Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR199A1 Gene

Subcategory (RNA class) for MIR199A1 Gene

miRNA

Quality Score for this RNA gene is

10.2

Aliases for MIR199A1 Gene

  • MicroRNA 199a-1 2 3
  • MIRN199A1 3 6
  • Hsa-Mir-199a-1 3
  • MIR-199-S 3

External Ids for MIR199A1 Gene

Previous Symbols for MIR199A1 Gene

  • MIRN199A1

Summaries for MIR199A1 Gene

Entrez Gene Summary for MIR199A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR199A1 Gene

MIR199A1 (MicroRNA 199a-1) is a RNA Gene, and belongs to miRNA RNA class. Among its related pathways are MicroRNAs in cancer and MicroRNAs in cardiomyocyte hypertrophy.

fRNAdb sequence ontologies for MIR199A1 Gene - the ORGUL cluster for this gene includes several descriptions:

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR199A1

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR199A1 Gene

Genomics for MIR199A1 Gene

Genomic Location for MIR199A1 Gene

Start:
10,817,426 bp from pter
End:
10,817,496 bp from pter
Size:
71 bases
Orientation:
Minus strand

Genomic View for MIR199A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR199A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR199A1 Gene

ORGUL Member Location for MIR199A1 Gene

ORGUL Member Location for MIR199A1 gene

No data available for Regulatory Elements for MIR199A1 Gene

Proteins for MIR199A1 Gene

Post-translational modifications for MIR199A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR199A1 Gene

Domains for MIR199A1 Gene

Gene Families for MIR199A1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR199A1: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR199A1 Gene

Function for MIR199A1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR199A1 Gene

Localization for MIR199A1 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR199A1 Gene

Pathways for MIR199A1 Gene

genes like me logo Genes that share pathways with MIR199A1: view

Pathways by source for MIR199A1 Gene

Interacting Proteins for MIR199A1 Gene

Gene Ontology (GO) - Biological Process for MIR199A1 Gene

None

Transcripts for MIR199A1 Gene

fRNAdb Secondary structures for MIR199A1 Gene

  • FR299132
  • hsa-mir-199a-1_MI0000242_Homo_sapiens_miR-199a-1_stem-loop_hairpin
  • hsa-miR-199b-3p_MIMAT0004563_Homo_sapiens_miR-199b-3p_mature

mRNA/cDNA for MIR199A1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR199A1 Gene

No ASD Table

Relevant External Links for MIR199A1 Gene

GeneLoc Exon Structure for
MIR199A1
ECgene alternative splicing isoforms for
MIR199A1

Expression for MIR199A1 Gene

mRNA expression in normal human tissues for MIR199A1 Gene

genes like me logo Genes that share expressions with MIR199A1: view

Orthologs for MIR199A1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR199A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-199a-1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-3604-1 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-199-1 37
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir199a-1 37
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-199b-3 37
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-199a-1 37
  • 57 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-199-2 37
  • 63 (a)
ManyToMany
Species with no ortholog for MIR199A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR199A1 Gene

ENSEMBL:
Gene Tree for MIR199A1 (if available)
TreeFam:
Gene Tree for MIR199A1 (if available)

Paralogs for MIR199A1 Gene

No data available for Paralogs for MIR199A1 Gene

Variants for MIR199A1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR199A1 Gene

Variant ID Type Subtype PubMed ID
nsv833746 CNV Loss 17160897
nsv833748 CNV Loss 17160897
nsv911049 CNV Loss 21882294
nsv2416 CNV Insertion 18451855

Relevant External Links for MIR199A1 Gene

HapMap Linkage Disequilibrium report
MIR199A1

No data available for Sequence variations from dbSNP and Humsavar for MIR199A1 Gene

Disorders for MIR199A1 Gene

No disorders were found for MIR199A1 Gene.

No data available for UniProtKB/Swiss-Prot for MIR199A1 Gene

Publications for MIR199A1 Gene

  1. New microRNAs from mouse and human. (PMID: 12554859) Lagos-Quintana M. … Tuschl T. (RNA 2003) 3
  2. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 3
  3. Identification of human fetal liver miRNAs by a novel method. (PMID: 15978578) Fu H. … Zheng X. (FEBS Lett. 2005) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR199A1 Gene

Sources for MIR199A1 Gene

Back to Top

Content