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Aliases for MIR19A Gene

Subcategory (RNA class) for MIR19A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR19A Gene

  • MicroRNA 19a 2 3
  • MIRN19A 3 6
  • Hsa-Mir-19a 3
  • MiRNA19A 3
  • MiR-19a 3

External Ids for MIR19A Gene

Previous HGNC Symbols for MIR19A Gene

  • MIRN19A

Previous GeneCards Identifiers for MIR19A Gene

  • GC13P090871
  • GC13P090879
  • GC13P092008
  • GC13P092017
  • GC13P092025
  • GC13P092033
  • GC13P092042
  • GC13P092052
  • GC13P092060
  • GC13P092070
  • GC13P092081

Summaries for MIR19A Gene

Entrez Gene Summary for MIR19A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. This miRNA belongs to a polycistronic miRNA cluster that includes six consecutive mature miRNAs that are derived from a single primary transcript. The mature miRNAs of this cluster are often overexpressed in solid cancers. [provided by RefSeq, May 2012]

GeneCards Summary for MIR19A Gene

MIR19A (MicroRNA 19a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR19A Gene

Genomics for MIR19A Gene

Genomic Location for MIR19A Gene

Start:
91,350,891 bp from pter
End:
91,350,972 bp from pter
Size:
82 bases
Orientation:
Plus strand

Genomic View for MIR19A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR19A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR19A Gene

No data available for Regulatory Elements for MIR19A Gene

Proteins for MIR19A Gene

Post-translational modifications for MIR19A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR19A Gene

Domains for MIR19A Gene

Gene Families for MIR19A Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR19A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR19A Gene

Function for MIR19A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR19A Gene

Localization for MIR19A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR19A Gene

Pathways for MIR19A Gene

genes like me logo Genes that share pathways with MIR19A: view

Pathways by source for MIR19A Gene

1 BioSystems pathway for MIR19A Gene
1 KEGG pathway for MIR19A Gene

Interacting Proteins for MIR19A Gene

Gene Ontology (GO) - Biological Process for MIR19A Gene

None

Transcripts for MIR19A Gene

mRNA/cDNA for MIR19A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR19A Gene

No ASD Table

Relevant External Links for MIR19A Gene

GeneLoc Exon Structure for
MIR19A
ECgene alternative splicing isoforms for
MIR19A

Expression for MIR19A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with MIR19A: view

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR19A Gene

Orthologs for MIR19A Gene

Evolution for MIR19A Gene

ENSEMBL:
Gene Tree for MIR19A (if available)
TreeFam:
Gene Tree for MIR19A (if available)

No data available for Orthologs for MIR19A Gene

Paralogs for MIR19A Gene

No data available for Paralogs for MIR19A Gene

Variants for MIR19A Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR19A Gene

Variant ID Type Subtype PubMed ID
nsv832679 CNV Gain 17160897

Relevant External Links for MIR19A Gene

HapMap Linkage Disequilibrium report
MIR19A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR19A Gene

Disorders for MIR19A Gene

Relevant External Links for MIR19A

Genetic Association Database (GAD)
MIR19A
Human Genome Epidemiology (HuGE) Navigator
MIR19A
genes like me logo Genes that share disorders with MIR19A: view

No data available for UniProtKB/Swiss-Prot for MIR19A Gene

Publications for MIR19A Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 48
  2. MicroRNA-dependent regulation of PTEN after arsenic trioxide treatment in bladder cancer cell line T24. (PMID: 20857258) Cao Y. … An R.H. (Tumour Biol. 2011) 3
  3. MicroRNA-19 (miR-19) regulates tissue factor expression in breast cancer cells. (PMID: 21059650) Zhang X. … Ding W.Q. (J. Biol. Chem. 2011) 3
  4. TNF-I+ is a novel target of miR-19a. (PMID: 21271217) Liu M. … Xu N. (Int. J. Oncol. 2011) 3
  5. TLR2 expression is regulated by microRNA miR-19 in rheumatoid fibroblast-like synoviocytes. (PMID: 22105995) Philippe L. … Pfeffer S. (J. Immunol. 2012) 3

Products for MIR19A Gene

Sources for MIR19A Gene

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