Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR199A2 Gene

Subcategory (RNA class) for MIR199A2 Gene


Quality Score for this RNA gene is


Aliases for MIR199A2 Gene

  • MicroRNA 199a-2 2 3
  • Hsa-Mir-199a-2 3
  • MiR-199a-3p 3
  • Mir-199a-2 3
  • MIR-199-S 3
  • MIRN199A2 3

External Ids for MIR199A2 Gene

Previous HGNC Symbols for MIR199A2 Gene

  • MIRN199A2

Previous GeneCards Identifiers for MIR199A2 Gene

  • GC01M170381
  • GC01M172181
  • GC01M172184
  • GC01M172190
  • GC01M172194

Summaries for MIR199A2 Gene

Entrez Gene Summary for MIR199A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR199A2 Gene

MIR199A2 (MicroRNA 199a-2) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are MicroRNAs in cancer and MicroRNAs in cardiomyocyte hypertrophy.

fRNAdb sequence ontologies for MIR199A2 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR199A2 Gene

Genomics for MIR199A2 Gene

Genomic Location for MIR199A2 Gene

172,144,535 bp from pter
172,144,644 bp from pter
110 bases
Minus strand

Genomic View for MIR199A2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR199A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR199A2 Gene

ORGUL Member Location for MIR199A2 Gene

ORGUL Member Location for MIR199A2 gene

No data available for Regulatory Elements for MIR199A2 Gene

Proteins for MIR199A2 Gene

Post-translational modifications for MIR199A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR199A2 Gene

Domains & Families for MIR199A2 Gene

Gene Families for MIR199A2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR199A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR199A2 Gene

Function for MIR199A2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR199A2 Gene

Localization for MIR199A2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR199A2 Gene

Pathways & Interactions for MIR199A2 Gene

genes like me logo Genes that share pathways with MIR199A2: view

Pathways by source for MIR199A2 Gene

1 BioSystems pathway for MIR199A2 Gene
1 KEGG pathway for MIR199A2 Gene

Interacting Proteins for MIR199A2 Gene

Gene Ontology (GO) - Biological Process for MIR199A2 Gene


No data available for SIGNOR curated interactions for MIR199A2 Gene

Drugs & Compounds for MIR199A2 Gene

No Compound Related Data Available

Transcripts for MIR199A2 Gene

mRNA/cDNA for MIR199A2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR199A2 Gene

No ASD Table

Relevant External Links for MIR199A2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR199A2 Gene

mRNA expression in normal human tissues for MIR199A2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR199A2 Gene

This gene is overexpressed in Ovary (x5.7).
genes like me logo Genes that share expression patterns with MIR199A2: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR199A2 Gene

Orthologs for MIR199A2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR199A2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-199a-1 36
  • 99 (a)
(Canis familiaris)
Mammalia cfa-mir-199-2 36
  • 99 (a)
(Monodelphis domestica)
Mammalia mdo-mir-199b-2 36
  • 96 (a)
(Mus musculus)
Mammalia Mir199a-2 36
  • 96 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-199 36
  • 87 (a)
(Pan troglodytes)
Mammalia ptr-mir-199a-2 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-199-2 36
  • 96 (a)
(Anolis carolinensis)
Reptilia aca-mir-199a-2 36
  • 83 (a)
(Danio rerio)
Actinopterygii dre-mir-199-1 36
  • 90 (a)
Species with no ortholog for MIR199A2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR199A2 Gene

Gene Tree for MIR199A2 (if available)
Gene Tree for MIR199A2 (if available)

Paralogs for MIR199A2 Gene

No data available for Paralogs for MIR199A2 Gene

Variants for MIR199A2 Gene

Relevant External Links for MIR199A2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR199A2 Gene

Disorders for MIR199A2 Gene

Relevant External Links for MIR199A2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR199A2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR199A2 Gene

Publications for MIR199A2 Gene

  1. CCL5 promotes vascular endothelial growth factor expression and induces angiogenesis by down-regulating miR-199a in human chondrosarcoma cells. (PMID: 25444917) Liu G.T. … Tang C.H. (Cancer Lett. 2015) 67
  2. MiR-199a inhibits the ability of proliferation and migration by regulating CD44-Ezrin signaling in cutaneous squamous cell carcinoma cells. (PMID: 25400809) Wang S.H. … Luo C.Q. (Int J Clin Exp Pathol 2014) 67
  3. MiR-199a-3p promotes gastric cancer progression by targeting ZHX1. (PMID: 25448600) Wang Z. … Li C. (FEBS Lett. 2014) 67
  4. Blunted expression of miR-199a-5p in regulatory T cells of patients with chronic obstructive pulmonary disease compared to unaffected smokers. (PMID: 24634990) Chatila W.M. … Rogers T.J. (Clin. Exp. Immunol. 2014) 67
  5. MiR-199a regulates cell proliferation and survival by targeting FZD7. (PMID: 25313882) Song J. … Fan D. (PLoS ONE 2014) 67

Products for MIR199A2 Gene

Sources for MIR199A2 Gene

Back to Top