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Aliases for MIR204 Gene

Subcategory (RNA class) for MIR204 Gene

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Quality Score for this RNA gene is

8.2

Aliases for MIR204 Gene

  • MicroRNA 204 2 3
  • MIRN204 3 6
  • Hsa-Mir-204 3
  • MiRNA204 3

External Ids for MIR204 Gene

Previous Symbols for MIR204 Gene

  • MIRN204

Summaries for MIR204 Gene

Entrez Gene Summary for MIR204 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR204 Gene

MIR204 (MicroRNA 204) is a RNA Gene, and belongs to undefined RNA class.

fRNAdb sequence ontologies for MIR204 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR204

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR204 Gene

Genomics for MIR204 Gene

Genomic Location for MIR204 Gene

Start:
70,809,975 bp from pter
End:
70,810,084 bp from pter
Size:
110 bases
Orientation:
Minus strand

Genomic View for MIR204 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR204 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR204 Gene

ORGUL Member Location for MIR204 Gene

ORGUL Member Location for MIR204 gene

No data available for Regulatory Elements for MIR204 Gene

Proteins for MIR204 Gene

Post-translational modifications for MIR204 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR204 Gene

Domains for MIR204 Gene

Gene Families for MIR204 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR204: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR204 Gene

Function for MIR204 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR204 Gene

Localization for MIR204 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR204 Gene

Pathways for MIR204 Gene

SuperPathways for MIR204 Gene

No Data Available

Interacting Proteins for MIR204 Gene

Gene Ontology (GO) - Biological Process for MIR204 Gene

None

No data available for Pathways by source for MIR204 Gene

Transcripts for MIR204 Gene

fRNAdb Secondary structures for MIR204 Gene

  • FR370744

mRNA/cDNA for MIR204 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR204 Gene

No ASD Table

Relevant External Links for MIR204 Gene

GeneLoc Exon Structure for
MIR204
ECgene alternative splicing isoforms for
MIR204

Expression for MIR204 Gene

mRNA expression in normal human tissues for MIR204 Gene

genes like me logo Genes that share expressions with MIR204: view

Orthologs for MIR204 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR204 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-204 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-204 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-204 37
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir204 37
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 88 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-204-1 37
  • 88 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-204a-2 37
  • 90 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-204-1 37
  • 80 (a)
OneToOne
Species with no ortholog for MIR204:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR204 Gene

ENSEMBL:
Gene Tree for MIR204 (if available)
TreeFam:
Gene Tree for MIR204 (if available)

Paralogs for MIR204 Gene

No data available for Paralogs for MIR204 Gene

Variants for MIR204 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR204 Gene

Variant ID Type Subtype PubMed ID
nsv893440 CNV Gain 21882294

Relevant External Links for MIR204 Gene

HapMap Linkage Disequilibrium report
MIR204

No data available for Sequence variations from dbSNP and Humsavar for MIR204 Gene

Disorders for MIR204 Gene

Relevant External Links for MIR204

Human Genome Epidemiology (HuGE) Navigator
MIR204
genes like me logo Genes that share disorders with MIR204: view

No data available for UniProtKB/Swiss-Prot for MIR204 Gene

Publications for MIR204 Gene

  1. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. MicroRNA-204/211 alters epithelial physiology. (PMID: 20056717) Wang F.E. … Miller S.S. (FASEB J. 2010) 3
  5. Genetic polymorphisms in the precursor MicroRNA flanking region and non-small cell lung cancer survival. (PMID: 20889907) Hu Z. … Shen H. (Am. J. Respir. Crit. Care Med. 2011) 3

Products for MIR204 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR204
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR204
    • Block miRNA regulation of MIR204 using miScript Target Protectors

    Sources for MIR204 Gene

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