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Aliases for MIR200A Gene

Subcategory (RNA class) for MIR200A Gene


Quality Score for this RNA gene is


Aliases for MIR200A Gene

  • MicroRNA 200a 2 3 5
  • Hsa-Mir-200a 3
  • Mir-200a 3
  • MIRN200A 3

External Ids for MIR200A Gene

ORGUL Members for MIR200A Gene

Previous HGNC Symbols for MIR200A Gene

  • MIRN200A

Previous GeneCards Identifiers for MIR200A Gene

  • GC01P001101
  • GC01P001104
  • GC01P001107
  • GC01P001115
  • GC01P001128
  • GC01P001169
  • GC01P001174
  • GC01P001179

Summaries for MIR200A Gene

Entrez Gene Summary for MIR200A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR200A Gene

MIR200A (MicroRNA 200a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR200A Gene

Genomics for MIR200A Gene

Regulatory Elements for MIR200A Gene

Enhancers for MIR200A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F001189 1 FANTOM5 13.6 +21.5 21529 0.3 MLX ZFP64 ARID4B DMAP1 RAD21 THRB YY1 RARA GATA4 THAP11 SDF4 B3GALT6 MIR200A MIR200B MIR429 LINC01786 UBE2J2 FAM132A SLC35E2 TNFRSF18
GH01F001109 0.9 ENCODE 11.6 -58.0 -58005 1.1 HDAC1 PKNOX1 CBX3 ATF1 NFRKB ZBTB40 YY1 ZEB1 GATA2 CREM UBE2J2 LINC01786 MIR429 MIR200B MIR200A PERM1 PLEKHN1 ENSG00000239906 C1orf159 GC01M001107
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR200A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR200A Gene

1,167,863 bp from pter
1,167,952 bp from pter
90 bases
Plus strand

Genomic View for MIR200A Gene

Genes around MIR200A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR200A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR200A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR200A Gene

Proteins for MIR200A Gene

Post-translational modifications for MIR200A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR200A Gene

Domains & Families for MIR200A Gene

Gene Families for MIR200A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR200A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR200A Gene

Function for MIR200A Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR200A Gene

Localization for MIR200A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR200A Gene

Pathways & Interactions for MIR200A Gene

SuperPathways for MIR200A Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR200A: view

Pathways by source for MIR200A Gene

1 KEGG pathway for MIR200A Gene

Interacting Proteins for MIR200A Gene

Gene Ontology (GO) - Biological Process for MIR200A Gene


No data available for SIGNOR curated interactions for MIR200A Gene

Transcripts for MIR200A Gene

mRNA/cDNA for MIR200A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR200A Gene

No ASD Table

Relevant External Links for MIR200A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR200A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR200A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR200A Gene:

genes like me logo Genes that share expression patterns with MIR200A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR200A Gene

Orthologs for MIR200A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR200A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-200a 35
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-200a 35
  • 93 (a)
(Canis familiaris)
Mammalia cfa-mir-200a 35
  • 92 (a)
(Mus musculus)
Mammalia Mir200a 35
  • 92 (a)
(Monodelphis domestica)
Mammalia mdo-mir-200a 35
  • 79 (a)
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-141 35
  • 56 (a)
Species where no ortholog for MIR200A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR200A Gene

Gene Tree for MIR200A (if available)
Gene Tree for MIR200A (if available)

Paralogs for MIR200A Gene

No data available for Paralogs for MIR200A Gene

Variants for MIR200A Gene

Sequence variations from dbSNP and Humsavar for MIR200A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111233725 -- 1,166,160(+) CCAGT(G/T)GGCAC upstream-variant-2KB
rs111652490 -- 1,167,980(+) GGCAC(A/G)TCCGG downstream-variant-500B, upstream-variant-2KB
rs112604916 -- 1,168,157(+) AGCTC(C/T)GAAGT downstream-variant-500B, upstream-variant-2KB
rs11260534 -- 1,166,992(+) CACCC(A/G)GGCCC upstream-variant-2KB
rs112823253 -- 1,166,860(+) CAGAG(A/G)GCCCG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR200A Gene

Variant ID Type Subtype PubMed ID
dgv2n67 CNV gain 20364138
nsv1003578 CNV gain 25217958
nsv10161 CNV gain+loss 18304495
nsv1160644 CNV deletion 26073780
nsv1160772 CNV duplication 26073780
nsv428334 CNV gain 18775914
nsv469848 CNV gain 16826518
nsv470680 CNV loss 18288195
nsv482937 CNV loss 15286789
nsv509257 CNV insertion 20534489
nsv517709 CNV gain+loss 19592680
nsv544947 CNV loss 21841781
nsv544954 CNV loss 21841781
nsv950452 CNV deletion 24416366

Relevant External Links for MIR200A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR200A Gene

Disorders for MIR200A Gene

Relevant External Links for MIR200A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR200A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR200A Gene

Publications for MIR200A Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 46 64
  2. MicroRNA-200a mediates nasopharyngeal carcinoma cell proliferation through the activation of nuclear factor-I_B. (PMID: 26718506) Shi Z. … Huang F. (Mol Med Rep 2016) 3 64
  3. MicroRNA-200a-3p suppresses tumor proliferation and induces apoptosis by targeting SPAG9 in renal cell carcinoma. (PMID: 26797273) Wang X. … Gu X. (Biochem. Biophys. Res. Commun. 2016) 3 64
  4. GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification. (PMID: 26887977) Chung V.Y. … Huang R.Y. (Sci Rep 2016) 3 64
  5. Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling. (PMID: 26068592) Tang X. … Liu M. (Cell Death Differ. 2016) 3 64

Products for MIR200A Gene

Sources for MIR200A Gene

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