Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR19B2 Gene

Subcategory (RNA class) for MIR19B2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR19B2 Gene

  • MicroRNA 19b-2 2 3
  • Hsa-Mir-19b-2 3
  • MiR-19b-2 3
  • MIRN19B2 3

External Ids for MIR19B2 Gene

Previous HGNC Symbols for MIR19B2 Gene

  • MIRN19B2

Previous GeneCards Identifiers for MIR19B2 Gene

  • GC0XM133152
  • GC0XM133159
  • GC0XM133306
  • GC0XM133311
  • GC0XM133315
  • GC0XM133319
  • GC0XM133324
  • GC0XM133328
  • GC0XM133332
  • GC0XM133336
  • GC0XM133338
  • GC0XM133349
  • GC0XM133373
  • GC0XM134172

Summaries for MIR19B2 Gene

Entrez Gene Summary for MIR19B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR19B2 Gene

MIR19B2 (MicroRNA 19b-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR19B2 Gene

Genomics for MIR19B2 Gene

Genomic Location for MIR19B2 Gene

Chromosome:
X
Start:
134,169,671 bp from pter
End:
134,169,767 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR19B2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR19B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR19B2 Gene

No data available for Regulatory Elements for MIR19B2 Gene

Proteins for MIR19B2 Gene

Post-translational modifications for MIR19B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR19B2 Gene

Domains & Families for MIR19B2 Gene

Gene Families for MIR19B2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR19B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR19B2 Gene

Function for MIR19B2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR19B2 Gene

Localization for MIR19B2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR19B2 Gene

Pathways & Interactions for MIR19B2 Gene

SuperPathways for MIR19B2 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR19B2: view

Pathways by source for MIR19B2 Gene

1 KEGG pathway for MIR19B2 Gene

Interacting Proteins for MIR19B2 Gene

Gene Ontology (GO) - Biological Process for MIR19B2 Gene

None

No data available for SIGNOR curated interactions for MIR19B2 Gene

Drugs & Compounds for MIR19B2 Gene

No Compound Related Data Available

Transcripts for MIR19B2 Gene

mRNA/cDNA for MIR19B2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR19B2 Gene

No ASD Table

Relevant External Links for MIR19B2 Gene

GeneLoc Exon Structure for
MIR19B2
ECgene alternative splicing isoforms for
MIR19B2

Expression for MIR19B2 Gene

mRNA expression in normal human tissues for MIR19B2 Gene

genes like me logo Genes that share expression patterns with MIR19B2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR19B2 Gene

Orthologs for MIR19B2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR19B2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-19b-2 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-19b-2 36
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-19b-2 36
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir19b-2 36
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-19b-1 36
  • 72 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-19b-2 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 36
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 71 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-19c 36
  • 58 (a)
OneToMany
dre-mir-19d 36
  • 57 (a)
OneToMany
Species with no ortholog for MIR19B2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR19B2 Gene

ENSEMBL:
Gene Tree for MIR19B2 (if available)
TreeFam:
Gene Tree for MIR19B2 (if available)

Paralogs for MIR19B2 Gene

No data available for Paralogs for MIR19B2 Gene

Variants for MIR19B2 Gene

Relevant External Links for MIR19B2 Gene

HapMap Linkage Disequilibrium report
MIR19B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR19B2 Gene

Disorders for MIR19B2 Gene

Relevant External Links for MIR19B2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR19B2
genes like me logo Genes that share disorders with MIR19B2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR19B2 Gene

Publications for MIR19B2 Gene

  1. MicroRNA-19b promotes macrophage cholesterol accumulation and aortic atherosclerosis by targeting ATP-binding cassette transporter A1. (PMID: 25084135) Lv Y.C. … Tang C.K. (Atherosclerosis 2014) 67
  2. MiR-17-92 cluster: an apoptosis inducer or proliferation enhancer. (PMID: 23681423) Ranji N. … Azadmanesh K. (Mol. Cell. Biochem. 2013) 67
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 67
  4. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 67
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 67

Products for MIR19B2 Gene

Sources for MIR19B2 Gene

Back to Top

Content