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Aliases for MIR19B2 Gene

Subcategory (RNA class) for MIR19B2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR19B2 Gene

  • MicroRNA 19b-2 2 3 5
  • Hsa-Mir-19b-2 3
  • MiR-19b-2 3
  • MIRN19B2 3

External Ids for MIR19B2 Gene

Previous HGNC Symbols for MIR19B2 Gene

  • MIRN19B2

Previous GeneCards Identifiers for MIR19B2 Gene

  • GC0XM133152
  • GC0XM133159
  • GC0XM133306
  • GC0XM133311
  • GC0XM133315
  • GC0XM133319
  • GC0XM133324
  • GC0XM133328
  • GC0XM133332
  • GC0XM133336
  • GC0XM133338
  • GC0XM133349
  • GC0XM133373
  • GC0XM134172
  • GC0XM134177

Summaries for MIR19B2 Gene

Entrez Gene Summary for MIR19B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR19B2 Gene

MIR19B2 (MicroRNA 19b-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Parkinsons Disease Pathway and MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR19B2 Gene

Genomics for MIR19B2 Gene

Regulatory Elements for MIR19B2 Gene

Enhancers for MIR19B2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF134171 1.3 FANTOM5 Ensembl ENCODE 0.8 +0.5 455 4.8 MAX ZNF76 ZIC2 ZNF664 ZFHX2 GLIS2 POLR2A PATZ1 ZNF143 PRDM10 CCDC160 GPC3 PHF6 GC0XM134196 GC0XM134201 MIR92A2 MIR106A MIR18B MIR19B2 MIR20B
GH0XF134179 0.2 ENCODE 0.4 -6.9 -6879 2.4 ZNF133 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
GH0XF134187 0.2 Ensembl 0.4 -13.2 -13212 0.2 CBX8 CCDC160 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
GH0XF134186 0.4 ENCODE 0.4 -12.9 -12857 0.2 CBX8 CCDC160 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
GH0XF134188 0.2 Ensembl 0.4 -12.4 -12412 0.2 CCDC160 MIR106A MIR18B MIR19B2 MIR20B MIR363 MIR92A2 LARP1BP3
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR19B2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR19B2 Gene

Chromosome:
X
Start:
134,168,911 bp from pter
End:
134,174,089 bp from pter
Size:
5,179 bases
Orientation:
Minus strand

Genomic View for MIR19B2 Gene

Genes around MIR19B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR19B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR19B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR19B2 Gene

Proteins for MIR19B2 Gene

Post-translational modifications for MIR19B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR19B2 Gene

Domains & Families for MIR19B2 Gene

Gene Families for MIR19B2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR19B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR19B2 Gene

Function for MIR19B2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR19B2 Gene

Localization for MIR19B2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR19B2 Gene

Pathways & Interactions for MIR19B2 Gene

genes like me logo Genes that share pathways with MIR19B2: view

Pathways by source for MIR19B2 Gene

1 BioSystems pathway for MIR19B2 Gene
1 KEGG pathway for MIR19B2 Gene

Interacting Proteins for MIR19B2 Gene

Gene Ontology (GO) - Biological Process for MIR19B2 Gene

None

No data available for SIGNOR curated interactions for MIR19B2 Gene

Transcripts for MIR19B2 Gene

mRNA/cDNA for MIR19B2 Gene

(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR19B2 Gene

No ASD Table

Relevant External Links for MIR19B2 Gene

GeneLoc Exon Structure for
MIR19B2
ECgene alternative splicing isoforms for
MIR19B2

Expression for MIR19B2 Gene

mRNA expression in normal human tissues for MIR19B2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR19B2 Gene:

MIR19B2
genes like me logo Genes that share expression patterns with MIR19B2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR19B2 Gene

Orthologs for MIR19B2 Gene

Evolution for MIR19B2 Gene

ENSEMBL:
Gene Tree for MIR19B2 (if available)
TreeFam:
Gene Tree for MIR19B2 (if available)

No data available for Orthologs for MIR19B2 Gene

Paralogs for MIR19B2 Gene

No data available for Paralogs for MIR19B2 Gene

Variants for MIR19B2 Gene

Sequence variations from dbSNP and Humsavar for MIR19B2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs113658998 -- 134,170,166(+) CACAA(A/G)CTACA downstream-variant-500B, upstream-variant-2KB
rs137881717 -- 134,171,170(+) TAAAC(A/G)AGTGA upstream-variant-2KB
rs142112727 -- 134,171,521(+) TCTGG(C/T)ATCCC upstream-variant-2KB
rs142600536 -- 134,169,291(+) ATTAT(C/T)TTTTA downstream-variant-500B
rs142900355 -- 134,169,185(+) TGAGG(C/T)TCATT downstream-variant-500B

Relevant External Links for MIR19B2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR19B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR19B2 Gene

Disorders for MIR19B2 Gene

Relevant External Links for MIR19B2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR19B2

No disorders were found for MIR19B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR19B2 Gene

Publications for MIR19B2 Gene

  1. Diosgenin inhibits atherosclerosis via suppressing the MiR-19b-induced downregulation of ATP-binding cassette transporter A1. (PMID: 25765596) Lv Y.C. … Tang C.K. (Atherosclerosis 2015) 3 64
  2. MicroRNA-19b promotes macrophage cholesterol accumulation and aortic atherosclerosis by targeting ATP-binding cassette transporter A1. (PMID: 25084135) Lv Y.C. … Tang C.K. (Atherosclerosis 2014) 3 64
  3. MiR-17-92 cluster: an apoptosis inducer or proliferation enhancer. (PMID: 23681423) Ranji N. … Azadmanesh K. (Mol. Cell. Biochem. 2013) 3 64
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3 64

Products for MIR19B2 Gene

Sources for MIR19B2 Gene

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