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Aliases for MIR199A1 Gene

Subcategory (RNA class) for MIR199A1 Gene


Quality Score for this RNA gene is


Aliases for MIR199A1 Gene

  • MicroRNA 199a-1 2 3 5
  • Hsa-Mir-199a-1 3
  • MiR-199a-3p 3
  • Mir-199a-1 3
  • MIR-199-S 3
  • MIRN199A1 3

External Ids for MIR199A1 Gene

Previous HGNC Symbols for MIR199A1 Gene

  • MIRN199A1

Previous GeneCards Identifiers for MIR199A1 Gene

  • GC19M010928

Summaries for MIR199A1 Gene

Entrez Gene Summary for MIR199A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR199A1 Gene

MIR199A1 (MicroRNA 199a-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cardiomyocyte hypertrophy and SRF and miRs in Smooth Muscle Differentiation and Proliferation.

fRNAdb sequence ontologies for MIR199A1 Gene - the ORGUL cluster for this gene includes several descriptions:

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR199A1

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR199A1 Gene

Genomics for MIR199A1 Gene

Regulatory Elements for MIR199A1 Gene

Enhancers for MIR199A1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR199A1 on UCSC Golden Path with GeneCards custom track

Promoters for MIR199A1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR199A1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR199A1 Gene

10,817,426 bp from pter
10,817,496 bp from pter
71 bases
Minus strand

Genomic View for MIR199A1 Gene

Genes around MIR199A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR199A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR199A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR199A1 Gene

ORGUL Member Location for MIR199A1 Gene

ORGUL Member Location for MIR199A1 gene

Proteins for MIR199A1 Gene

Post-translational modifications for MIR199A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR199A1 Gene

Domains & Families for MIR199A1 Gene

Gene Families for MIR199A1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR199A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR199A1 Gene

Function for MIR199A1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR199A1 Gene

Localization for MIR199A1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR199A1 Gene

Pathways & Interactions for MIR199A1 Gene

genes like me logo Genes that share pathways with MIR199A1: view

Pathways by source for MIR199A1 Gene

Interacting Proteins for MIR199A1 Gene

Gene Ontology (GO) - Biological Process for MIR199A1 Gene


No data available for SIGNOR curated interactions for MIR199A1 Gene

Drugs & Compounds for MIR199A1 Gene

No Compound Related Data Available

Transcripts for MIR199A1 Gene

fRNAdb Secondary structures for MIR199A1 Gene

  • FR299132
  • hsa-mir-199a-1_MI0000242_Homo_sapiens_miR-199a-1_stem-loop_hairpin
  • hsa-miR-199b-3p_MIMAT0004563_Homo_sapiens_miR-199b-3p_mature

mRNA/cDNA for MIR199A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR199A1 Gene

No ASD Table

Relevant External Links for MIR199A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR199A1 Gene

mRNA expression in normal human tissues for MIR199A1 Gene

genes like me logo Genes that share expression patterns with MIR199A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR199A1 Gene

Orthologs for MIR199A1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR199A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-3604-1 36
  • 86 (a)
(Canis familiaris)
Mammalia cfa-mir-199-1 36
  • 86 (a)
(Monodelphis domestica)
Mammalia mdo-mir-199b-3 36
  • 56 (a)
(Mus musculus)
Mammalia Mir199a-1 36
  • 91 (a)
(Pan troglodytes)
Mammalia ptr-mir-199a-1 36
  • 100 (a)
(Anolis carolinensis)
Reptilia aca-mir-199a-1 36
  • 57 (a)
(Danio rerio)
Actinopterygii dre-mir-199-2 36
  • 63 (a)
Species with no ortholog for MIR199A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR199A1 Gene

Gene Tree for MIR199A1 (if available)
Gene Tree for MIR199A1 (if available)

Paralogs for MIR199A1 Gene

No data available for Paralogs for MIR199A1 Gene

Variants for MIR199A1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR199A1 Gene

Variant ID Type Subtype PubMed ID
nsv833746 CNV Loss 17160897
nsv833748 CNV Loss 17160897
nsv911049 CNV Loss 21882294
nsv2416 CNV Insertion 18451855

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR199A1 Gene

Disorders for MIR199A1 Gene

Relevant External Links for MIR199A1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR199A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR199A1 Gene

Publications for MIR199A1 Gene

  1. Discovery and validation of extracellular/circulating microRNAs during idiopathic pulmonary fibrosis disease progression. (PMID: 25725128) Yang G. … Xu Z. (Gene 2015) 3 67
  2. Identification of human fetal liver miRNAs by a novel method. (PMID: 15978578) Fu H. … Zheng X. (FEBS Lett. 2005) 1 3
  3. New microRNAs from mouse and human. (PMID: 12554859) Lagos-Quintana M. … Tuschl T. (RNA 2003) 1 3
  4. Vertebrate microRNA genes. (PMID: 12624257) Lim L.P. … Bartel D.P. (Science 2003) 1 3
  5. CCL5 promotes vascular endothelial growth factor expression and induces angiogenesis by down-regulating miR-199a in human chondrosarcoma cells. (PMID: 25444917) Liu G.T. … Tang C.H. (Cancer Lett. 2015) 3

Products for MIR199A1 Gene

Sources for MIR199A1 Gene