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Aliases for MIR19B1 Gene

Subcategory (RNA class) for MIR19B1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR19B1 Gene

  • MicroRNA 19b-1 2 3
  • MIRN19B1 3 6
  • Hsa-Mir-19b-1 3
  • MiR-19b-1 3
  • MiRNA19B1 3

External Ids for MIR19B1 Gene

Previous HGNC Symbols for MIR19B1 Gene

  • MIRN19B1

Previous GeneCards Identifiers for MIR19B1 Gene

  • GC13P090873
  • GC13P090881
  • GC13P092011
  • GC13P092020
  • GC13P092027
  • GC13P092035
  • GC13P092044
  • GC13P092054
  • GC13P092063
  • GC13P092073
  • GC13P092082

Summaries for MIR19B1 Gene

Entrez Gene Summary for MIR19B1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. This miRNA belongs to a polycistronic miRNA cluster that includes six consecutive mature miRNAs that are derived from a single primary transcript. The mature miRNAs of this cluster are often overexpressed in solid cancers. [provided by RefSeq, May 2012]

GeneCards Summary for MIR19B1 Gene

MIR19B1 (MicroRNA 19b-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR19B1 Gene

Genomics for MIR19B1 Gene

Genomic Location for MIR19B1 Gene

Start:
91,351,192 bp from pter
End:
91,351,278 bp from pter
Size:
87 bases
Orientation:
Plus strand

Genomic View for MIR19B1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR19B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR19B1 Gene

No data available for Regulatory Elements for MIR19B1 Gene

Proteins for MIR19B1 Gene

Post-translational modifications for MIR19B1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR19B1 Gene

Domains for MIR19B1 Gene

Gene Families for MIR19B1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR19B1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR19B1 Gene

Function for MIR19B1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR19B1 Gene

Localization for MIR19B1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR19B1 Gene

Pathways for MIR19B1 Gene

genes like me logo Genes that share pathways with MIR19B1: view

Pathways by source for MIR19B1 Gene

1 BioSystems pathway for MIR19B1 Gene
1 KEGG pathway for MIR19B1 Gene

Interacting Proteins for MIR19B1 Gene

Gene Ontology (GO) - Biological Process for MIR19B1 Gene

None

Transcripts for MIR19B1 Gene

mRNA/cDNA for MIR19B1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR19B1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR19B1 Gene

No ASD Table

Relevant External Links for MIR19B1 Gene

GeneLoc Exon Structure for
MIR19B1
ECgene alternative splicing isoforms for
MIR19B1

Expression for MIR19B1 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR19B1 Gene

Orthologs for MIR19B1 Gene

Evolution for MIR19B1 Gene

ENSEMBL:
Gene Tree for MIR19B1 (if available)
TreeFam:
Gene Tree for MIR19B1 (if available)

No data available for Orthologs for MIR19B1 Gene

Paralogs for MIR19B1 Gene

No data available for Paralogs for MIR19B1 Gene

Variants for MIR19B1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR19B1 Gene

Variant ID Type Subtype PubMed ID
nsv832679 CNV Gain 17160897

Relevant External Links for MIR19B1 Gene

HapMap Linkage Disequilibrium report
MIR19B1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR19B1 Gene

Disorders for MIR19B1 Gene

No disorders were found for MIR19B1 Gene.

No data available for UniProtKB/Swiss-Prot for MIR19B1 Gene

Publications for MIR19B1 Gene

  1. Identification of novel genes coding for small expressed RNAs. (PMID: 11679670) Lagos-Quintana M. … Tuschl T. (Science 2001) 3
  2. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. (PMID: 11914277) Mourelatos Z. … Dreyfuss G. (Genes Dev. 2002) 3
  3. Numerous microRNPs in neuronal cells containing novel microRNAs. (PMID: 12554860) Dostie J. … Dreyfuss G. (RNA 2003) 3
  4. Reduced accumulation of specific microRNAs in colorectal neoplasia. (PMID: 14573789) Michael M.Z. … James R.J. (Mol. Cancer Res. 2003) 3
  5. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. (PMID: 15126345) Ota A. … Seto M. (Cancer Res. 2004) 3

Products for MIR19B1 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR19B1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR19B1
    • Block miRNA regulation of MIR19B1 using miScript Target Protectors

    Sources for MIR19B1 Gene

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