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Aliases for MIR205 Gene

Subcategory (RNA class) for MIR205 Gene

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Quality Score for this RNA gene is

3

Aliases for MIR205 Gene

  • MicroRNA 205 2 3 5
  • Hsa-Mir-205 3
  • Mir-205 3
  • MIRN205 3

External Ids for MIR205 Gene

ORGUL Members for MIR205 Gene

Previous HGNC Symbols for MIR205 Gene

  • MIRN205

Previous GeneCards Identifiers for MIR205 Gene

  • GC01P207673
  • GC01P209605

Summaries for MIR205 Gene

Entrez Gene Summary for MIR205 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR205 Gene

MIR205 (MicroRNA 205) is an RNA Gene, and is affiliated with the undefined RNA class. Diseases associated with MIR205 include hereditary hemorrhagic telangiectasia. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR205 Gene

Genomics for MIR205 Gene

Regulatory Elements for MIR205 Gene

Promoters for MIR205 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR205 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR205 Gene

Chromosome:
1
Start:
209,432,133 bp from pter
End:
209,432,242 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR205 Gene

Genes around MIR205 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR205 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR205 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR205 Gene

Proteins for MIR205 Gene

Post-translational modifications for MIR205 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR205 Gene

Domains & Families for MIR205 Gene

Gene Families for MIR205 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR205: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR205 Gene

Function for MIR205 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR205 Gene

Localization for MIR205 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR205 Gene

Pathways & Interactions for MIR205 Gene

SuperPathways for MIR205 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR205: view

Pathways by source for MIR205 Gene

1 KEGG pathway for MIR205 Gene

Interacting Proteins for MIR205 Gene

Gene Ontology (GO) - Biological Process for MIR205 Gene

None

No data available for SIGNOR curated interactions for MIR205 Gene

Drugs & Compounds for MIR205 Gene

No Compound Related Data Available

Transcripts for MIR205 Gene

mRNA/cDNA for MIR205 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR205 Gene

No ASD Table

Relevant External Links for MIR205 Gene

GeneLoc Exon Structure for
MIR205
ECgene alternative splicing isoforms for
MIR205

Expression for MIR205 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR205 Gene

Orthologs for MIR205 Gene

Evolution for MIR205 Gene

ENSEMBL:
Gene Tree for MIR205 (if available)
TreeFam:
Gene Tree for MIR205 (if available)

No data available for Orthologs for MIR205 Gene

Paralogs for MIR205 Gene

No data available for Paralogs for MIR205 Gene

Variants for MIR205 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR205 Gene

Variant ID Type Subtype PubMed ID
nsv873138 CNV Gain 21882294

Relevant External Links for MIR205 Gene

HapMap Linkage Disequilibrium report
MIR205

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR205 Gene

Disorders for MIR205 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR205 Gene - From: GeneCards

Disorder Aliases PubMed IDs
hereditary hemorrhagic telangiectasia
  • osler hemorrhagic telangiectasia syndrome
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR205

Genetic Association Database (GAD)
MIR205
Human Genome Epidemiology (HuGE) Navigator
MIR205
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR205
genes like me logo Genes that share disorders with MIR205: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR205 Gene

Publications for MIR205 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 48 67
  2. Accuracy of microRNAs as markers for the detection of neck lymph node metastases in patients with head and neck squamous cell carcinoma. (PMID: 25956054) de Carvalho A.C. … Vettore A.L. (BMC Med 2015) 3
  3. Prognostic role of microRNA-205 in multiple human malignant neoplasms: a meta-analysis of 17 studies. (PMID: 25613953) Zhang J.Y. … Yang J. (BMJ Open 2015) 3
  4. The role of miR-205 in the VEGF-mediated promotion of human ovarian cancer cell invasion. (PMID: 25597268) Li J. … Wu X. (Gynecol. Oncol. 2015) 3
  5. Circulating miR-19a and miR-205 in serum may predict the sensitivity of luminal A subtype of breast cancer patients to neoadjuvant chemotherapy with epirubicin plus paclitaxel. (PMID: 25137071) Li Q. … Xu B. (PLoS ONE 2014) 3

Products for MIR205 Gene

Sources for MIR205 Gene

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