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Aliases for MIR203A Gene

Subcategory (RNA class) for MIR203A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR203A Gene

  • MicroRNA 203a 2 3
  • MicroRNA 203 2 3
  • MIRN203 3 6
  • MIR203 3 6
  • Hsa-Mir-203a 3
  • Hsa-Mir-203 3
  • MiRNA203 3
  • MiR-203 3

External Ids for MIR203A Gene

ORGUL Members for MIR203A Gene

Previous Symbols for MIR203A Gene

  • MIRN203
  • MIR203

Summaries for MIR203A Gene

Entrez Gene Summary for MIR203A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR203A Gene

MIR203A (MicroRNA 203a) is a RNA Gene, and belongs to miRNA RNA class. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR203A Gene

Genomics for MIR203A Gene

Genomic Location for MIR203A Gene

Start:
104,117,405 bp from pter
End:
104,117,514 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR203A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR203A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR203A Gene

No data available for Regulatory Elements for MIR203A Gene

Proteins for MIR203A Gene

Post-translational modifications for MIR203A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR203A Gene

Domains for MIR203A Gene

Gene Families for MIR203A Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR203A: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR203A Gene

Function for MIR203A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR203A Gene

Localization for MIR203A Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR203A Gene

Pathways for MIR203A Gene

genes like me logo Genes that share pathways with MIR203A: view

Pathways by source for MIR203A Gene

1 BioSystems pathway for MIR203A Gene
1 KEGG pathway for MIR203A Gene

Interacting Proteins for MIR203A Gene

Gene Ontology (GO) - Biological Process for MIR203A Gene

None

Transcripts for MIR203A Gene

mRNA/cDNA for MIR203A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR203A Gene

No ASD Table

Relevant External Links for MIR203A Gene

GeneLoc Exon Structure for
MIR203A
ECgene alternative splicing isoforms for
MIR203A

Expression for MIR203A Gene

mRNA expression in normal human tissues for MIR203A Gene

mRNA differential expression in normal tissues according to GTEx for MIR203A Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (17.6), Skin - Not Sun Exposed (Suprapubic) (17.1), and Esophagus - Mucosa (11.8).
genes like me logo Genes that share expressions with MIR203A: view

Orthologs for MIR203A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR203A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-203 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-203 37
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir203 37
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-203 37
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 73 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-203 37
  • 77 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-203 37
  • 82 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-203a 37
  • 71 (a)
OneToMany
dre-mir-203b 37
  • 72 (a)
OneToMany
Species with no ortholog for MIR203A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR203A Gene

ENSEMBL:
Gene Tree for MIR203A (if available)
TreeFam:
Gene Tree for MIR203A (if available)

Paralogs for MIR203A Gene

No data available for Paralogs for MIR203A Gene

Variants for MIR203A Gene

Sequence variations from dbSNP and Humsavar for MIR203A Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs750062 -- 104,115,423(+) CCAGA(A/G)CTTAG upstream-variant-2KB
rs35459432 -- 104,115,587(+) GTGTG(G/T)TGGTT upstream-variant-2KB
rs35800012 -- 104,116,100(+) CTCAG(-/C)ATCTG upstream-variant-2KB
rs56252815 -- 104,115,613(+) AGCTA(C/T)TTGGG upstream-variant-2KB
rs61997624 -- 104,116,049(+) GGCTG(C/T)GGTGG upstream-variant-2KB

Relevant External Links for MIR203A Gene

HapMap Linkage Disequilibrium report
MIR203A

No data available for Structural Variations from Database of Genomic Variants (DGV) for MIR203A Gene

Disorders for MIR203A Gene

No disorders were found for MIR203A Gene.

No data available for UniProtKB/Swiss-Prot for MIR203A Gene

Publications for MIR203A Gene

  1. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? (PMID: 17622355) Sonkoly E. … Pivarcsi A. (PLoS ONE 2007) 3
  5. miR-203 represses 'stemness' by repressing DeltaNp63. (PMID: 18483491) Lena A.M. … Candi E. (Cell Death Differ. 2008) 3

Products for MIR203A Gene

Sources for MIR203A Gene

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