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Aliases for MIR205 Gene

Subcategory (RNA class) for MIR205 Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR205 Gene

  • MicroRNA 205 2 3
  • MIRN205 3 6
  • Hsa-Mir-205 3

External Ids for MIR205 Gene

ORGUL Members for MIR205 Gene

Previous HGNC Symbols for MIR205 Gene

  • MIRN205

Previous GeneCards Identifiers for MIR205 Gene

  • GC01P207673
  • GC01P209605

Summaries for MIR205 Gene

Entrez Gene Summary for MIR205 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR205 Gene

MIR205 (MicroRNA 205) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR205 Gene

Genomics for MIR205 Gene

Genomic Location for MIR205 Gene

Start:
209,432,133 bp from pter
End:
209,432,242 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR205 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR205 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR205 Gene

No data available for Regulatory Elements for MIR205 Gene

Proteins for MIR205 Gene

Post-translational modifications for MIR205 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR205 Gene

Domains for MIR205 Gene

Gene Families for MIR205 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR205: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR205 Gene

Function for MIR205 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR205 Gene

Localization for MIR205 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR205 Gene

Pathways for MIR205 Gene

SuperPathways for MIR205 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR205: view

Pathways by source for MIR205 Gene

1 KEGG pathway for MIR205 Gene

Interacting Proteins for MIR205 Gene

Gene Ontology (GO) - Biological Process for MIR205 Gene

None

Transcripts for MIR205 Gene

mRNA/cDNA for MIR205 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR205 Gene

No ASD Table

Relevant External Links for MIR205 Gene

GeneLoc Exon Structure for
MIR205
ECgene alternative splicing isoforms for
MIR205

Expression for MIR205 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR205 Gene

Orthologs for MIR205 Gene

Evolution for MIR205 Gene

ENSEMBL:
Gene Tree for MIR205 (if available)
TreeFam:
Gene Tree for MIR205 (if available)

No data available for Orthologs for MIR205 Gene

Paralogs for MIR205 Gene

No data available for Paralogs for MIR205 Gene

Variants for MIR205 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR205 Gene

Variant ID Type Subtype PubMed ID
nsv873138 CNV Gain 21882294

Relevant External Links for MIR205 Gene

HapMap Linkage Disequilibrium report
MIR205

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR205 Gene

Disorders for MIR205 Gene

Relevant External Links for MIR205

Genetic Association Database (GAD)
MIR205
Human Genome Epidemiology (HuGE) Navigator
MIR205
genes like me logo Genes that share disorders with MIR205: view

No data available for UniProtKB/Swiss-Prot for MIR205 Gene

Publications for MIR205 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 48
  2. Expression of microRNAs in squamous cell carcinoma of human head and neck and the esophagus: miR-205 and miR-21 are specific markers for HNSCC and ESCC. (PMID: 20428818) Kimura S. … Itoh H. (Oncol. Rep. 2010) 3
  3. The ups and downs of miR-205: identifying the roles of miR-205 in mammary gland development and breast cancer. (PMID: 20436283) Greene S.B. … Rosen J.M. (RNA Biol 2010) 3
  4. MicroRNA-205 promotes keratinocyte migration via the lipid phosphatase SHIP2. (PMID: 20530248) Yu J. … Lavker R.M. (FASEB J. 2010) 3
  5. MicroRNAs and esophageal squamous cell carcinoma. (PMID: 20588024) Matsushima K. … Nakao K. (Digestion 2010) 3

Products for MIR205 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR205
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR205
    • Block miRNA regulation of MIR205 using miScript Target Protectors

    Sources for MIR205 Gene

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