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Aliases for MIR200C Gene

Subcategory (RNA class) for MIR200C Gene


Quality Score for this RNA gene is


Aliases for MIR200C Gene

  • MicroRNA 200c 2 3
  • MIRN200C 3 6
  • Hsa-Mir-200c 3

External Ids for MIR200C Gene

ORGUL Members for MIR200C Gene

Previous HGNC Symbols for MIR200C Gene

  • MIRN200C

Previous GeneCards Identifiers for MIR200C Gene

  • GC12P006971
  • GC12P006974
  • GC12P007072

Summaries for MIR200C Gene

Entrez Gene Summary for MIR200C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR200C Gene

MIR200C (MicroRNA 200c) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR200C include intrahepatic cholangiocarcinoma and esophageal cancer. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR200C Gene

Genomics for MIR200C Gene

Genomic Location for MIR200C Gene

6,963,672 bp from pter
6,963,780 bp from pter
109 bases
Plus strand

Genomic View for MIR200C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR200C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR200C Gene

No data available for Regulatory Elements for MIR200C Gene

Proteins for MIR200C Gene

Post-translational modifications for MIR200C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR200C Gene

Domains for MIR200C Gene

Gene Families for MIR200C Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR200C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR200C Gene

Function for MIR200C Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR200C Gene

Localization for MIR200C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR200C Gene

Pathways for MIR200C Gene

SuperPathways for MIR200C Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR200C: view

Pathways by source for MIR200C Gene

1 KEGG pathway for MIR200C Gene

Interacting Proteins for MIR200C Gene

Gene Ontology (GO) - Biological Process for MIR200C Gene


Transcripts for MIR200C Gene

mRNA/cDNA for MIR200C Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR200C Gene

No ASD Table

Relevant External Links for MIR200C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR200C Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR200C Gene

Orthologs for MIR200C Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR200C Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-200c 36
  • 85 (a)
(Canis familiaris)
Mammalia cfa-mir-200c 36
  • 85 (a)
(Monodelphis domestica)
Mammalia mdo-mir-200c 36
  • 91 (a)
(Mus musculus)
Mammalia Mir200c 36
  • 72 (a)
(Pan troglodytes)
Mammalia ptr-mir-200c 36
  • 100 (a)
(Danio rerio)
Actinopterygii dre-mir-200c 36
  • 48 (a)
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-141 36
  • 44 (a)
Species with no ortholog for MIR200C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR200C Gene

Gene Tree for MIR200C (if available)
Gene Tree for MIR200C (if available)

Paralogs for MIR200C Gene

No data available for Paralogs for MIR200C Gene

Variants for MIR200C Gene

Sequence variations from dbSNP and Humsavar for MIR200C Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs73262897 -- 6,961,967(+) GGCAC(A/G)CCCAG upstream-variant-2KB
rs113837888 -- 6,961,966(+) GGGCA(C/T)GCCCA upstream-variant-2KB
rs138602529 -- 6,961,825(+) GGGGG(A/G)CCCTG upstream-variant-2KB
rs142710585 -- 6,961,893(+) GGAAG(C/T)GCAGA upstream-variant-2KB
rs144584064 -- 6,961,961(+) CACCC(A/G)GGCAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR200C Gene

Variant ID Type Subtype PubMed ID
nsv898641 CNV Loss 21882294
nsv509453 CNV Insertion 20534489

Relevant External Links for MIR200C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR200C Gene

Disorders for MIR200C Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for MIR200C Gene in MalaCards »

(2) Diseases for MIR200C Gene including...

Relevant External Links for MIR200C

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with MIR200C: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR200C Gene

Publications for MIR200C Gene

  1. Reduced accumulation of specific microRNAs in colorectal neoplasia. (PMID: 14573789) Michael M.Z. … James R.J. (Mol. Cancer Res. 2003) 3
  2. Human embryonic stem cells express a unique set of microRNAs. (PMID: 15183728) Suh M.R. … Kim K.S. (Dev. Biol. 2004) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3

Products for MIR200C Gene

Sources for MIR200C Gene

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