available)
Gene Tree for MIR2053 (if available)

No data available for Orthologs for MIR2053 Gene

Paralogs for MIR2053 Gene

No data available for Paralogs for MIR2053 Gene

Variants for MIR2053 Gene

Sequence variations from dbSNP and Humsavar for MIR2053 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10505168 -- 112,643,523(-) TGCAA(A/G)TGTTA intron-variant, nc-transcript-variant
rs10505169 -- 112,643,367(-) TAATA(C/T)AGTCT intron-variant, upstream-variant-2KB
rs111639596 -- 112,641,580(+) ACCTG(C/T)AATCC intron-variant, upstream-variant-2KB
rs111999114 -- 112,642,341(+) ACAAC(A/G)TGTTT intron-variant, upstream-variant-2KB
rs112584207 -- 112,643,414(+) TGTAA(-/C)ATTTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR2053 Gene

Variant ID Type Subtype PubMed ID
nsv831427 CNV loss 17160897

Relevant External Links for MIR2053 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2053 Gene

Disorders for MIR2053 Gene

Relevant External Links for MIR2053

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR2053 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2053 Gene

Publications for MIR2053 Gene

  1. Prediction of human miRNAs using tissue-selective motifs in 3' UTRs. (PMID: 18952845) Chang Y.M. … Shih A.C. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR2053 Gene

Sources for MIR2053 Gene

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