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Aliases for MIR203B Gene

Subcategory (RNA class) for MIR203B Gene

miRNA

Quality Score for this RNA gene is

7

Aliases for MIR203B Gene

  • MicroRNA 203b 2 3
  • MicroRNA 3545 2 3
  • Hsa-Mir-203b 3
  • Hsa-Mir-3545 3
  • MIR3545 3

External Ids for MIR203B Gene

Previous HGNC Symbols for MIR203B Gene

  • MIR3545

Previous GeneCards Identifiers for MIR203B Gene

  • GC14M104588

Summaries for MIR203B Gene

Entrez Gene Summary for MIR203B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR203B Gene

MIR203B (MicroRNA 203b) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR203B Gene

Genomics for MIR203B Gene

Genomic Location for MIR203B Gene

Start:
104,117,418 bp from pter
End:
104,117,503 bp from pter
Size:
86 bases
Orientation:
Minus strand

Genomic View for MIR203B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR203B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR203B Gene

ORGUL Member Location for MIR203B Gene

ORGUL Member Location for MIR203B gene

No data available for Regulatory Elements for MIR203B Gene

Proteins for MIR203B Gene

Post-translational modifications for MIR203B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR203B Gene

Domains for MIR203B Gene

Gene Families for MIR203B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR203B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR203B Gene

Function for MIR203B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR203B Gene

Localization for MIR203B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR203B Gene

Pathways for MIR203B Gene

SuperPathways for MIR203B Gene

Superpath Contained pathways
1 miRNAs involved in DDR
genes like me logo Genes that share pathways with MIR203B: view

Pathways by source for MIR203B Gene

1 BioSystems pathway for MIR203B Gene

Interacting Proteins for MIR203B Gene

Gene Ontology (GO) - Biological Process for MIR203B Gene

None

Transcripts for MIR203B Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR203B Gene

No ASD Table

Relevant External Links for MIR203B Gene

GeneLoc Exon Structure for
MIR203B
ECgene alternative splicing isoforms for
MIR203B

No data available for mRNA/cDNA for MIR203B Gene

Expression for MIR203B Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR203B Gene

Orthologs for MIR203B Gene

No data available for Orthologs and Evolution for MIR203B Gene

Paralogs for MIR203B Gene

No data available for Paralogs for MIR203B Gene

Variants for MIR203B Gene

Sequence variations from dbSNP and Humsavar for MIR203B Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs1771006 -- 104,118,777(-) CTACA(A/G)GGGGC upstream-variant-2KB
rs1771007 -- 104,118,658(-) TGGCC(A/G)CAATG upstream-variant-2KB
rs11623299 -- 104,119,390(+) TGTAG(A/G)CTGGC upstream-variant-2KB
rs28490059 -- 104,119,233(+) TCCCT(C/T)GGGTT upstream-variant-2KB
rs59412558 -- 104,118,844(+) AGCAG(C/T)CCCGT upstream-variant-2KB

Relevant External Links for MIR203B Gene

HapMap Linkage Disequilibrium report
MIR203B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR203B Gene

Disorders for MIR203B Gene

No disorders were found for MIR203B Gene.

No data available for UniProtKB/Swiss-Prot for MIR203B Gene

Publications for MIR203B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3
  3. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce C.E. … Bowcock A.M. (Hum. Mol. Genet. 2011) 3

Products for MIR203B Gene

Sources for MIR203B Gene

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