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Aliases for MIR202 Gene

Subcategory (RNA class) for MIR202 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR202 Gene

  • MicroRNA 202 2 3 5
  • Hsa-Mir-202 3
  • Mir-202 3
  • MIRN202 3

External Ids for MIR202 Gene

Previous HGNC Symbols for MIR202 Gene

  • MIRN202

Previous GeneCards Identifiers for MIR202 Gene

  • GC10M134912
  • GC10M135061

Summaries for MIR202 Gene

Entrez Gene Summary for MIR202 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR202 Gene

MIR202 (MicroRNA 202) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR202 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR202

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR202 Gene

Genomics for MIR202 Gene

Regulatory Elements for MIR202 Gene

Enhancers for MIR202 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G133245 1.5 FANTOM5 ENCODE dbSUPER 0.7 +1.6 1606 1.5 PKNOX1 ATF1 TCF12 GLIS2 ELK1 GATA2 ZNF416 KLF13 SP5 NCOA1 TUBGCP2 MIR202 VENTX
GH10G133240 0.8 Ensembl ENCODE 0.4 +6.2 6168 1.4 ZNF263 SCRT1 GLIS2 MNT REST ZIC2 SPI1 VENTX MIR202
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR202 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR202 Gene

Chromosome:
10
Start:
133,247,511 bp from pter
End:
133,247,620 bp from pter
Size:
110 bases
Orientation:
Minus strand

Genomic View for MIR202 Gene

Genes around MIR202 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR202 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR202 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR202 Gene

ORGUL Member Location for MIR202 Gene

ORGUL Member Location for MIR202 gene

Proteins for MIR202 Gene

Post-translational modifications for MIR202 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR202 Gene

Domains & Families for MIR202 Gene

Gene Families for MIR202 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR202: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR202 Gene

Function for MIR202 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR202 Gene

Localization for MIR202 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR202 Gene

Pathways & Interactions for MIR202 Gene

SuperPathways for MIR202 Gene

No Data Available

Interacting Proteins for MIR202 Gene

Gene Ontology (GO) - Biological Process for MIR202 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR202 Gene

Drugs & Compounds for MIR202 Gene

No Compound Related Data Available

Transcripts for MIR202 Gene

fRNAdb Secondary structures for MIR202 Gene

  • hsa-miR-202-3p_MIMAT0002811_Homo_sapiens_miR-202-3p_mature

mRNA/cDNA for MIR202 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR202 Gene

No ASD Table

Relevant External Links for MIR202 Gene

GeneLoc Exon Structure for
MIR202
ECgene alternative splicing isoforms for
MIR202

Expression for MIR202 Gene

mRNA differential expression in normal tissues according to GTEx for MIR202 Gene

This gene is overexpressed in Testis (x29.0), Adrenal Gland (x16.8), and Ovary (x6.6).

NURSA nuclear receptor signaling pathways regulating expression of MIR202 Gene:

MIR202

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR202 Gene

Orthologs for MIR202 Gene

Evolution for MIR202 Gene

ENSEMBL:
Gene Tree for MIR202 (if available)
TreeFam:
Gene Tree for MIR202 (if available)

No data available for Orthologs for MIR202 Gene

Paralogs for MIR202 Gene

No data available for Paralogs for MIR202 Gene

Variants for MIR202 Gene

Sequence variations from dbSNP and Humsavar for MIR202 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1001044773 -- 133,248,554(+) GAGGG(-/C)CCCTC upstream-variant-2KB
rs1001784746 -- 133,248,106(+) CTGGG(A/G)TGGGG upstream-variant-2KB
rs1001936154 -- 133,247,429(+) CCCGG(A/C)CGAGG intron-variant, downstream-variant-500B
rs1002196077 -- 133,247,957(+) CAGAG(A/G)GCTGC upstream-variant-2KB
rs1003408305 -- 133,247,210(+) GTCAG(A/T)CTGGT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR202 Gene

Variant ID Type Subtype PubMed ID
dgv2e196 CNV duplication 17116639
esv2759793 CNV gain+loss 17122850
esv2760107 CNV gain 21179565
esv3625030 CNV gain 21293372
esv3625035 CNV gain 21293372
nsv1159784 CNV deletion 26073780
nsv1159785 CNV deletion 26073780
nsv1159786 CNV deletion 26073780
nsv428243 CNV gain 18775914
nsv470980 CNV loss 18288195
nsv509381 CNV insertion 20534489
nsv516968 CNV loss 19592680
nsv528260 CNV loss 19592680
nsv552574 CNV gain 21841781
nsv832036 CNV loss 17160897
nsv832038 CNV gain+loss 17160897
nsv832039 CNV loss 17160897
nsv8750 CNV gain+loss 18304495
nsv952705 CNV deletion 24416366

Relevant External Links for MIR202 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR202

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR202 Gene

Disorders for MIR202 Gene

Relevant External Links for MIR202

Human Genome Epidemiology (HuGE) Navigator
MIR202
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR202

No disorders were found for MIR202 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR202 Gene

Publications for MIR202 Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 1 3 64
  2. miR-202 Promotes Cell Apoptosis in Esophageal Squamous Cell Carcinoma by Targeting HSF2. (PMID: 28277193) Meng X. … Fan Q. (Oncol. Res. 2017) 3 64
  3. MicroRNA-202-3p regulates scleroderma fibrosis by targeting matrix metalloproteinase 1. (PMID: 28068631) Zhou B. … Zuo X. (Biomed. Pharmacother. 2017) 3 64
  4. Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 regulates the expression of Gli2 by miR-202 to strengthen gastric cancer progression. (PMID: 27887846) Zhang Y. … Jing N.C. (Biomed. Pharmacother. 2017) 3 64
  5. MicroRNA-202 inhibits tumor progression by targeting LAMA1 in esophageal squamous cell carcinoma. (PMID: 27045085) Meng X. … Fan Q. (Biochem. Biophys. Res. Commun. 2016) 3 64

Products for MIR202 Gene

Sources for MIR202 Gene

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